Protective autoimmunity is a condition in which cells of the adaptive immune system contribute to maintenance of the functional integrity of a tissue, or facilitate its repair following an insult. The term ‘protective autoimmunity’ was coined by Prof. Michal Schwartz of the Weizmann Institute of Science (Israel), whose pioneering studies were the first to demonstrate that autoimmune T lymphocytes can have a beneficial role in repair, following an injury to the central nervous system (CNS). Most of the studies on the phenomenon of protective autoimmunity were conducted in experimental settings of various CNS pathologies and thus reside within the scientific discipline of neuroimmunology.
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Protectiveautoimmunity is a condition in which cells of the adaptive immune system contribute to maintenance of the functional integrity of a tissue...
Autoimmune disease Protectiveautoimmunity Psychoneuroimmunology The Editors of Encyclopaedia Britannica (20 November 2018). "Autoimmunity". Health & Medicine...
of injury or disease.[citation needed] Schwartz coined the term protectiveautoimmunity [citation needed]and discovered roles for immune cells in repair...
brain injury, a pioneering finding that began the study of the protective roles of autoimmunity in CNS disease. This was the beginning of Kipnis' career exploring...
sufficient evidence to indicate that these diseases are caused by autoimmunity. Autoimmunity Autoantibody For detailed information on Goodpasture syndrome...
suppress unwanted responses resulting from autoimmunity, allergy, and transplant rejection, and to stimulate protective responses against pathogens that largely...
for their role in allergy and anaphylaxis, mast cells play an important protective role as well, being intimately involved in wound healing, angiogenesis...
consensus criteria for the diagnosis of Raynaud's phenomenon". Journal of Autoimmunity. 48–49: 60–5. doi:10.1016/j.jaut.2014.01.020. PMC 4018202. PMID 24491823...
pathway database Reactome: Interleukin-12 family IL-12 is linked with autoimmunity. Administration of IL-12 to people suffering from autoimmune diseases...
from harmful overactivity of the immune system against self (so-called autoimmunity). These include rheumatoid arthritis, systemic lupus erythematosus, multiple...
healing, and also in pathologic processes, including inflammations, autoimmunity, tumors, and digestive organs damages. Th22 cells are mainly defined...
stools precedes islet autoimmunity by several months: possible evidence for slowly operating mechanisms in virus-induced autoimmunity". Diabetologia. 60...
cell compartments at similar frequencies, implications for autoimmunity". Journal of Autoimmunity. 77: 76–88. doi:10.1016/j.jaut.2016.11.001. PMC 6066671...
Jancic CC (16 October 2018). "γδ T Lymphocytes: An Effector Cell in Autoimmunity and Infection". Frontiers in Immunology. 9: 2389. doi:10.3389/fimmu.2018...
"Glycans in the immune system and The Altered Glycan Theory of Autoimmunity". J Autoimmun. 57 (6): 1–13. doi:10.1016/j.jaut.2014.12.002. PMC 4340844. PMID 25578468...
inflammatory demyelinating polyneuropathy. Some variants of CIDP present autoimmunity against proteins of the node of Ranvier. These variants comprise a subgroup...
may make T-cells susceptible to react to the orexin-releasing neurons (autoimmunity) after being stimulated by infection with H1N1 influenza. In addition...
serotyping. Current serotyping can resolve, in one step, DQ8. HLA typing in autoimmunity is being increasingly used as a tool in diagnosis. In celiac disease...
immune system and The Altered Glycan Theory of Autoimmunity: a critical review". Journal of Autoimmunity. 57 (6): 1–13. doi:10.1016/j.jaut.2014.12.002...
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