Global Information Lookup Global Information

Prilocaine information


Prilocaine
Clinical data
Trade namesCitanest
AHFS/Drugs.comMonograph
MedlinePlusa603026
License data
  • EU EMA: by INN
  • US DailyMed: Prilocaine
Pregnancy
category
  • AU: A
Routes of
administration
Subcutaneous
ATC code
  • N01BB04 (WHO)
Legal status
Legal status
  • AU: S4 (Prescription only)
  • US: ℞-only
Pharmacokinetic data
Protein binding55%
MetabolismLiver and kidney
Elimination half-life10-150 minutes, longer with impaired liver or kidney function
Identifiers
IUPAC name
  • (RS)-N-(2-methylphenyl)-N2-propylalaninamide
CAS Number
  • 721-50-6 checkY
PubChem CID
  • 4906
IUPHAR/BPS
  • 7276
DrugBank
  • DB00750 checkY
ChemSpider
  • 4737 checkY
UNII
  • 046O35D44R
KEGG
  • D00553 checkY
  • as HCl: D01243 checkY
ChEBI
  • CHEBI:8404 checkY
ChEMBL
  • ChEMBL1194 checkY
CompTox Dashboard (EPA)
  • DTXSID7031955 Edit this at Wikidata
ECHA InfoCard100.010.871 Edit this at Wikidata
Chemical and physical data
FormulaC13H20N2O
Molar mass220.316 g·mol−1
3D model (JSmol)
  • Interactive image
ChiralityRacemic mixture
Melting point37 to 38 °C (99 to 100 °F)
SMILES
  • O=C(Nc1ccccc1C)C(NCCC)C
InChI
  • InChI=1S/C13H20N2O/c1-4-9-14-11(3)13(16)15-12-8-6-5-7-10(12)2/h5-8,11,14H,4,9H2,1-3H3,(H,15,16) checkY
  • Key:MVFGUOIZUNYYSO-UHFFFAOYSA-N checkY
  (verify)

Prilocaine (/ˈprləˌkn/[1]) is a local anesthetic of the amino amide type first prepared by Claes Tegner and Nils Löfgren. In its injectable form (trade name Citanest), it is often used in dentistry. It is also often combined with lidocaine as a topical preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia. As it has low cardiac toxicity, it is commonly used for intravenous regional anaesthesia (IVRA).

  1. ^ "Prilocaine". Merriam-Webster.com Dictionary. Retrieved 2016-01-21.

and 27 Related for: Prilocaine information

Request time (Page generated in 0.5755 seconds.)

Prilocaine

Last Update:

Prilocaine (/ˈpraɪləˌkeɪn/) is a local anesthetic of the amino amide type first prepared by Claes Tegner and Nils Löfgren. In its injectable form (trade...

Word Count : 459

Dental anesthesia

Last Update:

called septocaine or Ubistesin), bupivacaine (a long-acting anesthetic), prilocaine (also called Citanest), and mepivacaine (also called Carbocaine or Polocaine)...

Word Count : 5497

Frenulectomy of the penis

Last Update:

office. First the physician applies a local anesthetic, such as lidocaine/prilocaine cream on the frenulum and surrounding area. If the patient retains any...

Word Count : 185

Local anesthetic

Last Update:

Chloroprocaine Medium Duration of Action and Medium Potency Lidocaine Prilocaine High Duration and High Potency Tetracaine Bupivacaine Cinchocaine Ropivacaine...

Word Count : 7118

Methemoglobinemia

Last Update:

sulfonamides, and dapsone), local anesthetics (especially articaine, benzocaine, prilocaine, and lidocaine), and aniline dyes, metoclopramide, rasburicase, umbellulone...

Word Count : 2555

Tumescent anesthesia

Last Update:

liposuction. Prilocaine is also widely used, although it is not formally approved for tumescent anesthesia in the USA. A combination of lidocaine/prilocaine has...

Word Count : 671

Lidocaine

Last Update:

to suggest that the use of alternative anesthetic medications such as prilocaine, procaine, bupivacaine, ropivacaine, or levobupivacaine may decrease the...

Word Count : 4424

ATC code N01

Last Update:

combinations N01BB01 Bupivacaine N01BB02 Lidocaine N01BB03 Mepivacaine N01BB04 Prilocaine N01BB05 Butanilicaine N01BB06 Cinchocaine N01BB07 Etidocaine N01BB08 Articaine...

Word Count : 336

Ketamine

Last Update:

Lidocaine Mepivacaine Meprylcaine Metabutoxycaine Orthocaine Piperocaine Prilocaine Procaine Propoxycaine Proxymetacaine Risocaine Tetracaine Trimecaine Analgesics:...

Word Count : 11403

Methemoglobin

Last Update:

Various pharmaceutical compounds Local anesthetic agents, especially prilocaine and benzocaine. Amyl nitrite, chloroquine, dapsone, nitrates, nitrites...

Word Count : 1004

Paresthesia

Last Update:

care can include the use of topical numbing creams, such as lidocaine or prilocaine. Ketamine has also been successfully used, but is generally not approved...

Word Count : 2510

Fear of needles

Last Update:

topical anesthetic cream that is a eutectic mixture of lidocaine and prilocaine. It is a prescription cream in the United States, and is available without...

Word Count : 2902

Cocaine

Last Update:

Lidocaine Mepivacaine Meprylcaine Metabutoxycaine Orthocaine Piperocaine Prilocaine Procaine Propoxycaine Proxymetacaine Risocaine Tetracaine Trimecaine Analgesics:...

Word Count : 17679

Procaine

Last Update:

(Xylocaine) exist. Like other local anesthetics (such as mepivacaine, and prilocaine), procaine is a vasodilator, thus is often coadministered with epinephrine...

Word Count : 1132

Anesthetic

Last Update:

Cinchocaine(INN/BAN)/Dibucaine(USAN) Etidocaine Levobupivacaine Lidocaine Mepivacaine Prilocaine Ropivacaine Local anesthetic agents prevent the transmission of nerve...

Word Count : 2220

Toluidine

Last Update:

cyanoacrylate glues. In some patients o-toluidine is a metabolite of prilocaine, which may cause methemoglobinemia. This is then treated with methylene...

Word Count : 363

Analgesic

Last Update:

contain anesthetic drugs such as lidocaine, tetracaine, benzocaine, and prilocaine in a cream, ointment, or gel. Topical nonsteroidal anti-inflammatory drugs...

Word Count : 5952

Crack cocaine

Last Update:

lidocaine, procaine, hexylcaine, bupivacaine, benoxinate, mepivacaine, prilocaine, etidocaine, benzocaine, chloroprocaine, propoxycaine, dyclonine, dibucaine...

Word Count : 3913

Topiramate

Last Update:

Lidocaine Mepivacaine Meprylcaine Metabutoxycaine Orthocaine Piperocaine Prilocaine Procaine Propoxycaine Proxymetacaine Risocaine Tetracaine Trimecaine Analgesics:...

Word Count : 3780

Amino esters

Last Update:

Lidocaine# Mepivacaine Prilocaine Trimecaine Combinations Anesthetic/vasoconstrictor Bupivacaine/meloxicam Lidocaine/prilocaine TAC Iontocaine #WHO-EM...

Word Count : 147

Articaine

Last Update:

that it is significantly more likely to do so if either articaine or prilocaine is used.” In another paper by the same authors, 19 reported paresthesia...

Word Count : 1862

Spinal anaesthesia

Last Update:

lidocaine (lignocaine), tetracaine, procaine, ropivacaine, levobupivicaine, prilocaine, or cinchocaine may also be used. Commonly opioids are added to improve...

Word Count : 2511

Gabapentin

Last Update:

Lidocaine Mepivacaine Meprylcaine Metabutoxycaine Orthocaine Piperocaine Prilocaine Procaine Propoxycaine Proxymetacaine Risocaine Tetracaine Trimecaine Analgesics:...

Word Count : 8581

Felypressin

Last Update:

posterior pituitary hormone. It is added to some local anaesthetics such as prilocaine in a concentration of 0.03 IU/ml. Felypressin is a Vasopressin 1 agonist...

Word Count : 130

Benzocaine

Last Update:

Lidocaine Mepivacaine Meprylcaine Metabutoxycaine Orthocaine Piperocaine Prilocaine Procaine Propoxycaine Proxymetacaine Risocaine Tetracaine Trimecaine Analgesics:...

Word Count : 2027

Calcium channel blocker

Last Update:

Lidocaine Mepivacaine Meprylcaine Metabutoxycaine Orthocaine Piperocaine Prilocaine Procaine Propoxycaine Proxymetacaine Risocaine Tetracaine Trimecaine Analgesics:...

Word Count : 3266

Promethazine

Last Update:

Lidocaine Mepivacaine Meprylcaine Metabutoxycaine Orthocaine Piperocaine Prilocaine Procaine Propoxycaine Proxymetacaine Risocaine Tetracaine Trimecaine Analgesics:...

Word Count : 2681

PDF Search Engine © AllGlobal.net