For the novel by Günter Grass, see Local Anaesthetic (novel).
Many local anesthetics fall into two general chemical classes, amino esters (top) and amino amides (bottom).
A local anesthetic (LA) is a medication that causes absence of all sensation (including pain) in a specific body part without loss of consciousness,[1] providing local anesthesia, as opposed to a general anesthetic, which eliminates all sensation in the entire body and causes unconsciousness.[1] Local anesthetics are most commonly used to eliminate pain during or after surgery.[2] When it is used on specific nerve pathways (local anesthetic nerve block), paralysis (loss of muscle function) also can be induced.[3]
^ ab"Types of Anaesthesia". nhs.uk. 17 October 2017. Retrieved 10 April 2023.
^"Local anaesthesia". nhs.uk. 19 October 2017. Retrieved 10 April 2023.
^Greenbaum, R. A.; Kaye, G.; Mason, P. D. (July 1987). "Experience with nalbuphine, a new opioid analgesic, in acute myocardial infarction". Journal of the Royal Society of Medicine. 80 (7): 418–421. doi:10.1177/014107688708000708. ISSN 0141-0768. PMC 1290901. PMID 3309298.
A localanesthetic (LA) is a medication that causes absence of all sensation (including pain) in a specific body part without loss of consciousness, providing...
into two broad classes: general anesthetics, which result in a reversible loss of consciousness, and localanesthetics, which cause a reversible loss of...
conditions, like localanesthetic toxicity, airway trauma or malignant hyperthermia, can be more directly attributed to specific anesthetic drugs and techniques...
A topical anesthetic is a localanesthetic that is used to numb the surface of a body part. They can be used to numb any area of the skin as well as the...
This is a list of localanesthetic agents. Not all of these drugs are still used in clinical practice and in research. Some are primarily of historical...
achieved. Clinical localanesthetics belong to one of two classes: aminoamide and aminoester localanesthetics. Synthetic localanesthetics are structurally...
signals traveling along a nerve, often for the purpose of pain relief. Localanesthetic nerve block (sometimes referred to as simply "nerve block") is a short-term...
involving the lower extremities and surgeries below the umbilicus. The localanesthetic with or without an opioid injected into the cerebrospinal fluid provides...
anesthesia to dentistry. It includes localanesthetics, sedation, and general anesthesia. In dentistry, localanesthetic medications (LA) are often used to...
anesthesia, in which localanesthetics are used to block pain from a large area (or nerve distribution). Cocaine, the first localanesthetic was used topically...
unclear if use in pregnancy or breastfeeding is safe. Benzonatate is a localanesthetic and voltage-gated sodium channel blocker.[unreliable medical source...
least medical imaging (generally X-ray initially) and/or response to localanesthetic injection is necessary for workup. However, imaging studies are unable...
Articaine is a dental amide-type localanesthetic. It is the most widely used localanesthetic in a number of European countries and is available in many...
Contact dermatitis is a type of acute or chronic inflammation of the skin caused by exposure to chemical or physical agents. Symptoms of contact dermatitis...
among others, is a localanesthetic of the amino amide type. It is also used to treat ventricular tachycardia. When used for local anaesthesia or in nerve...
the veterinary medicine field dedicated to the proper administration of anesthetic agents to non-human animals to control their consciousness during procedures...
an ester localanesthetic, was approved for medical use in the United States in December 2017, and is indicated for the introduction of local anesthesia...
Procaine is a localanesthetic drug of the amino ester group. It is most commonly used in dental procedures to numb the area around a tooth and is also...
appropriate short-acting local anesthetic and drugs such as levobupivacaine or ropivacaine are appropriate long-acting localanesthetics. The amount of drugs needed...
epidural route is used by physicians and nurse anesthetists to administer localanesthetic agents, analgesics, diagnostic medicines such as radiocontrast agents...
blocking injection utilizing a combination of corticosteroids and localanesthetic. The condition predominantly affects women over the age of 40, though...
Amino esters are a class of localanesthetics. They are named for their ester bond and are unlike amide local anaesthetics. Structurally, amino esters...
to the right or left (medio-lateral episiotomy), is performed under localanesthetic (pudendal anesthesia), and is sutured after delivery. Its routine use...
voltage-gated sodium channels via the localanesthetic binding site, and this underlies its potent localanesthetic properties. Similarly to various other...
(IVRA) or Bier's block anesthesia is an anesthetic technique on the body's extremities where a localanesthetic is injected intravenously and isolated...
techniques. If these medications cannot effectively manage the pain, localanesthetic may be directly injected to the nerve in a procedure called a nerve...
cystoscope. Flexible cystoscopy is carried out with local anaesthesia on both sexes. Typically, a topical anesthetic, most often xylocaine gel (common brand names...
Benzocaine, sold under the brand name Orajel amongst others, is a localanesthetic, belonging to the amino ester drug class, commonly used as a topical...
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