Risk of fetal injury due to the use of a pharmaceutical
The pregnancy category of a medication is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother during pregnancy. It does not include any risks conferred by pharmaceutical agents or their metabolites in breast milk.
Every drug has specific information listed in its product literature. The British National Formulary used to provide a table of drugs to be avoided or used with caution in pregnancy, and did so using a limited number of key phrases, but now Appendix 4 (which was the Pregnancy table) has been removed. Appendix 4 is now titled "Intravenous Additives".[1] However, information that was previously available in the former Appendix 4 (pregnancy) and Appendix 5 (breastfeeding) is now available in the individual drug monographs.[2]
^"Appendix 4: Pregnancy". British National Formulary (55 ed.). March 2008.[incomplete short citation]
^British National Formulary, online January 2016
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The pregnancycategory of a medication is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother...
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(related to sickle cell anemia). Topical clotrimazole is categorized as pregnancycategory B. Small amounts of clotrimazole may be absorbed systemically following...
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implants in the uterus. It falls under the category of gestational trophoblastic diseases. During a molar pregnancy, the uterus contains a growing mass characterized...
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bone loss, cataracts, easy bruising, or muscle weakness. It is in pregnancycategory C in the United States, meaning that it should only be used when the...
reported and those with prior liver problems are at greater risk. It is pregnancycategory D in Australia, meaning it may cause harm if taken by pregnant women...
in people with liver disease or kidney disease. It is grouped in pregnancycategory C (risk not ruled out: Animal reproduction studies have shown an adverse...
not clinically appropriate or is contraindicated. Cinacalcet has pregnancycategory C in the US, meaning that adequate and well-controlled studies involving...
and continued for the first two days at altitude. Acetazolamide is pregnancycategory B3 in Australia, which means that studies in rats, mice and rabbits...
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million people, and the prevalence 233 per million people. Scleroderma in pregnancy is a complex situation; it increases the risk to both mother and child...
Clostridium difficile, a cause of diarrhea, are also possible. Use during pregnancy or breast feeding does not appear to be harmful to the fetus. It can be...
are premature or have impaired bilirubin binding. Ceftriaxone is pregnancycategory B [clarification needed]. It has not been observed to cause birth...
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