Porcine reproductive and respiratory syndrome virus 2 information
Species of virus
Betaarterivirus suid 2
Virus classification
(unranked):
Virus
Realm:
Riboviria
Kingdom:
Orthornavirae
Phylum:
Pisuviricota
Class:
Pisoniviricetes
Order:
Nidovirales
Family:
Arteriviridae
Genus:
Betaarterivirus
Subgenus:
Ampobartevirus
Species:
Betaarterivirus suid 2
Synonyms
Porcine reproductive and respiratory syndrome virus 2
Betaarterivirus suid 2 is a species of enveloped, positive-strand RNA viruses which infect domestic pigs.[1][2] Members of the species are also known as porcine reproductive and respiratory syndrome virus 2. Member viruses are a type of the porcine reproductive and respiratory syndrome viruses (PRRSV). The two types of PRRSV are distinguished by which genomic cluster they are associated with. Type 1 is associated with a LV cluster. Type 2 is associated with a VR2332 cluster.[3]
PRRSV is in the Arteriviridae family and the order Nidovirales.[4] It has a positive sense RNA genome that is 15 kb long. This genome consists of ten open reading frames (ORFs) with a 5' untranslated region (UTR) and a 3' UTR.[3] PRRSV causes porcine reproductive and respiratory syndrome in swine. This syndrome results in failure during breeding and respiratory problems. Type 2 PRRSV was first seen in the United States in 1987. However, it has now spread worldwide to commercial swine facilities.[5]
Within the swine industry, porcine reproductive and respiratory syndrome causes interstitial pneumonia of grown swine and fetal death. Early gestation infection of a maternal swine can lead to embryonic infection. During mid-gestation, the fetuses are protected as the virus can not pass the placenta. However, in late state gestation transplacental infection to and from fetuses can occur and large scale reproductive failure may occur.[6]
^ abBrar, Manreetpal Singh; Shi, Mang; Murtaugh, Michael P.; Leung, Frederick Chi-Ching (2015). "Evolutionary diversification of type 2 porcine reproductive and respiratory syndrome virus". Journal of General Virology. 96 (7): 1570–1580. doi:10.1099/vir.0.000104. PMID 25711962. S2CID 21578823.
^Yun, Sang-Im; Lee, Young-Min (2013-12-01). "Overview: Replication of porcine reproductive and respiratory syndrome virus". Journal of Microbiology. 51 (6): 711–723. doi:10.1007/s12275-013-3431-z. ISSN 1225-8873. PMC 7091224. PMID 24385346.
^Shi, Mang; Lam, Tommy Tsan-Yuk; Hon, Chung-Chau; Murtaugh, Michael P.; Davies, Peter R.; Hui, Raymond Kin-Hei; Li, Jun; Wong, Lina Tik-Wim; Yip, Chi-Wai (2010-09-01). "Phylogeny-Based Evolutionary, Demographical, and Geographical Dissection of North American Type 2 Porcine Reproductive and Respiratory Syndrome Viruses". Journal of Virology. 84 (17): 8700–8711. doi:10.1128/jvi.02551-09. ISSN 0022-538X. PMC 2919017. PMID 20554771.
^Ladinig, Andrea; Ashley, Carolyn; Detmer, Susan E.; Wilkinson, Jamie M.; Lunney, Joan K.; Plastow, Graham; Harding, John CS (2015-09-25). "Maternal and fetal predictors of fetal viral load and death in third trimester, type 2 porcine reproductive and respiratory syndrome virus infected pregnant gilts". Veterinary Research. 46 (1): 107. doi:10.1186/s13567-015-0251-7. ISSN 1297-9716. PMC 4582889. PMID 26407558.
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successfully observed antiviral activity against the porcinereproductiveandrespiratorysyndromevirus (PRRSV) using DRACOs in vitro. As of December 2015[update]...
Renukaradhya, Gourapura J. (2016-02-15). "PorcineReproductiveandRespiratorySyndromeVirus (PRRSV): Pathogenesis and Interaction with the Immune System"...
obesity, type 2 diabetes, and cardiovascular disease (CVD) to develop. Polycystic ovary syndrome – a complex syndrome in women in the reproductive years where...
Osorio FA (1997). "Porcinereproductiveandrespiratorysyndromevirus replicates in testicular germ cells, alters spermatogenesis, and induces germ cell...
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resistant to porcine reproductiveandrespiratorysyndrome, one of the world's most costly animal diseases. 21 June – The US National Science and Technology Council...
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