Plasma osmolality measures the body's electrolyte–water balance.[1] There are several methods for arriving at this quantity through measurement or calculation.
Osmolality and osmolarity are measures that are technically different, but functionally the same for normal use. Whereas osmolality (with an "l") is defined as the number of osmoles (Osm) of solute per kilogram of solvent (osmol/kg or Osm/kg), osmolarity (with an "r") is defined as the number of osmoles of solute per liter (L) of solution (osmol/L or Osm/L). As such, larger numbers indicate a greater concentration of solutes in the plasma.
calculation. Osmolality and osmolarity are measures that are technically different, but functionally the same for normal use. Whereas osmolality (with an...
volume. Plasma osmolarity, the osmolarity of blood plasma, can be calculated from plasmaosmolality by the following equation: Osmolarity = osmolality × (ρsol...
Plasmaosmolality with typical fluid intake often averages approximately 290 mOsm/kg H2O in humans. Some mammals are capable of higher osmolality than...
hyponatremia is associated with a low plasmaosmolality. The term "hypotonic hyponatremia" is also sometimes used. When the plasma osmolarity is low, the extracellular...
rise in plasmaosmolality is detected by the hypothalamus, which communicates directly with the posterior pituitary gland. An increase in osmolality causes...
serum osmolality and calculated serum osmolality. The osmol gap is typically calculated as: OG = measured serum osmolality − calculated osmolality Calculated...
rise in plasmaosmolality is detected by the hypothalamus, which communicates directly with the posterior pituitary gland. An increase in osmolality causes...
to the venous circulation leading to hypotonic hyponatremia (a low plasmaosmolality and low sodium levels). The causes of SIADH are commonly grouped into...
measured plasmaosmolality of 284 mOsm and urine osmolality of 62 mOsm. Adults have higher rates with a plasmaosmolality of 330 mOsm and urine osmolality of...
scientists found to commonly suffer from dehydration. Scientists have used plasmaosmolality to find more information about the form of dehydration grey parrots...
control of fluid balance. Its levels in the blood vary with the osmolality of the plasma, which is measured in the hypothalamus of the brain. Aldosterone's...
infarcts, or contusions due to a local plasmaosmolality pressure gradient when compared to the high osmolality in the affected tissue. Interstitial edema...
resulting in small volumes of highly concentrated urine and decreased plasmaosmolality. Antidiuretic hormone is released in response to high solute concentrations...
before fluid loss Osmb = Body osmolarity before loss (almost equal to plasmaosmolality of 275-299 milli-osmoles per kilogram) TBWb = Total body water before...
{U_{osm}}{P_{osm}}})V} For example, for an individual with a urine osmolality of 140 mOsm/L, plasmaosmolality of 280 mOsm/L, and a urine production of 4 ml/min, the...
hyponatremia relies on three factors: volume status, plasmaosmolality, urine sodium levels and urine osmolality. Many individuals with mild hyponatremia will...
water and electrolyte regulation and balance. V2 receptors maintain plasmaosmolality and are coupled to aquaporin channels in the collecting ducts of kidneys...
elevated urinary PGE2 and inappropriately low plasma ADH levels in the setting of low plasmaosmolality. Thiazide-associated hyponatremia is often more...
reliable indicator of thyroid status in the presence of abnormalities in plasma protein binding. This test is rarely used now that reliable free thyroxine...
in consciousness levels is primarily attributed to an increase in plasmaosmolality. lethargy may ultimately progress to a coma which is more common in...
Osmoreceptors are also found in the kidneys where they also modulate osmolality. Osmoreceptors are located in two of the circumventricular organs — the...
mRNA on the choroid plexus were discovered as a result of increased plasmaosmolality. The increase after a reduction of brain water content from salt water...
It plays a central role in the homeostatic regulation of blood pressure, plasma sodium (Na+), and potassium (K+) levels. It does so primarily by acting...
fluid and plasma volume, therefore increasing blood flow to the kidney, particularly the peritubular capillaries. This reduces medullary osmolality and thus...
stimulates secretion, even in the face of decreased osmolality of the plasma: it supersedes osmolality, but with a milder effect. In other words, vasopressin...
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