Global Information Lookup Global Information

Phenylacetic acid information


Phenylacetic acid
Structural formula
Ball-and-stick model of phenylacetic acid
Names
Preferred IUPAC name
Phenylacetic acid
Systematic IUPAC name
2-Phenylethanoic acid
Other names
α-Toluic acid
Benzeneacetic acid
2-Phenylacetic acid
β-Phenylacetic acid
Identifiers
CAS Number
  • 103-82-2 checkY
3D model (JSmol)
  • Interactive image
3DMet
  • B02157
Beilstein Reference
1099647
ChEBI
  • CHEBI:30745 checkY
ChEMBL
  • ChEMBL1044 checkY
ChemSpider
  • 10181341 checkY
DrugBank
  • DB09269
ECHA InfoCard 100.002.862 Edit this at Wikidata
EC Number
  • 203-148-6
Gmelin Reference
68976
KEGG
  • C07086
PubChem CID
  • 999
RTECS number
  • AJ2430000
UNII
  • ER5I1W795A checkY
CompTox Dashboard (EPA)
  • DTXSID2021656 Edit this at Wikidata
InChI
  • InChI=1S/C8H8O2/c9-8(10)6-7-4-2-1-3-5-7/h1-5H,6H2,(H,9,10) checkY
    Key: WLJVXDMOQOGPHL-UHFFFAOYSA-N checkY
  • InChI=1/C8H8O2/c9-8(10)6-7-4-2-1-3-5-7/h1-5H,6H2,(H,9,10)
    Key: WLJVXDMOQOGPHL-UHFFFAOYAR
SMILES
  • O=C(O)Cc1ccccc1
Properties
Chemical formula
C8H8O2
Molar mass 136.15 g/mol
Appearance white solid
Odor honey-like
Density 1.0809 g/cm3
Melting point 76 to 77 °C (169 to 171 °F; 349 to 350 K)
Boiling point 265.5 °C (509.9 °F; 538.6 K)
Solubility in water
15 g/L
Acidity (pKa) 4.31 (H2O)[1]
Magnetic susceptibility (χ)
-82.72·10−6 cm3/mol
Hazards
GHS labelling:
Pictograms
GHS05: CorrosiveGHS07: Exclamation mark
Signal word
Danger
Hazard statements
H318, H319
Precautionary statements
P264, P280, P305+P351+P338, P310, P337+P313
NFPA 704 (fire diamond)
NFPA 704 four-colored diamondHealth 2: Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury. E.g. chloroformFlammability 1: Must be pre-heated before ignition can occur. Flash point over 93 °C (200 °F). E.g. canola oilInstability 0: Normally stable, even under fire exposure conditions, and is not reactive with water. E.g. liquid nitrogenSpecial hazards (white): no code
2
1
0
Safety data sheet (SDS) External MSDS
Legal status
  • BR: Class D1 (Drug precursors)[2]
Related compounds
Related compounds
Benzoic acid, Phenylpropanoic acid, Cinnamic acid
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
checkY verify (what is checkY☒N ?)
Infobox references

Phenylacetic acid (conjugate base phenylacetate), also known by various synonyms, is an organic compound containing a phenyl functional group and a carboxylic acid functional group. It is a white solid with a strong honey-like odor. Endogenously, it is a catabolite of phenylalanine. As a commercial chemical, because it can be used in the illicit production of phenylacetone (used in the manufacture of substituted amphetamines), it is subject to controls in countries including the United States and China.[3]

  1. ^ Haynes, William M., ed. (2016). CRC Handbook of Chemistry and Physics (97th ed.). CRC Press. pp. 5–89. ISBN 978-1498754286.
  2. ^ Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-15.
  3. ^ "List of Regulated Drug Precursor Chemicals in China". Archived from the original on 17 August 2015. Retrieved 27 April 2015.

and 26 Related for: Phenylacetic acid information

Request time (Page generated in 0.834 seconds.)

Phenylacetic acid

Last Update:

Phenylacetic acid (conjugate base phenylacetate), also known by various synonyms, is an organic compound containing a phenyl functional group and a carboxylic...

Word Count : 623

Diclofenac

Last Update:

"diclofenac" derives from its chemical name: 2-(2,6-dichloranilino) phenylacetic acid. It was patented in Germany in 1978 by Ciba-Geigy (now Novartis)....

Word Count : 5599

Phenethylamine

Last Update:

(MAO-B) and then aldehyde dehydrogenase (ALDH), which converts it to phenylacetic acid. This means that for significant concentrations to reach the brain...

Word Count : 4243

Mandelic acid

Last Update:

trans-cinnamate via phenylacetic acid, which is hydroxylated. Phenylpyruvic acid is another precursor to mandelic acid. Derivatives of mandelic acid are formed...

Word Count : 935

Precursor chemicals

Last Update:

manufacture of narcotic drugs and psychoactive substances. For example, phenylacetic acid is used legally in the production of penicillin, flavourings, perfume...

Word Count : 928

Brazilian Controlled Drugs and Substances Act

Last Update:

(N-Phenyl-4-piperidinamine) 23056-29-3 Anthranilic acid Phenylacetic acid Lysergic acid N-Acetylanthranilic acid Alpha-phenylacetoacetonitrile (APAAN) (CAS:...

Word Count : 1685

Retrosynthetic analysis

Last Update:

from a single product. Shown below is a retrosynthetic analysis of phenylacetic acid: In planning the synthesis, two synthons are identified. A nucleophilic...

Word Count : 749

Auxin

Last Update:

include indole-3-acetic acid, 4-chloroindole-3-acetic acid, phenylacetic acid, indole-3-butyric acid, and indole-3-propionic acid. However, most of the...

Word Count : 5180

Willgerodt rearrangement

Last Update:

pyridine) is the conversion of acetophenone to 2-phenylacetamide and phenylacetic acid The related Willgerodt–Kindler reaction takes place with elemental...

Word Count : 449

Sinaloa Cartel

Last Update:

(phenyl-2-propanone) is usually obtained from phenylacetic acid and acetic anhydride, with phenylacetic acid possibly arising from benzaldehyde, benzylcyanide...

Word Count : 17218

Benzyl cyanide

Last Update:

nitriles. It can be hydrolyzed to give phenylacetic acid or it can be used in the Pinner reaction to yield phenylacetic acid esters. Hydrogenation gives β-phenethylamine...

Word Count : 850

Cinnamic acid

Last Update:

Cinnamic acid is an organic compound with the formula C6H5-CH=CH-COOH. It is a white crystalline compound that is slightly soluble in water, and freely...

Word Count : 687

Phenethyl alcohol

Last Update:

is also possible to produce phenethyl alcohol by the reduction of phenylacetic acid using sodium borohydride and iodine in THF. Phenethyl alcohol is found...

Word Count : 475

Etonitazene

Last Update:

and 7-nitrobenzimidazoles. Varying the choice of the substituted phenylacetic acid imino ether affords compounds with a diversity of substituents on...

Word Count : 1952

Methyl phenylacetate

Last Update:

phenylacetate is an organic compound that is the methyl ester of phenylacetic acid, with the structural formula C 6 H 5 CH 2 COOCH 3 {\displaystyle {\ce...

Word Count : 152

Benzoic acid

Last Update:

Benzoic acid /bɛnˈzoʊ.ɪk/ is a white (or colorless) solid organic compound with the formula C6H5COOH, whose structure consists of a benzene ring (C6H6)...

Word Count : 2436

Phenylacetaldehyde

Last Update:

Phenylacetaldehyde is readily oxidized to phenylacetic acid. Therefore will eventually be hydrolyzed and oxidized to yield phenylacetic acid that will be excreted primarily...

Word Count : 765

Maggot therapy

Last Update:

have broad-spectrum antimicrobial activity include allantoin, urea, phenylacetic acid, phenylacetaldehyde, calcium carbonate, proteolytic enzymes, and many...

Word Count : 2546

DEA list of chemicals

Last Update:

methyl ethyl ketone or MEK) Toluene Hydrochloric acid (including anhydrous hydrogen chloride) Sulfuric acid Methyl isobutyl ketone (MIBK) Sodium permanganate...

Word Count : 418

Phenylacetone

Last Update:

the gas-phase ketonic decarboxylation of phenylacetic acid using acetic acid over a ceria-alumina solid acid catalyst. A related laboratory-scale reaction...

Word Count : 1749

Benzilic acid

Last Update:

Benzilic acid is an organic compound with formula C 14H 12O 3 or (C 6H 5)2(HO)C(COOH). It is a white crystalline aromatic acid, soluble in many primary...

Word Count : 225

Synthon

Last Update:

potentially very unstable charged synthons. In planning the synthesis of phenylacetic acid, two synthons are identified: a nucleophilic "COOH−" group, and an...

Word Count : 810

Plastic degradation by marine bacteria

Last Update:

polystyrene molecule is transformed into phenylacetic acid during the upper pathway of styrene metabolism. Phenylacetic acid is first converted into phenylacetyl-coA...

Word Count : 4263

Phenylacetylrinvanil

Last Update:

amide of vanillylamine and ricinoleic acid, with the hydroxyl group on ricinoleic acid esterified with phenylacetic acid. It is used to study the function...

Word Count : 245

Synthetic drug

Last Update:

mitochondria which deaminates free primary and secondary amines) to form phenylacetic acid due to MAO-B selectivity on non-polar aromatic amines. Then, the metabolites...

Word Count : 2877

Rambutan

Last Update:

organic compounds, including beta-damascenone, vanillin, phenylacetic acid, and cinnamic acid. Aromatic rambutan flowers are highly attractive to many...

Word Count : 3146

PDF Search Engine © AllGlobal.net