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Synthetic drug information


Synthetic drugs refer to substances that are artificially modified from naturally-occurring drugs and are capable of exhibiting both therapeutic and psychoactive effects.

In the medical setting, synthetic drugs possess psychotropic effects which can cure insomnia. Since there are limited clinical trials and human studies, the pharmacology and drug effects of most of the synthetic drugs are not well-known. Misuse of synthetic drugs can be fatal so take advice from the professionals before use.

Substances that possess the latter effect are known as New Psychoactive Substances (NPS). Their purpose is to mimic the actions of illicit substances by altering the structure of the original drug. By doing so, the “synthesized drug” can appear in the market without being easily detected. However, the uncertainty in the toxic effects of these substances puts the public's health at risk.[1] At present, these drugs are monitored by the Early Warning System (EWS).The major categories of NPS include synthetic stimulants, synthetic cannabinoids and synthetic depressants. Common examples from these categories are phenethylamines, cannabinoids and benzodiazepines. To exert the psychoactive effect, specific receptors such as cannabinoid, dopamine and serotonin receptors are either stimulated or inhibited[2]

  1. ^ Rinaldi, Raffaella; Bersani, Giuseppe; Marinelli, Enrico; Zaami, Simona (2020-03-07). "The rise of new psychoactive substances and psychiatric implications: A wide‐ranging, multifaceted challenge that needs far‐reaching common legislative strategies". Human Psychopharmacology: Clinical and Experimental. 35 (3): e2727. doi:10.1002/hup.2727. ISSN 0885-6222. PMID 32144953. S2CID 212621941.
  2. ^ Shafi, Abu; Berry, Alex J.; Sumnall, Harry; Wood, David M.; Tracy, Derek K. (2020-09-26). "New psychoactive substances: a review and updates". Therapeutic Advances in Psychopharmacology. 10: 204512532096719. doi:10.1177/2045125320967197. ISSN 2045-1253. PMC 7750892. PMID 33414905.

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