peptidyl-arginine methylation, to asymmetrical-dimethyl arginine
histone arginine methylation
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
10196
71974
Ensembl
ENSG00000185238
ENSMUSG00000030505
UniProt
O60678
Q922H1
RefSeq (mRNA)
NM_001145166 NM_001145167 NM_005788
NM_133740
RefSeq (protein)
NP_001138638 NP_001138639 NP_005779
NP_598501
Location (UCSC)
Chr 11: 20.39 – 20.51 Mb
Chr 7: 49.43 – 49.51 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Protein arginine N-methyltransferase 3 is an enzyme that in humans is encoded by the PRMT3 gene.[5][6]
^ abcGRCh38: Ensembl release 89: ENSG00000185238 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000030505 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Tang J, Gary JD, Clarke S, Herschman HR (July 1998). "PRMT 3, a type I protein arginine N-methyltransferase that differs from PRMT1 in its oligomerization, subcellular localization, substrate specificity, and regulation". The Journal of Biological Chemistry. 273 (27): 16935–45. doi:10.1074/jbc.273.27.16935. PMID 9642256.
^"Entrez Gene: PRMT3 protein arginine methyltransferase 3".
N-methyltransferase 3 is an enzyme that in humans is encoded by the PRMT3 gene. PRMT3 has been shown to interact with RPS2. GRCh38: Ensembl release 89:...
specific TF according to literature or domain structure – No motif [742] PRMT3 ENSG00000185238 C2H2 ZF Likely sequence specific TF according to literature...
gene dispersed through the genome. RPS2 has been shown to interact with PRMT3. GRCh38: Ensembl release 89: ENSG00000140988 – Ensembl, May 2017 GRCm38:...
at arginine residues on histone tails. The first type of PRMTs (PRMT1, PRMT3, CARM1⧸PRMT4, and Rmt1⧸Hmt1) produce monomethylarginine and asymmetric dimethylarginine...
protein arginine methyltransferases (PRMTs): Type I PRMTs (PRMT1, PRMT2, PRMT3, PRMT4, PRMT6, and PRMT8) attach two methyl groups to a single terminal...
and in vitro methylation by protein arginine methyltransferases PRMT1 and PRMT3". J. Biol. Chem. 274 (19): 13229–34. doi:10.1074/jbc.274.19.13229. PMID 10224081...
"Crystal structure of the conserved core of protein arginine methyltransferase PRMT3". EMBO J. 19 (14): 3509–19. doi:10.1093/emboj/19.14.3509. PMC 313989. PMID 10899106...
tumor suppressor interacts with protein arginine N-methyltransferase 3 (PRMT3) and inhibits its ability to methylate substrates in vitro and in vivo"...