40S ribosomal protein S2 information

RPS2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4UG0, 4V6X, 5A2Q, 5AJ0, 5FLX, 4D61, 4D5L, 4UJD, 4UJE, 4UJC
Identifiers
Aliases	RPS2, LLREP3, S2, ribosomal protein S2
External IDs	OMIM: 603624; MGI: 105110; HomoloGene: 37714; GeneCards: RPS2; OMA:RPS2 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	1,964,841 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	24,940,903 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; right uterine tube; ; right ovary; ; body of pancreas; ; left ovary; ; ventricular zone; ; mucosa of transverse colon; ; ganglionic eminence; ; granulocyte; ; zone of skin;
	Top expressed in
	ventricular zone; ; lip; ; esophagus; ; ovary; ; zone of skin; ; lens; ; ganglionic eminence; ; ileum; ; quadriceps femoris muscle; ; uterus;
	More reference expression data
	n/a
Gene ontology
Molecular function	structural constituent of ribosome; protein binding; enzyme binding; fibroblast growth factor binding; mRNA binding; RNA binding; cadherin binding;
Cellular component	cytosol; ribosome; membrane; focal adhesion; cytosolic small ribosomal subunit; nucleolus; small ribosomal subunit; extracellular exosome; nucleus; nucleoplasm; synapse;
Biological process	viral transcription; SRP-dependent cotranslational protein targeting to membrane; translational initiation; positive regulation of transferase activity; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; protein biosynthesis; rRNA processing; protein methylation; positive regulation of ubiquitin-protein transferase activity; cellular response to interleukin-4;
	Sources:Amigo / QuickGO
Orthologs
	6187
	16898
	ENSG00000140988
	ENSMUSG00000044533
	P15880
	P25444
	NM_002952
	NM_008503
	NP_002943
	NP_032529
	Wikidata
View/Edit Human	View/Edit Mouse

The RPS2 gene is the gene which, in humans, encodes the 40S ribosomal protein S2.^[5]^[6]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S5P family of ribosomal proteins. It is located in the cytoplasm. This gene shares sequence similarity with mouse LLRep3. It is co-transcribed with the small nucleolar RNA gene U64, which is located in its third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000140988 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000044533 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Kenmochi N, Kawaguchi T, Rozen S, Davis E, Goodman N, Hudson TJ, Tanaka T, Page DC (Aug 1998). "A map of 75 human ribosomal protein genes". Genome Res. 8 (5): 509–23. doi:10.1101/gr.8.5.509. PMID 9582194.
^ ^a ^b "Entrez Gene: RPS2 ribosomal protein S2".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000140988 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000044533 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9582194-5] Kenmochi N, Kawaguchi T, Rozen S, Davis E, Goodman N, Hudson TJ, Tanaka T, Page DC (Aug 1998). "A map of 75 human ribosomal protein genes". Genome Res. 8 (5): 509–23. doi:10.1101/gr.8.5.509. PMID 9582194.

[entrez-6] "Entrez Gene: RPS2 ribosomal protein S2".

40S ribosomal protein S2 information

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