The PER3 gene encodes the period circadian protein homolog 3 protein in humans.[5] PER3 is a paralog to the PER1 and PER2 genes. It is a circadian gene associated with delayed sleep phase syndrome in humans.[6]
^ abcGRCh38: Ensembl release 89: ENSG00000049246 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000028957 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Shearman LP, Zylka MJ, Weaver DR, Kolakowski LF, Reppert SM (December 1997). "Two period homologs: circadian expression and photic regulation in the suprachiasmatic nuclei". Neuron. 19 (6): 1261–9. doi:10.1016/S0896-6273(00)80417-1. PMID 9427249. S2CID 10059149.
^Cite error: The named reference Archer, 2003 was invoked but never defined (see the help page).
growing body of evidence suggests that the problem is associated with the hPer3 (human period 3) gene and CRY1 gene. For people who may have a circadian...
Light effects on circadian rhythm Light in school buildings PER1, PER2, and PER3: the period family genes Photosensitive ganglion cell: part of the eye which...
mammalian period gene PER1 in mice and humans. They also discovered PER2, PER3, and the mammalian homolog of the Drosophila gene timeless. They found that...
known homologs for the period gene in Drosophila, namely per1, per2, and per3. As per and cry are transcribed and translated into PER and CRY, the proteins...
have been identified as the causes of these sleep traits, including PER2, PER3, CRY2, CRY1. Other Mendelian genes that are not known to play a core role...
target genes such as the core clock genes 'period' genes (PER1, PER2, and PER3) and two cryptochrome genes (CRY1 and CRY2). Negative feedback is achieved...
via their PAS domains. That activator complex regulates Per1, Per2, and Per3 which all have PAS domains that are used to bind to cryptochromes 1 and 2...
double-knockout animals are placed in constant conditions. A third PER gene, mPer3, does not have a critical role in the maintenance of the core clock feedback...
died from a variety of causes, there was partial methylation at the PER2, PER3, CRY1, and TIM promoters which are important genes in controlling the circadian...
rs2304669; PER3: rs2640908, rs172933, rs2859390, rs228669. When the dominant genetic model was tested, their data showed that only SNP rs2640908 in PER3 gene...
periodically binds to and phosphorylates the PER proteins (PER1, PER2, and PER3), which form heterodimers with each other and interact with CRY1 and CRY2...
and Hitoshi Okamura to discover the mammalian period genes Per1, Per2, and Per3. They also discovered the mammalian homolog of the Drosophila gene Timeless...
dawn and is followed by increases in the levels of mPer3 and then by mPer2. mPer1 peaks at CT 4-6, mPer3 at CT 4 and 8 and mPer2 at CT 8. mPer1 is necessary...
lengthening effects. Furthermore, in humans, the P415A and H417R mutations in PER3 have been shown to destabilize the protein. These mutations have been shown...
Weaver, David (May 2001). "Differential Functions of mPer1, mPer2, and mPer3 in the SCN Circadian Clock". Neuron. 30 (2): 525–536. doi:10.1016/S0896-6273(01)00302-6...
tropicalis) PER1 (Equus caballus) PER1 (Macaca mulatta) PER1 (Sus scrofa) PER2 PER3 The human PER1 gene is located on chromosome 17 at the following location:...
duplication, of the period gene in mammals listed as mPer1, mPer2, and mPer3. There are also two paralogs of cryptochrome in mammals. PER and CRY proteins...
(CE)). Hong Kong: ARUP. Retrieved from http://www.nentnda.gov.hk/doc/pe/PER3_e.pdf 土地正義聯盟(2014年6月11日)。反東北懶人包之一:要求政府立即撤回新界東北發展計劃的十個理由。獨立媒體。2016年11月23日,取自http://www...