Osteolytic lesion at the bottom of the radius, diagnosed by a darker section that indicates a loss of bone density.
An osteolytic lesion (from the Greek words for "bone" (ὀστέον), and "to unbind" (λύειν)) is a softened section of a patient's bone formed as a symptom of specific diseases, including breast cancer and multiple myeloma. This softened area appears as a hole on X-ray scans due to decreased bone density, although many other diseases are associated with this symptom.[1] Osteolytic lesions can cause pain, increased risk of bone fracture, and spinal cord compression.[2] These lesions can be treated using biophosphonates or radiation, though new solutions are being tested in clinical trials.
^"Myeloma Bone Lesions - Lytic Bone Lesions - Bone Lesion Myeloma". Multiple Myeloma Research Foundation. Retrieved 2017-03-14.
^Matsumoto, Toshio; Kido, Shinsuke; Inoue, Daisuke; Oshima, Takashi; Abe, Masahiro (2004). "Myeloma-Bone Interaction for the Development of Myeloma Bone Disease". Journal of Bone and Mineral Research. 19 (9): 1559–1600 – via Wiley.
An osteolyticlesion (from the Greek words for "bone" (ὀστέον), and "to unbind" (λύειν)) is a softened section of a patient's bone formed as a symptom...
removing a few millimetres of bone from the very end of the bone. Osteolyticlesion Biomineralization Sanjeev Agarwal (2004). "Osteolysis - basic science...
to either osteoblastic or osteolyticlesions, reflective of the underlying mechanism of development. Typically, osteolytic metastases are more aggressive...
the lowest limit of normal, or a hemoglobin value <10g/dL Bone lesions: osteolyticlesions on skeletal radiography, CT, or PET/CT As of 2014[update] the...
osteoblastic lesions rather than osteolyticlesions seen in other cancers like breast cancer. Similarly, PC-3 and DU145 cells form osteolytic tumors. To...
spaces in a bone which are filled with blood. The term is a misnomer, as the lesion is neither an aneurysm nor a cyst. It generally presents with pain and swelling...
Barger, Rachel; et al. (June 2014). "Sotatercept in patients with osteolyticlesions of multiple myeloma". British Journal of Haematology. 165 (6): 814–823...
plasma and peripheral blood are associated with the presence of osteolytic bone lesions in patients with multiple myeloma. Due to the role of DKK1 in inflammation...
unusual. Osteolyticlesions can lead to pathological fractures. Skin: Commonly seen are a rash which varies from scaly erythematous lesions to red papules...
S, Prabhakar S, Bachhal V (March 2012). "Tuberculosis of the foot: An osteolytic variety". Indian Journal of Orthopaedics. 46 (2): 206–11. doi:10.4103/0019-5413...
characteristic brown coloration results from hemosiderin deposition into the osteolytic cysts. Hemosiderin deposition is not a distinctive feature of brown tumors;...
osteoblastic activity during remodelling and repair processes following initial osteolytic activity. This leads to a limitation of the applicability of this imaging...
hypertrophy, osteolytic bone lesions and joint contractures.: 606 This disease is caused by mutations in the CMG2 gene (ANTXR2). Skin lesion List of cutaneous...
and ilium have been involved as well. Radiologic examination evidences osteolytic areas with a lobulated framework comprising radiolucent and radiodense...
that have a radiodensity of 20 Hounsfield units (HU) or less, and are osteolytic, tend to be aneurysmal bone cysts. In contrast, intraosseous lipomas have...
that while trichomoniasis has many attributes of the model proposed (osteolytic, intra oral) several features make the assumption that it was the cause...
primary tumor, they interact with the bone microenvironment and secrete osteolytic factors capable of osteoclast formation and bone resorption. Apart from...
Global Information