Tumor-like mass resulting from the enlargement of a tuberculous lesion
A tuberculoma is a clinical manifestation of tuberculosis which conglomerates tubercles into a firm lump, and so can mimic cancer tumors of many types in medical imaging studies.[1][2] They often arise within individuals in whom a primary tuberculosis infection is not well controlled.[3] When tuberculomas arise intracranially, they represent a manifestation of CNS tuberculosis.[3] Since these are evolutions of primary complex, the tuberculomas may contain caseum or calcifications.
With the passage of time, Mycobacterium tuberculosis can transform into crystals of calcium. These can affect any organ such as the brain,[4][5] intestine,[6][7][8] ovaries,[9][10] breast,[11][12][13] lungs,[14][15] esophagus,[16] pancreas,[17] bones,[18][19] and many others. Even with guideline-directed treatment they often persist for months to years.[3]
^Pitlik SD, Fainstein V, Bodey GP (May 1984). "Tuberculosis mimicking cancer--a reminder". The American Journal of Medicine. 76 (5): 822–5. doi:10.1016/0002-9343(84)90993-8. PMID 6720729.
^Vento S, Lanzafame M (June 2011). "Tuberculosis and cancer: a complex and dangerous liaison". The Lancet. Oncology. 12 (6): 520–2. doi:10.1016/S1470-2045(11)70105-X. PMID 21624773.
^ abcLloyd N. Friedman; Martin Dedicoat; P. D. O. Davies, eds. (2020). Clinical tuberculosis (Sixth ed.). Boca Raton, FL. ISBN 978-1-351-24998-0. OCLC 1145905400.{{cite book}}: CS1 maint: location missing publisher (link)
^Chatterjee S (October 2011). "Brain tuberculomas, tubercular meningitis, and post-tubercular hydrocephalus in children". Journal of Pediatric Neurosciences. 6 (Suppl 1): S96–S100. doi:10.4103/1817-1745.85725. PMC 3208909. PMID 22069437.
^Herrick FC (April 1925). "Tuberculoma of the Caecum: Hyperplastic Tuberculosis". Annals of Surgery. 81 (4): 801–20. doi:10.1097/00000658-192504000-00009. PMC 1399989. PMID 17865239.
^Chakravartty S, Chattopadhyay G, Ray D, Choudhury CR, Mandal S (2010). "Concomitant tuberculosis and carcinoma colon: coincidence or causal nexus?". Saudi Journal of Gastroenterology. 16 (4): 292–4. doi:10.4103/1319-3767.70619. PMC 2995101. PMID 20871197.
^Kushwaha JK, Sonkar AA, Saraf A, Singh D, Gupta R (September 2011). "Jejunal adenocarcinoma: an elusive diagnosis". Indian Journal of Surgical Oncology. 2 (3): 197–201. doi:10.1007/s13193-011-0101-7. PMC 3272177. PMID 22942611.
^Elmore RG, Li AJ (December 2007). "Peritoneal tuberculosis mimicking advanced-stage epithelial ovarian cancer". Obstetrics and Gynecology. 110 (6): 1417–9. doi:10.1097/01.AOG.0000295653.32975.4a. PMID 18055741.
^Rabesalama S, Mandeville K, Raherison R, Rakoto-Ratsimba H (2011). "Isolated ovarian tuberculosis mimicking ovarian carcinoma: case report and literature review". African Journal of Infectious Diseases. 5 (1): 7–10. doi:10.4314/ajid.v5i1.66508. PMC 3497843. PMID 23878702.
^Baharoon S (July 2008). "Tuberculosis of the breast". Annals of Thoracic Medicine. 3 (3): 110–4. doi:10.4103/1817-1737.41918. PMC 2700437. PMID 19561892.
^Sen M, Gorpelioglu C, Bozer M (2009). "Isolated primary breast tuberculosis: report of three cases and review of the literature". Clinics. 64 (6): 607–10. doi:10.1590/S1807-59322009000600019. PMC 2705158. PMID 19578668.
^Akçay MN, Sağlam L, Polat P, Erdoğan F, Albayrak Y, Povoski SP (June 2007). "Mammary tuberculosis -- importance of recognition and differentiation from that of a breast malignancy: report of three cases and review of the literature". World Journal of Surgical Oncology. 5: 67. doi:10.1186/1477-7819-5-67. PMC 1910599. PMID 17577397.
^Liang HY, Li XL, Yu XS, Guan P, Yin ZH, He QC, Zhou BS, et al. (December 2009). "Facts and fiction of the relationship between preexisting tuberculosis and lung cancer risk: a systematic review". International Journal of Cancer. 125 (12): 2936–44. doi:10.1002/ijc.24636. PMID 19521963. S2CID 21083607.
^Khan AN, Al-Jahdali HH, Allen CM, Irion KL, Al Ghanem S, Koteyar SS (April 2010). "The calcified lung nodule: What does it mean?". Annals of Thoracic Medicine. 5 (2): 67–79. doi:10.4103/1817-1737.62469. PMC 2883201. PMID 20582171.
^Patnayak R, Reddy MK, Parthasarathy S, Yootla M, Reddy V, Jena A (April 2008). "Unusual presentation of esophageal tuberculosis mimicking malignancy". Saudi Journal of Gastroenterology. 14 (2): 103–4. doi:10.4103/1319-3767.39632. PMC 2702907. PMID 19568514.
^Saluja SS, Ray S, Pal S, Kukeraja M, Srivastava DN, Sahni P, Chattopadhyay TK (June 2007). "Hepatobiliary and pancreatic tuberculosis: a two decade experience". BMC Surgery. 7 (1): 10. doi:10.1186/1471-2482-7-10. PMC 1925057. PMID 17588265.
^Herzog A (September 2009). "Dangerous errors in the diagnosis and treatment of bony tuberculosis". Deutsches Ärzteblatt International. 106 (36): 573–7. doi:10.3238/arztebl.2009.0573. PMC 2770211. PMID 19890413.
^Dhillon MS, Aggarwal S, Prabhakar S, Bachhal V (March 2012). "Tuberculosis of the foot: An osteolytic variety". Indian Journal of Orthopaedics. 46 (2): 206–11. doi:10.4103/0019-5413.93683. PMC 3308663. PMID 22448060.
A tuberculoma is a clinical manifestation of tuberculosis which conglomerates tubercles into a firm lump, and so can mimic cancer tumors of many types...
into contact with Ruby while she was ill, he has developed inoperable tuberculoma and that he now only has between 12 and 18 months left to live. Tommy...
into contact with Ruby while she was ill, he has developed inoperable tuberculoma and that he has fewer than 18 months left to live. The episode ends with...
conduct medical histories. The patient is ultimately diagnosed with both a tuberculoma and rabies which is far beyond the point of treatment and the patient...
described as hallucinations arising from epilepsy or a temporal lobe tuberculoma. Others have implicated ergot poisoning, schizophrenia, delusional disorder...
defined margins - Round density within the lung parenchyma, also called a tuberculoma. Nodules included in this category are those with margins that are indistinct...
symptoms presented above. The differential diagnosis includes pituitary tuberculoma, especially in developing countries and in immumocompromised patients...
Hemiballismus or hemiballism is a basal ganglia syndrome resulting from damage to the subthalamic nucleus in the basal ganglia. Hemiballismus is a rare...
necrosis in the centre. Tubercles are also known as tuberculous nodules, or tuberculomas. The affected parts develop lesions in the form of small nodules called...
demonstrated by their high uptake of FDG (a radioactive sugar). PET-CT of a tuberculoma. Other potential forms of medical imaging of pulmonary nodules include...
cause onset of PSH. Even more obscure diseases such as intracranial tuberculoma have been seen to cause onset of paroxysmal sympathetic hyperactivity...
sober and quits drinking. Later, he is falsely diagnosed of inoperable tuberculoma due to which he demolishes his house, bids farewell to his family and...
pontine haemorrhage, ischemia, tumors, infective mass lesions such as tuberculomas, demyelinating conditions like multiple sclerosis, Arteriovenous malformation...
nervous system infections include tuberculous meningitis, intracranial tuberculomas, and spinal tuberculous arachnoiditis. Abdominal infections include gastrointestinal...
in miliary tuberculosis patients—tuberculous meningitis and cerebral tuberculomas being the most frequent. However, a majority of patients improve following...
system tuberculosis takes two major forms: tuberculous meningitis and tuberculoma. Tuberculosis may affect the central nervous system (meninges, brain...
hemorrhages, arteriovenous malformations, aneurysm, abscesses, and tuberculomas. Hallucinatory palinopsia from seizures may be secondary to a focal cortical...