Condition where an organ does not perform its expected function
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Organ dysfunction is a condition where an organ does not perform its expected function. Organ failure is organ dysfunction to such a degree that normal homeostasis cannot be maintained without external clinical intervention or life support. It is not a diagnosis. It can be classified by the cause, but when the cause is not known, it can also be classified by whether the onset is chronic or acute.
Multiple organ failure can be associated with sepsis and is often fatal. Countries such as Spain have shown a rise in mortality risk due to a large elderly population there.[1] There are tools physicians use when diagnosing multiple organ failure and when prognosing the outcome. The Sequential Organ Failure Assessment (SOFA) score[2] uses early lab values in a patient's hospitalization (within 24 hours) to predict fatal outcomes for a patient.
^Bouza C, López-Cuadrado T, Saz-Parkinson Z, Blanco J (2014). "Epidemiology and recent trends of severe sepsis in Spain: a nationwide population-based analysis (2006-2011)". BMC Infect Dis. 14 (1): 717. doi:10.1186/s12879-014-0717-7. PMC 4327809. PMID 25528662.
^Ferreira FL, Bota DP, Bross A, Mélot C, Vincent JL (2001). "Serial evaluation of the SOFA score to predict outcome in critically ill patients". JAMA. 286 (14): 1754–8. doi:10.1001/jama.286.14.1754. PMID 11594901.
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urinary tract, skin or abdominal organs. It can cause multiple organdysfunction syndrome (formerly known as multiple organ failure) and death. Frequently...
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Thijs LG (Jul 1996). "The SOFA (Sepsis-related Organ Failure Assessment) score to describe organdysfunction/failure. On behalf of the Working Group on Sepsis-Related...
failure of one or more organs or organ systems. The complications of SIRS include Acute kidney injury Shock Multiple organdysfunction syndrome The causes...
target organ in this sense) End organ damage, disease of such organs Ambulatory blood pressure § Target organ damage Sepsis § End-organdysfunction HFE hereditary...
cerebral and local autoregulation, organ system ischemia and dysfunction, and myocardial infarction. Single-organ involvement is found in approximately...
high blood pressure, large amounts of protein in the urine or other organdysfunction, and edema. If left untreated, pre-eclampsia can result in long-term...
different from multiple organdysfunction syndrome, sometimes referred to as multiple organ failure, and from multiple organ system failures, an often-fatal...
intra-abdominal pressure rises and is sustained at > 20 mmHg and there is new organdysfunction or failure. ACS is classified into three groups: Primary, secondary...
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emergency resulting from inadequate blood flow to the body's organs due to the dysfunction of the heart. Signs of inadequate blood flow include low urine...
compromise. The cumulative effects of multiple organ failure, more commonly referred to as multiple organdysfunction syndrome, also requires advanced care. Patients...
Neurogenic shock is a potentially devastating complication, leading to organdysfunction and death if not promptly recognized and treated. It is not to be...
treat acute kidney injury (AKI), but may be of benefit in multiple organdysfunction syndrome or sepsis. During hemofiltration, a patient's blood is passed...
microliter or >10% immature forms or bands qSOFA score helps predict organdysfunction outside of the intensive care unit by assessing 3 components: Systolic...
overlooked cases that could not relate physical pain to any type of organdysfunction typically could have been somatic anxiety. The Drive Theory (Zajonc...
for "pediatric patients and patients with history of cardiac or renal dysfunction." Use of a tourniquet can stall the life-threatening consequences of...
Schäfer, C. N.; Guldager, H.; Jørgensen, H. L. (January 2011). "Multi-OrganDysfunction in Bodybuilding Possibly Caused by Prolonged Hypercalcemia due to...
specific symptoms caused by pressure on an organ stuck within the hernia, potentially leading to organdysfunction. Typically, fatty tissue is the initial...
(<5%), and multiple organdysfunction with adrenal insufficiency (adrenal glands do not produce enough steroid hormones to regulate organ function). Stool...