Hemofiltration, also haemofiltration, is a renal replacement therapy which is used in the intensive care setting. It is usually used to treat acute kidney injury (AKI), but may be of benefit in multiple organ dysfunction syndrome or sepsis.[1] During hemofiltration, a patient's blood is passed through a set of tubing (a filtration circuit) via a machine to a semipermeable membrane (the filter) where waste products and water (collectively called ultrafiltrate) are removed by convection. Replacement fluid is added and the blood is returned to the patient.[2]
As in dialysis, in hemofiltration one achieves movement of solutes across a semi-permeable membrane. However, solute movement with hemofiltration is governed by convection rather than by diffusion. With hemofiltration, dialysate is not used. Instead, a positive hydrostatic pressure drives water and solutes across the filter membrane from the blood compartment to the filtrate compartment, from which it is drained. Solutes, both small and large, get dragged through the membrane at a similar rate by the flow of water that has been engendered by the hydrostatic pressure. Thus convection overcomes the reduced removal rate of larger solutes (due to their slow speed of diffusion) seen in hemodialysis.
^Cruz D, Bellomo R, Kellum J, de Cal M, Ronco C (2008). "The future of extracorporeal support". Critical Care Medicine. 36 (Suppl): S243–S252. doi:10.1097/CCM.0b013e318168e4f6. PMID 18382201. S2CID 7896249.{{cite journal}}: CS1 maint: multiple names: authors list (link)
^Hoffmann JN, Faist E (2001). "Removal of mediators by continuous hemofiltration in septic patients". World Journal of Surgery. 25 (5): 651–659. doi:10.1007/s002680020027. PMID 11369995. S2CID 10197867.
Hemofiltration, also haemofiltration, is a renal replacement therapy which is used in the intensive care setting. It is usually used to treat acute kidney...
replacement therapy includes dialysis (hemodialysis or peritoneal dialysis), hemofiltration, and hemodiafiltration, which are various ways of filtration of blood...
quantities of intravenous fluids. Other treatments may include dialysis or hemofiltration in more severe cases. Once urine output is established, sodium bicarbonate...
function, primary types of which are: Hemodialysis Peritoneal dialysis Hemofiltration Liver dialysis, a detoxification treatment for liver failure. Dialysis...
establish the underlying cause to treat the acidosis. In some situations, hemofiltration (purification of the blood) is temporarily required. In rare chronic...
extracorporeal circuitPages displaying wikidata descriptions as a fallback Hemofiltration Shils, Maurice Edward; Shike, Moshe (2006). Modern Nutrition in Health...
and they require a patient to be connected to a hemofiltration system such as Dialysis, Hemofiltration Cardiopulmonary bypass or ECMO. Other blood purification...
severe intoxication may require peritoneal dialysis, hemodialysis, or hemofiltration. Control of caffeine intake requires awareness of the caffeine content...
Peritoneal aspiration and lavage to sample fluid in the abdominal cavity Hemofiltration for acute kidney injury Mechanical ventilation to assist breathing and...
preterm newborns but not always symptomatic. Continuous dialysis or hemofiltration have proven to be the most effective treatment. Nutritional support...
severe intoxication may require peritoneal dialysis, hemodialysis, or hemofiltration. Intralipid infusion therapy is indicated in cases of imminent risk...
between the use of intermittent hemodialysis and continuous venovenous hemofiltration (CVVH) (a type of continuous hemodialysis). Among critically ill patients...
the disease on development. Exchange transfusion, hemodialysis, or hemofiltration may be used. A diet with carefully controlled levels of the amino acids...
end of the surgical case (presumably when any bleeding has stopped). Hemofiltration or ultrafiltration devices constitute the third major type of blood...
toxin. As with other extracorporeal methods, such as hemodialysis (HD), hemofiltration (HF), and hemodiafiltration (HDF), the blood travels from the patient...
Goehl H, et al. (Apr 2005). "Myoglobin clearance by super high-flux hemofiltration in a case of severe rhabdomyolysis: a case report". Critical Care. 9...
potassium is not excreted from the body. [citation needed] Hemodialysis and hemofiltration can also be used as options to remove potassium from the bloodstream...
acid property (pKa of 4.9). In severe intoxication, hemoperfusion or hemofiltration can be an effective means of hastening elimination of the drug from...
Note that this is a different process to the related technique of hemofiltration. Three primary methods are used to gain access to the blood for hemodialysis:...
with hemodialysis using a high-flux membrane, hemodiafiltration and hemofiltration. However, conventional dialysis treatment is limited in its ability...
pioneered the technique of ultrafiltration and introduced the principle of hemofiltration. Alwall is referred to as the "father of extracorporeal blood treatment...
bypass for heart surgery ECMO circuit for extracorporeal life support Hemofiltration Indwelling central or peripheral venous catheters Heparin and its low-molecular-weight...
nephrologist and university professor. He was a pioneer in the field of hemofiltration treatment and helped found an institute for drug law at the University...
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