Infection caused by pathogens that take advantage of an opportunity not normally available
Medical condition
Opportunistic infection
Chest X-ray of a patient who first had influenza and then developed Haemophilus influenzae pneumonia, presumably opportunistic
Specialty
Infectious diseases
An opportunistic infection is an infection caused by pathogens (bacteria, fungi, parasites or viruses) that take advantage of an opportunity not normally available. These opportunities can stem from a variety of sources, such as a weakened immune system (as can occur in acquired immunodeficiency syndrome or when being treated with immunosuppressive drugs, as in cancer treatment),[1] an altered microbiome (such as a disruption in gut microbiota), or breached integumentary barriers (as in penetrating trauma). Many of these pathogens do not necessarily cause disease in a healthy host that has a non-compromised immune system, and can, in some cases, act as commensals until the balance of the immune system is disrupted.[2][3] Opportunistic infections can also be attributed to pathogens which cause mild illness in healthy individuals but lead to more serious illness when given the opportunity to take advantage of an immunocompromised host.[4]
^Justiz Vaillant AA, Qurie A (2021). "Immunodeficiency". StatPearls. Treasure Island (FL): StatPearls Publishing. PMID 29763203. Retrieved 2021-03-09.
^Schroeder MR, Stephens DS (2016-09-21). "Macrolide Resistance in Streptococcus pneumoniae". Frontiers in Cellular and Infection Microbiology. 6: 98. doi:10.3389/fcimb.2016.00098. PMC 5030221. PMID 27709102.
^Achermann Y, Goldstein EJ, Coenye T, Shirtliff ME (July 2014). "Propionibacterium acnes: from commensal to opportunistic biofilm-associated implant pathogen". Clinical Microbiology Reviews. 27 (3): 419–40. doi:10.1128/CMR.00092-13. PMC 4135900. PMID 24982315.
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