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Oncolytic AAV information


Adeno-associated virus (AAV) has been researched as a viral vector in gene therapy for cancer treatment as an oncolytic virus. Currently there are not any FDA approved AAV cancer treatments, as the first FDA approved AAV treatment was approved December 2017.[1] However, there are many Oncolytic AAV applications that are in development and have been researched.

  1. ^ "First AAV-Delivered Gene Therapy for Inherited Disease Approved by FDA". Articles. ClinicalOMICs. 20 December 2017. Retrieved 2018-04-17.

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Oncolytic AAV

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(AAV) has been researched as a viral vector in gene therapy for cancer treatment as an oncolytic virus. Currently there are not any FDA approved AAV cancer...

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Oncolytic virus

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symporter (MV-NIS) Oncolytic AAV Oncovirus, virus that can cause cancer Ferguson MS, Lemoine NR, Wang Y (2012). "Systemic delivery of oncolytic viruses: hopes...

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Oncolytic adenovirus

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vector for gene therapy and also as an oncolytic virus. Of the many different viruses being explored for oncolytic potential, an adenovirus was the first...

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Viral vector

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generation of herpes simplex virus-based oncolytic immunotherapies for cancer treatment". Molecular Therapy Oncolytics. 31: 100729. doi:10.1016/j.omto.2023...

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Virotherapy

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treat diseases. There are three main branches of virotherapy: anti-cancer oncolytic viruses, viral vectors for gene therapy and viral immunotherapy. These...

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Gene therapy

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utilize adeno-associated viruses (AAVs) and lentiviruses for performing gene insertions, in vivo and ex vivo, respectively. AAVs are characterized by stabilizing...

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Astellas Pharma

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newly created Genetic Regulation Primary Focus, providing leadership for AAV pipeline advancement through commercialization, manufacturing expansion,...

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