positive regulation of transcription of nucleolar large rRNA by RNA polymerase I
angiogenesis
positive regulation of transcription by RNA polymerase II
cellular response to epidermal growth factor stimulus
negative regulation of translation
cellular response to leukemia inhibitory factor
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
4691
17975
Ensembl
ENSG00000115053
ENSMUSG00000026234
UniProt
P19338
P09405
RefSeq (mRNA)
NM_005381
NM_010880
RefSeq (protein)
NP_005372
NP_035010
Location (UCSC)
Chr 2: 231.45 – 231.48 Mb
Chr 1: 86.27 – 86.29 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Nucleolin is a protein that in humans is encoded by the NCL gene.[5][6]
^ abcGRCh38: Ensembl release 89: ENSG00000115053 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000026234 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Srivastava M, McBride OW, Fleming PJ, Pollard HB, Burns AL (Sep 1990). "Genomic organization and chromosomal localization of the human nucleolin gene". The Journal of Biological Chemistry. 265 (25): 14922–31. doi:10.1016/S0021-9258(18)77205-0. PMID 2394707.
^Erard MS, Belenguer P, Caizergues-Ferrer M, Pantaloni A, Amalric F (Aug 1988). "A major nucleolar protein, nucleolin, induces chromatin decondensation by binding to histone H1". European Journal of Biochemistry. 175 (3): 525–30. doi:10.1111/j.1432-1033.1988.tb14224.x. PMID 3409881.
Nucleolin is a protein that in humans is encoded by the NCL gene. The human NCL gene is located on chromosome 2 and consists of 14 exons with 13 introns...
Cell nucleus with DNA stained blue, and nucleolin protein in red. The nucleolin protein binds some mRNAs (e.g. mRNA for Interleukin-6). This protects...
NEURL3: encoding protein Neuralized E3 ubiquitin protein ligase 3 NCL: Nucleolin NR4A2: nuclear receptor subfamily 4, group A, member 2 OLA1: Obg-like...
disorders nidopallium caudolaterale, part of the birdbrain's nidopallium Nucleolin, a protein Nested Context Language NCAR Command Language NULL convention...
factor. Tipα enters gastric cancer cells where it binds to cell surface nucleolin, and induces the expression of vimentin. Vimentin is important in the...
by the dense fibrillar component (DFC) (that contains fibrillarin and nucleolin), which in turn is bordered by the granular component (GC) (that contains...
identified in both humans and mice: it is located in the fifth intron of the nucleolin gene in both species. Two additional snoRNAs (C/D box snoRNA U20 and the...
integration. Granzyme B can also cleave nucleophosmin, topoisomerase 1 and nucleolin to prevent viral replication. Granzyme B can cleave ICP4 from the HSV...
the extra-cellular matrix (ECM) protein nucleolin has been targeted with an aptamer that would bind nucleolin and prevent MK from being transported into...
damages. TOP1 has been shown to interact with: ASF/SF2, BTBD1, BTBD2, Nucleolin, P53, and UBE2I. Type I topoisomerase Topoisomerase GRCh38: Ensembl release...
of NPM1. NPM1 has been shown to interact with AKT1, BARD1, BRCA1, and nucleolin. linker histone H1. Nucleophosmin has multiple binding partners: rRNA...
FMRP-associated messenger ribonucleoprotein particle and identification of nucleolin and the fragile X-related proteins as components of the complex". Molecular...
(February 2003). "Centaurin-alpha 1 associates in vitro and in vivo with nucleolin". Biochemical and Biophysical Research Communications. 301 (2): 502–508...
5’-hinge of U3 and 5’-ETS may occur but is not necessary for function. Nucleolin, an abundant phosphoprotein, binds to the pre-rRNA immediately after transcription...
pseudouridylation of U97 in human 18S rRNA. U23 is encoded within intron 12 of the nucleolin gene in human, mouse, rat chicken, and Xenopus laevis. Kiss T (April 2002)...
homeostasis by maintaining the levels of multi-functional fibrillarin and nucleolin proteins. Its deficiency leads to p53 activation resulting in G2 arrest...
expression in human primary cells. MTDH has been shown to interact with: Nucleolin, NF-kB-p65 subunit, GRCh38: Ensembl release 89: ENSG00000147649 – Ensembl...
Global Information
