Nuclear membrane surrounding the nucleus in eukaryotic cells
Nuclear envelope
Human cell nucleus
Identifiers
TH
H1.00.01.2.01001
FMA
63888
Anatomical terminology
[edit on Wikidata]
The nuclear envelope, also known as the nuclear membrane,[1][a] is made up of two lipid bilayer membranes that in eukaryotic cells surround the nucleus, which encloses the genetic material.
The nuclear envelope consists of two lipid bilayer membranes: an inner nuclear membrane and an outer nuclear membrane.[4] The space between the membranes is called the perinuclear space. It is usually about 10–50 nm wide.[5][6] The outer nuclear membrane is continuous with the endoplasmic reticulum membrane.[4] The nuclear envelope has many nuclear pores that allow materials to move between the cytosol and the nucleus.[4] Intermediate filament proteins called lamins form a structure called the nuclear lamina on the inner aspect of the inner nuclear membrane and give structural support to the nucleus.[4]
^Georgia State University. "Cell Nucleus and Nuclear Envelope". gsu.edu. Archived from the original on 2018-06-18. Retrieved 2014-01-21.
^"Nuclear membrane". Biology Dictionary. Biology Online. Retrieved 7 December 2012.
^"nuclear membrane". Merriam Webster. Retrieved 7 December 2012.
^ abcdAlberts, Bruce (2002). Molecular biology of the cell (4th ed.). New York [u.a.]: Garland. p. 197. ISBN 978-0815340720.
^"Perinuclear space". Dictionary. Biology Online. Retrieved 7 December 2012.
^Berrios, Miguel, ed. (1998). Nuclear structure and function. San Diego: Academic Press. p. 4. ISBN 9780125641555.
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The nuclearenvelope, also known as the nuclear membrane, is made up of two lipid bilayer membranes that in eukaryotic cells surround the nucleus, which...
the nuclearenvelope is impermeable to large molecules, nuclear pores are required to regulate nuclear transport of molecules across the envelope. The...
prometaphase (the nucleolus and nuclear membrane disintegrating) are reversed. As chromosomes reach the cell poles, a nuclearenvelope is re-assembled around each...
anchors the nuclear pore complexes embedded in the nuclearenvelope. The nuclear lamina is associated with the inner face of the inner nuclear membrane of...
inner nuclear membrane since the two layers are fused together at numerous tiny holes called nuclear pores that perforate the nuclearenvelope. These...
A nuclear pore is a channel as part of the nuclear pore complex (NPC), a large protein complex found in the nuclearenvelope of eukaryotic cells. The nuclear...
organelle of the eukaryotic cell. It is enclosed by the nuclearenvelope, also known as the nuclear membrane. The nucleoplasm resembles the cytoplasm of...
Nesprins (nuclearenvelope spectrin repeat proteins) are a family of proteins that are found primarily in the outer nuclear membrane, as well as other...
cell nucleus. Nuclear lamins interact with inner nuclear membrane proteins to form the nuclear lamina on the interior of the nuclearenvelope. Lamins have...
Enaptin also known as nesprin-1 or synaptic nuclearenvelope protein 1 (syne-1) is an actin-binding protein that in humans that is encoded by the SYNE1...
also refers to the space between the inner and outer nuclear membranes of the nuclearenvelope, but is often called the perinuclear space.[citation needed]...
that was coined in 2000 for diseases associated with defects of the nuclearenvelope. Since the first reports of laminopathies in the late 1990s, increased...
GTPase Ran. Proteins gain entry into the nucleus through the nuclearenvelope. The nuclearenvelope consists of concentric membranes, the outer and the inner...
building blocks of the nuclear pore complex (NPC). The nuclear pore complex is a massive structure embedded in the nuclearenvelope at sites where the inner...
A nuclear groove is an invagination of the nuclearenvelope, in the longitudinal axis. It can be present in: Thyroid neoplasms: It is a characteristic...
mitosis, the nuclearenvelope disappears so that mitotic spindles can interact with the chromosomes. In closed mitosis, the nuclearenvelope does not disappear...
exiting the cell cycle. Prophase is the first stage of division. The nuclearenvelope begins to be broken down in this stage, long strands of chromatin condense...
anaphase, and telophase. Prophase: Chromatin into chromosomes, the nuclearenvelope break down, chromosomes attach to spindle fibres by their centromeres...
is permanently attached to the nuclear rim. One result is that the nuclear lamina does not provide the nuclearenvelope with enough structural support...
In cell biology, CTDNEP1 (CTD nuclearenvelope phosphate 1) is a protein coding gene involved in neural development. It is a member of DXDX(T/V) phosphatase...
irreversible actions in early mitosis, including centrosome separation, nuclearenvelope breakdown, and spindle assembly. In vertebrates, there are five cyclin...
into the nuclearenvelope as a spindle pole body. Centrioles do not exist in the MTOCs of yeast and fungi. In these organisms, the nuclearenvelope does not...
known as the nuclearenvelope, with nuclear pores that allow material to move in and out. Various tube- and sheet-like extensions of the nuclear membrane...
material may reach the nucleus by being trapped in the reassembling nuclearenvelope following mitosis. But also in non-dividing cells, research has shown...
that are located near, and continuous with, the outer layer of the nuclearenvelope. The double membrane sheets are stacked and connected through several...
membranes of the endoplasmic reticulum (which is continuous with the nuclearenvelope) Organelles (the mitochondrion in all eukaryotes and the plastid in...
processes, all of which involve mitotic chromosomes and are classified by nuclearenvelope. Amitosis can also affect the distribution of human lactic acid dehydrogenase...