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Nuclear envelope information


Nuclear envelope
Human cell nucleus
Identifiers
THH1.00.01.2.01001
FMA63888
Anatomical terminology
[edit on Wikidata]

The nuclear envelope, also known as the nuclear membrane,[1][a] is made up of two lipid bilayer membranes that in eukaryotic cells surround the nucleus, which encloses the genetic material.

The nuclear envelope consists of two lipid bilayer membranes: an inner nuclear membrane and an outer nuclear membrane.[4] The space between the membranes is called the perinuclear space. It is usually about 10–50 nm wide.[5][6] The outer nuclear membrane is continuous with the endoplasmic reticulum membrane.[4] The nuclear envelope has many nuclear pores that allow materials to move between the cytosol and the nucleus.[4] Intermediate filament proteins called lamins form a structure called the nuclear lamina on the inner aspect of the inner nuclear membrane and give structural support to the nucleus.[4]

  1. ^ Georgia State University. "Cell Nucleus and Nuclear Envelope". gsu.edu. Archived from the original on 2018-06-18. Retrieved 2014-01-21.
  2. ^ "Nuclear membrane". Biology Dictionary. Biology Online. Retrieved 7 December 2012.
  3. ^ "nuclear membrane". Merriam Webster. Retrieved 7 December 2012.
  4. ^ a b c d Alberts, Bruce (2002). Molecular biology of the cell (4th ed.). New York [u.a.]: Garland. p. 197. ISBN 978-0815340720.
  5. ^ "Perinuclear space". Dictionary. Biology Online. Retrieved 7 December 2012.
  6. ^ Berrios, Miguel, ed. (1998). Nuclear structure and function. San Diego: Academic Press. p. 4. ISBN 9780125641555.


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The nuclear envelope, also known as the nuclear membrane, is made up of two lipid bilayer membranes that in eukaryotic cells surround the nucleus, which...

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Cell nucleus

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the nuclear envelope is impermeable to large molecules, nuclear pores are required to regulate nuclear transport of molecules across the envelope. The...

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Telophase

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prometaphase (the nucleolus and nuclear membrane disintegrating) are reversed. As chromosomes reach the cell poles, a nuclear envelope is re-assembled around each...

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Nuclear lamina

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anchors the nuclear pore complexes embedded in the nuclear envelope. The nuclear lamina is associated with the inner face of the inner nuclear membrane of...

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Endomembrane system

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inner nuclear membrane since the two layers are fused together at numerous tiny holes called nuclear pores that perforate the nuclear envelope. These...

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Nuclear pore

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A nuclear pore is a channel as part of the nuclear pore complex (NPC), a large protein complex found in the nuclear envelope of eukaryotic cells. The nuclear...

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Nucleoplasm

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organelle of the eukaryotic cell. It is enclosed by the nuclear envelope, also known as the nuclear membrane. The nucleoplasm resembles the cytoplasm of...

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Mitosis

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If the nuclear envelope has broken down, a new nuclear envelope forms using the membrane vesicles of the parent cell's old nuclear envelope. The new...

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Nesprin

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Nesprins (nuclear envelope spectrin repeat proteins) are a family of proteins that are found primarily in the outer nuclear membrane, as well as other...

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Lamin

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cell nucleus. Nuclear lamins interact with inner nuclear membrane proteins to form the nuclear lamina on the interior of the nuclear envelope. Lamins have...

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Enaptin

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Enaptin also known as nesprin-1 or synaptic nuclear envelope protein 1 (syne-1) is an actin-binding protein that in humans that is encoded by the SYNE1...

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Intermembrane space

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also refers to the space between the inner and outer nuclear membranes of the nuclear envelope, but is often called the perinuclear space.[citation needed]...

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Laminopathy

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that was coined in 2000 for diseases associated with defects of the nuclear envelope. Since the first reports of laminopathies in the late 1990s, increased...

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Nuclear localization sequence

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GTPase Ran. Proteins gain entry into the nucleus through the nuclear envelope. The nuclear envelope consists of concentric membranes, the outer and the inner...

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Nucleoporin

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building blocks of the nuclear pore complex (NPC). The nuclear pore complex is a massive structure embedded in the nuclear envelope at sites where the inner...

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Nuclear groove

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A nuclear groove is an invagination of the nuclear envelope, in the longitudinal axis. It can be present in: Thyroid neoplasms: It is a characteristic...

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Trichomonas

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mitosis, the nuclear envelope disappears so that mitotic spindles can interact with the chromosomes. In closed mitosis, the nuclear envelope does not disappear...

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Cell division

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exiting the cell cycle. Prophase is the first stage of division. The nuclear envelope begins to be broken down in this stage, long strands of chromatin condense...

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PMAT

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anaphase, and telophase. Prophase: Chromatin into chromosomes, the nuclear envelope break down, chromosomes attach to spindle fibres by their centromeres...

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Progeria

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is permanently attached to the nuclear rim. One result is that the nuclear lamina does not provide the nuclear envelope with enough structural support...

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CTDNEP1

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In cell biology, CTDNEP1 (CTD nuclear envelope phosphate 1) is a protein coding gene involved in neural development. It is a member of DXDX(T/V) phosphatase...

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G2 phase

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irreversible actions in early mitosis, including centrosome separation, nuclear envelope breakdown, and spindle assembly. In vertebrates, there are five cyclin...

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Microtubule organizing center

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into the nuclear envelope as a spindle pole body. Centrioles do not exist in the MTOCs of yeast and fungi. In these organisms, the nuclear envelope does not...

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Eukaryote

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known as the nuclear envelope, with nuclear pores that allow material to move in and out. Various tube- and sheet-like extensions of the nuclear membrane...

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Lipofectamine

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material may reach the nucleus by being trapped in the reassembling nuclear envelope following mitosis. But also in non-dividing cells, research has shown...

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Endoplasmic reticulum

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that are located near, and continuous with, the outer layer of the nuclear envelope. The double membrane sheets are stacked and connected through several...

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Cellular compartment

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membranes of the endoplasmic reticulum (which is continuous with the nuclear envelope) Organelles (the mitochondrion in all eukaryotes and the plastid in...

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Amitosis

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processes, all of which involve mitotic chromosomes and are classified by nuclear envelope. Amitosis can also affect the distribution of human lactic acid dehydrogenase...

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