CTDNEP1 information

CTDNEP1
Identifiers
Aliases	CTDNEP1, DULLARD, HSA011916, NET56, CTD nuclear envelope phosphatase 1
External IDs	OMIM: 610684; MGI: 1914431; HomoloGene: 9100; GeneCards: CTDNEP1; OMA:CTDNEP1 - orthologs
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	69,881,427 bp
RNA expression pattern
	Top expressed in
	gastrocnemius muscle; ; skeletal muscle tissue; ; ganglionic eminence; ; stromal cell of endometrium; ; skin of abdomen; ; canal of the cervix; ; spleen; ; smooth muscle tissue; ; lymph node; ; uterine tube;
	Top expressed in
	muscle of thigh; ; lip; ; dentate gyrus of hippocampal formation granule cell; ; skeletal muscle tissue; ; tail of embryo; ; ventricular zone; ; ankle; ; genital tubercle; ; superior frontal gyrus; ; upper arm;
	More reference expression data
	n/a
Gene ontology
Molecular function	phosphoprotein phosphatase activity; phosphatase activity; protein serine/threonine phosphatase activity; protein binding; hydrolase activity;
Cellular component	cytoplasm; integral component of membrane; nuclear membrane; nuclear envelope; endoplasmic reticulum membrane; membrane; Nem1-Spo7 phosphatase complex; endoplasmic reticulum; nucleus; lipid droplet;
Biological process	positive regulation of triglyceride biosynthetic process; nuclear envelope organization; positive regulation of canonical Wnt signaling pathway; protein dephosphorylation; gamete generation; mitotic nuclear membrane disassembly; protein localization to nucleus; mesoderm development; dephosphorylation;
	Sources:Amigo / QuickGO
Orthologs
	23399
	67181
	n/a
	ENSMUSG00000018559
	O95476
	Q3TP92
	NM_015343; NM_001143775
	NM_026017
	NP_001137247; NP_056158
	NP_080293
	Wikidata
View/Edit Human	View/Edit Mouse

In cell biology, CTDNEP1 (CTD nuclear envelope phosphate 1) is a protein coding gene involved in neural development. It is a member of DXDX(T/V) phosphatase family and is a potential regulator of neural tube development in Xenopus. The gene promotes neural development by inhibiting Bone Morphogenetic Proteins (BMPs). The encoded protein is relatively small and only contains 244 amino acids.

^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000018559 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[refGRCm38Ensembl-1] GRCm38: Ensembl release 89: ENSMUSG00000018559 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

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