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Node of Ranvier information


Node of Ranvier
Drawing of a peripheral nerve axon (labeled "axis cylinder"), showing a node of Ranvier along with other features
Nodes of Ranvier
Details
SystemNervous system
LocationMyelinated axon of a nerve
Identifiers
Latinincisura myelini
MeSHD011901
THH2.00.06.2.03015
Anatomical terms of microanatomy
[edit on Wikidata]

In neuroscience and anatomy, nodes of Ranvier (/ˈrɑːnvi/ RAHN-vee-ay),[1][2] also known as myelin-sheath gaps, occur along a myelinated axon where the axolemma is exposed to the extracellular space. Nodes of Ranvier are uninsulated and highly enriched in ion channels, allowing them to participate in the exchange of ions required to regenerate the action potential. Nerve conduction in myelinated axons is referred to as saltatory conduction (from Latin saltus 'leap, jump') due to the manner in which the action potential seems to "jump" from one node to the next along the axon. This results in faster conduction of the action potential.

  1. ^ "node of Ranvier". Lexico UK English Dictionary. Oxford University Press. Archived from the original on October 16, 2021.
  2. ^ "node of Ranvier". Merriam-Webster.com Dictionary.

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Node of Ranvier

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In neuroscience and anatomy, nodes of Ranvier (/ˈrɑːnvieɪ/ RAHN-vee-ay), also known as myelin-sheath gaps, occur along a myelinated axon where the axolemma...

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Myelin

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called nodes of Ranvier. At the nodes of Ranvier, which are approximately one thousandth of a mm in length, the axon's membrane is bare of myelin. Myelin's...

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Axon

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myelin sheath known as nodes of Ranvier occur at evenly spaced intervals. The myelination enables an especially rapid mode of electrical impulse propagation...

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Saltatory conduction

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Node of Ranvier Axon terminal Schwann cell Myelin sheath In neuroscience, saltatory conduction (from Latin saltus 'leap, jump') is the propagation of...

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Action potential

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at one node of Ranvier provokes another action potential at the next node; this apparent "hopping" of the action potential from node to node is known...

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Node

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parameterized Lymph node, an immune system organ used to store white blood cells Node of Ranvier, periodic gaps in the insulating myelin sheaths of myelinated...

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Oligodendrocyte progenitor cell

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along unmyelinated axons as well as along myelinated axons, engulfing nodes of Ranvier. Recently, OPCs have been shown to reside in close contact with NG2-expressing...

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Chronic inflammatory demyelinating polyneuropathy

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polyneuropathy. Some variants of CIDP present autoimmunity against proteins of the node of Ranvier. These variants comprise a subgroup of inflammatory neuropathies...

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Schwann cell

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cells. Dendrite Soma Axon Nucleus Node of Ranvier Axon terminal Schwann cell Myelin sheath Schwann cells are a variety of glial cells that keep peripheral...

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SCN8A

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each node of Ranvier. The channels are highly concentrated in sensory and motor axons in the peripheral nervous system and cluster at the nodes in the...

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Pacinian corpuscle

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Ranvier's node can reach certain threshold, triggering nerve impulses or action potentials at the first node of Ranvier. The first Ranvier's node of the...

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Axon terminal

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synapses must be active at the same time. Dendrite Soma Axon Nucleus Node of Ranvier Axon terminal Schwann cell Myelin sheath Historically, calcium-sensitive...

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Outline of the human nervous system

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Oligodendrocyte (CNS) vs Schwann cell (PNS) Dendrite Soma Axon Nucleus Node of Ranvier Axon terminal Schwann cell Myelin sheath A neuron (also known as a...

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Myelinogenesis

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strengthen myelin membranes internally. In concert with the formation of axonal nodes of Ranvier, the myelin sheath's edges form paranodal loops. The basic helix–loop–helix...

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Acute motor axonal neuropathy

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motor axonal degeneration with antibody-mediated attacks of motor nerves and nodes of Ranvier.[citation needed] A link to Campylobacter jejuni was suspected...

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Nervous system

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contains two main categories or types of cells: neurons and glial cells. Dendrite Soma Axon Nucleus Node of Ranvier Axon terminal Schwann cell Myelin sheath...

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Antiganglioside antibodies

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neuropathy while high titers of anti-GM1 were more frequent indicating that GD1a possibly targets the axolemma and nodes of Ranvier most of the Ab+ patients had...

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Mechanoreceptor

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of action potentials (nerve impulses) are triggered at the first node of Ranvier of the sensory neuron. Once threshold is reached, the magnitude of the...

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Axon hillock

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gaps in the insulation (nodes of Ranvier), which boost the signal strength. As the action potential reaches a node of Ranvier, it depolarises the cell...

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Pathophysiology of multiple sclerosis

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Soma Axon Nucleus Node of Ranvier Axon terminal Schwann cell Myelin sheath Multiple sclerosis is an inflammatory demyelinating disease of the CNS in which...

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Tetraethylammonium bromide

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channels of the node of Ranvier." J. Gen. Physiol. 59 388-400. L. O. Randall, W. G. Peterson and G. Lehmann (1949). "The ganglionic blocking actions of thiophanium...

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List of human anatomical parts named after people

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Purkinje Purkinje fibres – Jan E. Purkinje Pimenta's Point Node of Ranvier – Louis-Antoine Ranvier Rathke's pouch – Martin Heinrich Rathke Reichert cartilage – Karl...

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