Axon terminals (also called synaptic boutons, presynaptic terminals, or end-feet) are distal terminations of the branches of an axon. An axon, also called a nerve fiber, is a long, slender projection of a nerve cell that conducts electrical impulses called action potentials away from the neuron's cell body to transmit those impulses to other neurons, muscle cells, or glands. Most presynaptic terminals in the central nervous system are formed along the axons (en-passant boutons), not at their ends (terminal boutons).
Functionally, the axon terminal converts an electrical signal into a chemical signal. When an action potential arrives at an axon terminal (A), the neurotransmitter is released and diffuses across the synaptic cleft. If the postsynaptic cell (B) is also a neuron, neurotransmitter receptors generate a small electrical current that changes the postsynaptic potential. If the postsynaptic cell (B) is a muscle cell (neuromuscular junction), it contracts.
Axonterminals (also called synaptic boutons, presynaptic terminals, or end-feet) are distal terminations of the branches of an axon. An axon, also called...
An axon (from Greek ἄξων áxōn, axis) or nerve fiber (or nerve fibre: see spelling differences) is a long, slender projection of a nerve cell, or neuron...
as small-scale axonterminal arbor pruning. Axons extend short axonterminal arbors toward neurons within a target area. Certain terminal arbors are pruned...
region can also receive input from other neurons. The axonterminal is found at the end of the axon farthest from the soma and contains synapses. Synaptic...
which signaling molecules called neurotransmitters are released by the axonterminal of a neuron (the presynaptic neuron), and bind to and react with the...
inhibitory neurotransmitter, like GABA, acts on GABA receptors on the axonterminal. Or when endocannabinoids act as retrograde messengers by binding to...
structure and function. The presynaptic axonterminal, or synaptic bouton, is a specialized area within the axon of the presynaptic cell that contains neurotransmitters...
of approximately 20% of an axonterminal's neurotransmitter load. Neurotransmitters are synthesized in the axonterminal where they are stored in vesicles...
the cysteine residues of SNAP-25. As an action potential reaches the axonterminal, depolarization events stimulate the opening of voltage-gated calcium...
body toward the next neuron. The bulb-like end of the axon, called the axonterminal, is separated from the dendrite of the following neuron by a small gap...
depolarization continues from the axon hillock down the axon. The surge of depolarization traveling from the axon hillock to the axonterminal is known as an action...
Neurotransmitters (chemicals) are packaged into vesicles that cluster beneath the axonterminal membrane on the presynaptic side of a synapse in a process called endocytosis...
the furthest end, the axon loses its insulation and begins to branch into several axonterminals. These presynaptic terminals, or synaptic boutons, are...
(called action potentials) pass along the axon. The myelinated axon can be likened to an electrical wire (the axon) with insulating material (myelin) around...
vesicles in axonterminals. Dopamine release from vesicles is triggered by action potential propagation-induced membrane depolarization. The axons of dopamine...
axon refers to conduction opposite of the normal (orthodromic) direction. That is, it refers to conduction along the axon away from the axonterminal(s)...
neurotransmitter used in skeletal muscle contraction) is released from the axonterminal of the nerve cell when an action potential reaches the microscopic junction...
motor loop. Dopaminergic neurons of this pathway release dopamine from axonterminals that synapse onto GABAergic medium spiny neurons (MSNs), also known...
Oligodendrocyte (CNS) vs Schwann cell (PNS) Dendrite Soma Axon Nucleus Node of Ranvier Axonterminal Schwann cell Myelin sheath A neuron (also known as a neurone...
fields. The amacrine cells also introduce lateral inhibition to the axonterminal, serving various visual functions including efficient signal transduction...
neurotransmitter transporter located along the plasma membrane of an axonterminal (i.e., the pre-synaptic neuron at a synapse) or glial cell after it...
immunostaining. The name comes from the specific shape of their axon arbors, with the terminals forming distinct arrays called "cartridges". The cartridges...
their axonterminal knobs, which is received by glutamate receptors on the lower motor neurons: from there, acetylcholine is released from the axon terminal...
the largest in the brain. The related endbulb of Held is also a large axonterminal smaller synapse (15-30 μm in diameter) found in other auditory brainstem...
types of cells: neurons and glial cells. Dendrite Soma Axon Nucleus Node of Ranvier Axonterminal Schwann cell Myelin sheath The nervous system is defined...