Myelination of a peripheral nerve by a Schwann cell
Myelinogenesis is the formation and development of myelin sheaths in the nervous system, typically initiated in late prenatal neurodevelopment and continuing throughout postnatal development.[1] Myelinogenesis continues throughout the lifespan to support learning and memory via neural circuit plasticity as well as remyelination following injury.[2] Successful myelination of axons increases action potential speed by enabling saltatory conduction, which is essential for timely signal conduction between spatially separate brain regions, as well as provides metabolic support to neurons.[3]
^Eilam, R.; Bar-Lev, D.D.; Levin-Zaidman, S.; Tsoory, M.; LoPresti, P.; Sela, M.; Arnon, R.; Aharoni, R. (2014). "Oligodendrogenesis and myelinogenesis during postnatal development effect of glatiramer acetate". Glia. 62 (4): 649–665. doi:10.1002/glia.22632. PMID 24481644. S2CID 25559134.
^Williamson JM, Lyons DA (2018). "Myelin Dynamics Throughout Life: An Ever-Changing Landscape?". Front Cell Neurosci. 12: 424. doi:10.3389/fncel.2018.00424. PMC 6252314. PMID 30510502.
proteolipid protein (PLP). Myelinogenesis thus encompasses the process of transition between phases 3 and 4. Upon initiation of myelinogenesis, each pioneer process...
neuropathologist. He is mainly remembered today for his research of myelinogenesis. Born in Zwickau, he received his education at the University of Leipzig...
NI-35 and NOGO. PTEN Muscle LIM protein Microtubule detyrosination Myelinogenesis Magnetic field Magnetic nanoparticles Neuroprotection Regenerative medicine...
PDGFRA and CSPG4. OPCs play a critical role in developmental and adult myelinogenesis. They give rise to oligodendrocytes, which then wrap around axons and...
of the proteins in neural tissue, particularly those formed during myelinogenesis, and how they change throughout the course of development. At the University...
of myelin. The process of generating myelin is called myelination or myelinogenesis. In the CNS, oligodendrocyte progenitor cells (OPCs) differentiate into...
system processes (regulatory T cell biology) and consequent changes in myelinogenesis may increase postpartum psychosis risk. Aberrant steroid hormone–dependent...
Methylation and phosphorylation of MBP are active during the process of myelinogenesis. In early CNS development of the embryo, MBP deimination plays a major...
protein locus in Pelizaeus-Merzbacher disease leads to disruption of myelinogenesis". Biol. Chem. Hoppe-Seyler. 371 (12): 1175–83. doi:10.1515/bchm3.1990...
a central role in brain very long-chain fatty acids metabolism and myelinogenesis. The conversion of long chain fatty acids into long chain acyl-CoAs...
due to parallel pathways for myelination during the initial stages of myelinogenesis. Deficiency of AspA lowers acetyl coenzyme A (CoA) expression in cells...
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