Global InformationThromboregulation information
Thromboregulation is the series of mechanisms in how a primary clot is regulated. These mechanisms include, competitive inhibition or negative feedback. It includes primary hemostasis, which is the process of how blood platelets adhere to the endothelium of an injured blood vessel.[1][2] Platelet aggregation is fundamental to repair vascular damage and the initiation of the blood thrombus formation. The elimination of clots is also part of thromboregulation. Failure in platelet clot regulation may cause hemorrhage or thrombosis. Substances called thromboregulators control every part of these events.[3]
- ^ Marcus, Aaron; Safier, Lenore (April 1993). "Thromboregulation: multicellular modulation of platelet reactivity in hemostasis and thrombosis". The FASEB Journal. 7 (6): 516–522. doi:10.1096/fasebj.7.6.8472890. PMID 8472890. S2CID 43022341.
- ^ Ruiz Argüelles, Guillermo J. (2009). Fundamentos de Hematología (in Spanish) (4 ed.). Editorial Médica Panamericana.
- ^ Brass, Lawrence (September 2003). "Thrombin and Platelet activation". Chest. 125 (3 Suppl): 18S–25S. doi:10.1378/chest.124.3_suppl.18S. PMID 12970120.