phospholipase C-activating G protein-coupled receptor signaling pathway
bombesin receptor signaling pathway
signal transduction
G protein-coupled receptor signaling pathway
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
4829
18101
Ensembl
ENSG00000135577
ENSMUSG00000019865
UniProt
P28336
O54799
RefSeq (mRNA)
NM_002511 NM_001324307 NM_001324308
NM_008703
RefSeq (protein)
NP_001311236 NP_001311237 NP_002502
NP_032729
Location (UCSC)
Chr 6: 142.06 – 142.15 Mb
n/a
PubMed search
[2]
[3]
Wikidata
View/Edit Human
View/Edit Mouse
The neuromedin B receptor (NMBR), now known as BB1[4] is a G protein-coupled receptor whose endogenous ligand is neuromedin B.[5] In humans, this protein is encoded by the NMBR gene.
Neuromedin B receptor binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and for gastrointestinal epithelial tissue.[6]
^ abcGRCh38: Ensembl release 89: ENSG00000135577 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Bombesin Receptors: BB1". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Archived from the original on 2013-10-04. Retrieved 2007-10-25.
^Benya RV, Kusui T, Pradhan TK, Battey JF, Jensen RT (1995). "Expression and characterization of cloned human bombesin receptors". Mol. Pharmacol. 47 (1): 10–20. PMID 7838118.
^"Entrez Gene: NMBR neuromedin B receptor".
and 22 Related for: Neuromedin B receptor information
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