Developmental precursor to the central nervous system
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Neural tube
Transverse section of half of a chick embryo of forty-five hours' incubation. The dorsal (back) surface of the embryo is toward the top of this page, while the ventral (front) surface is toward the bottom. (Neural tube is in green.)
Chick embryo of thirty-three hours' incubation, viewed from the dorsal aspect (30x magnification)
Details
Carnegie stage
10
Precursor
Neural groove
Gives rise to
Central nervous system (brain and spinal cord)
Identifiers
Latin
tubus neuralis, tuba neuralis
MeSH
D054259
TE
tube_by_E5.14.1.0.0.0.1 E5.14.1.0.0.0.1
Anatomical terminology
[edit on Wikidata]
In the developing chordate (including vertebrates), the neural tube is the embryonic precursor to the central nervous system, which is made up of the brain and spinal cord. The neural groove gradually deepens as the neural fold become elevated, and ultimately the folds meet and coalesce in the middle line and convert the groove into the closed neural tube. In humans, neural tube closure usually occurs by the fourth week of pregnancy (the 28th day after conception).
vertebrates), the neuraltube is the embryonic precursor to the central nervous system, which is made up of the brain and spinal cord. The neural groove gradually...
Neuraltube defects (NTDs) are a group of birth defects in which an opening in the spine or cranium remains from early in human development. In the third...
vertebrate embryos, which includes the transformation of the neural plate into the neuraltube. The embryo at this stage is termed the neurula. The process...
the neural folds, converge at the dorsal midline to form the neuraltube. Subsequently, neural crest cells from the roof plate of the neuraltube undergo...
The ends of the neural plate, known as the neural folds, push the ends of the plate up and together, folding into the neuraltube, a structure critical...
within the neuraltube. SHH and BMP gradients in the vertebrate neuraltube Ectopic floor plate formation Ventral neural domains in neuraltube Sonic hedgehog...
cephalic disorder that results from a neuraltube defect that occurs when the rostral (head) end of the neuraltube fails to close, usually between the...
types of neuraltube defects, spina bifida occulta is not associated with increased AFP, a common screening tool used to detect neuraltube defects in...
humans, the neural folds are responsible for the formation of the anterior end of the neuraltube. The neural folds are derived from the neural plate, a...
neural plate, which invaginates to form the neuraltube and neural crest. The surface ectoderm gives rise to most epithelial tissues, and the neural plate...
formation of the neural plate (neurulation), synchronizing the development of the neuraltube. On the ventral aspect of the neural groove, an axial thickening...
the wall of the closed neuraltube in early embryonic development. The neuroepithelial cells span the thickness of the tube's wall, connecting with the...
the third week of development a neuraltube is created from the ectoderm, one of the three primary germ layers. The tube forms three main vesicles during...
and migration of neural crest cells during embryonic development (though some of the genes involved also affect the neuraltube). Neural crest cells are...
called the neuraltube, whereas the future PNS appears as two strips of tissue called the neural crest, running lengthwise above the neuraltube. The sequence...
the neuraltube, and thus a transitory communication, the neurenteric canal, is established between the neuraltube and the primitive digestive tube. The...
the neuraltube, and thus a transitory communication, the neurenteric canal, is established between the neuraltube and the primitive digestive tube. The...
fissure the blood vessels enter the eye. Several layers such as the neuraltube, neural crest, surface ectoderm, and mesoderm contribute to the development...
mesoderm at either side of the neuraltube is called paraxial mesoderm. It is distinct from the mesoderm underneath the neuraltube, which is called the chordamesoderm...
Neuroectoderm (or neural ectoderm or neuraltube epithelium) consists of cells derived from the ectoderm. Formation of the neuroectoderm is the first step...
used as a supplement by women during pregnancy to reduce the risk of neuraltube defects (NTDs) in the baby. Low levels in early pregnancy are believed...
the formation of the neuraltube, and establishes the anterior-posterior body axis. The notochord extends beneath the neuraltube from the head to the...
the neuraltube in vertebrates, which eventually give rise to the brain. Vesicle formation begins shortly after the rostral closure of the neuraltube, at...
patient as either high-risk or low-risk for chromosomal abnormalities (and neuraltube defects). The term "multiple-marker screening test" is sometimes used...
into a closed tube called the neuraltube. The formation of the neuraltube is called neurulation. At this stage, the walls of the neuraltube contain proliferating...
Encephalocele is a neuraltube defect characterized by sac-like protrusions of the brain and the membranes that cover it through openings in the skull...