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Neural tube information


Neural tube
Transverse section of half of a chick embryo of forty-five hours' incubation. The dorsal (back) surface of the embryo is toward the top of this page, while the ventral (front) surface is toward the bottom. (Neural tube is in green.)
Chick embryo of thirty-three hours' incubation, viewed from the dorsal aspect (30x magnification)
Details
Carnegie stage10
PrecursorNeural groove
Gives rise toCentral nervous system (brain and spinal cord)
Identifiers
Latintubus neuralis, tuba neuralis
MeSHD054259
TEtube_by_E5.14.1.0.0.0.1 E5.14.1.0.0.0.1
Anatomical terminology
[edit on Wikidata]

In the developing chordate (including vertebrates), the neural tube is the embryonic precursor to the central nervous system, which is made up of the brain and spinal cord. The neural groove gradually deepens as the neural fold become elevated, and ultimately the folds meet and coalesce in the middle line and convert the groove into the closed neural tube. In humans, neural tube closure usually occurs by the fourth week of pregnancy (the 28th day after conception).

Stages of neural tube formation.

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Neural tube

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vertebrates), the neural tube is the embryonic precursor to the central nervous system, which is made up of the brain and spinal cord. The neural groove gradually...

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Neural tube defect

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Neural tube defects (NTDs) are a group of birth defects in which an opening in the spine or cranium remains from early in human development. In the third...

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Neurulation

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vertebrate embryos, which includes the transformation of the neural plate into the neural tube. The embryo at this stage is termed the neurula. The process...

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Neural crest

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the neural folds, converge at the dorsal midline to form the neural tube. Subsequently, neural crest cells from the roof plate of the neural tube undergo...

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Neural plate

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The ends of the neural plate, known as the neural folds, push the ends of the plate up and together, folding into the neural tube, a structure critical...

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Sonic hedgehog protein

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within the neural tube. SHH and BMP gradients in the vertebrate neural tube Ectopic floor plate formation Ventral neural domains in neural tube Sonic hedgehog...

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Anencephaly

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cephalic disorder that results from a neural tube defect that occurs when the rostral (head) end of the neural tube fails to close, usually between the...

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Spina bifida

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types of neural tube defects, spina bifida occulta is not associated with increased AFP, a common screening tool used to detect neural tube defects in...

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Neural fold

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humans, the neural folds are responsible for the formation of the anterior end of the neural tube. The neural folds are derived from the neural plate, a...

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Development of the nervous system

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neural plate, and the neural plate folds to give rise to the neural tube. This process is known as neurulation. When the tube is closed at both ends...

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Organogenesis

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the formation of the neural plate, and ultimately the neural tube in vertebrate development. The development of the neural tube will give rise to the...

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Ectoderm

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neural plate, which invaginates to form the neural tube and neural crest. The surface ectoderm gives rise to most epithelial tissues, and the neural plate...

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Notochord

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formation of the neural plate (neurulation), synchronizing the development of the neural tube. On the ventral aspect of the neural groove, an axial thickening...

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Neuroepithelial cell

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the wall of the closed neural tube in early embryonic development. The neuroepithelial cells span the thickness of the tube's wall, connecting with the...

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Diencephalon

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the third week of development a neural tube is created from the ectoderm, one of the three primary germ layers. The tube forms three main vesicles during...

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Waardenburg syndrome

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and migration of neural crest cells during embryonic development (though some of the genes involved also affect the neural tube). Neural crest cells are...

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Nervous system

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called the neural tube, whereas the future PNS appears as two strips of tissue called the neural crest, running lengthwise above the neural tube. The sequence...

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Neural groove

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the neural tube, and thus a transitory communication, the neurenteric canal, is established between the neural tube and the primitive digestive tube. The...

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Animal embryonic development

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the neural tube, and thus a transitory communication, the neurenteric canal, is established between the neural tube and the primitive digestive tube. The...

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Eye development

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fissure the blood vessels enter the eye. Several layers such as the neural tube, neural crest, surface ectoderm, and mesoderm contribute to the development...

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Somite

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mesoderm at either side of the neural tube is called paraxial mesoderm. It is distinct from the mesoderm underneath the neural tube, which is called the chordamesoderm...

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Neuroectoderm

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Neuroectoderm (or neural ectoderm or neural tube epithelium) consists of cells derived from the ectoderm. Formation of the neuroectoderm is the first step...

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Folate

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used as a supplement by women during pregnancy to reduce the risk of neural tube defects (NTDs) in the baby. Low levels in early pregnancy are believed...

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Mesoderm

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the formation of the neural tube, and establishes the anterior-posterior body axis. The notochord extends beneath the neural tube from the head to the...

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Brain vesicle

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the neural tube in vertebrates, which eventually give rise to the brain. Vesicle formation begins shortly after the rostral closure of the neural tube, at...

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Triple test

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patient as either high-risk or low-risk for chromosomal abnormalities (and neural tube defects). The term "multiple-marker screening test" is sometimes used...

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Dorsal nerve cord

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the neural plate first invaginates longitudinally to form the neural groove, whose edges (neural folds) fuse over to form a hollow neural tube. This...

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Central nervous system

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into a closed tube called the neural tube. The formation of the neural tube is called neurulation. At this stage, the walls of the neural tube contain proliferating...

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Encephalocele

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Encephalocele is a neural tube defect characterized by sac-like protrusions of the brain and the membranes that cover it through openings in the skull...

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