NPR3 information

NPR3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1JDN, 1JDP, 1YK0, 1YK1
Identifiers
Aliases	NPR3, ANP-C, ANPR-C, ANPRC, C5orf23, GUCY2B, NPR-C, NPRC, natriuretic peptide receptor 3, BOMOS
External IDs	OMIM: 108962; MGI: 97373; HomoloGene: 699; GeneCards: NPR3; OMA:NPR3 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	32,791,724 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	11,907,373 bp
RNA expression pattern
	Top expressed in
	glomerulus; ; metanephric glomerulus; ; kidney tubule; ; stromal cell of endometrium; ; renal medulla; ; kidney; ; visceral pleura; ; lower lobe of lung; ; ascending aorta; ; caput epididymis;
	Top expressed in
	atrioventricular valve; ; white adipose tissue; ; atrium; ; left lung lobe; ; right lung lobe; ; ankle; ; brown adipose tissue; ; calvaria; ; iris; ; sciatic nerve;
	More reference expression data
	n/a
Gene ontology
Molecular function	hormone binding; natriuretic peptide receptor activity; G protein-coupled peptide receptor activity; protein binding; chloride ion binding; peptide binding; protein homodimerization activity; peptide hormone binding;
Cellular component	integral component of membrane; membrane; integral component of plasma membrane; intracellular anatomical structure; extracellular exosome; protein-containing complex;
Biological process	skeletal system development; negative regulation of smooth muscle cell proliferation; positive regulation of urine volume; pancreatic juice secretion; regulation of osteoblast proliferation; regulation of blood pressure; phospholipase C-activating G protein-coupled receptor signaling pathway; positive regulation of nitric-oxide synthase activity; phosphatidylinositol-mediated signaling; osteoclast proliferation; negative regulation of adenylate cyclase activity; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; negative regulation of cold-induced thermogenesis;
	Sources:Amigo / QuickGO
Orthologs
	4883
	18162
	ENSG00000113389
	ENSMUSG00000022206
	P17342
	P70180
NM_000908; NM_001204375; NM_001204376; NM_024563; NM_001363652;
	NM_001364458; NM_001364460
	NM_001039181; NM_001286395; NM_008728
NP_000899; NP_001191304; NP_001191305; NP_001350581; NP_001351387;
	NP_001351389
	NP_001034270; NP_001273324; NP_032754
	Wikidata
View/Edit Human	View/Edit Mouse

Natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C), also known as NPR3, is an atrial natriuretic peptide receptor. In humans it is encoded by the NPR3 gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000113389 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000022206 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: NPR3 natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000113389 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000022206 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: NPR3 natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)".

NPR3 information

and 11 Related for: NPR3 information

NPR3

List of distinct cell types in the adult human body

Transition metal phosphinimide complexes

Atrial natriuretic peptide

NPRL3

DEPDC5

Atrial natriuretic peptide receptor

Phosphine imide

Phosphinimide ligands

Genetic history of the African diaspora

Phosphinoimidate