Multisystem inflammatory syndrome in children (also known as 'paediatric multisystem inflammatory syndrome', or 'paediatric inflammatory multisystem syndrome' - 'PIMS'), a rare life-threatening illness resembling Kawasaki disease that has been observed following exposure to the virus responsible for COVID-19;[1][2][3] while a similar syndrome has also been reported in adults.[4]
Kawasaki disease, a rare disease of unknown origin that affects young children, in which blood vessels become inflamed throughout the body.[5]
Systemic inflammatory response syndrome, inflammation affecting the whole body in response to an infectious or noninfectious insult.[6]
Neonatal-onset multisystem inflammatory disease, a rare genetic autoinflammatory disease which causes uncontrolled systemic inflammation from early infancy.[7]
^"Multisystem inflammatory syndrome in children and adolescents with COVID-19: Scientific brief". www.who.int. World Health Organization. Archived from the original on 15 May 2020.
^Guidance - Paediatric multisystem inflammatory syndrome temporally associated with COVID-19(PDF), The Royal College of Paediatrics and Child Health, May 2020
^"Rapid risk assessment: Paediatric inflammatory multisystem syndrome and SARS-CoV-2 infection in children". European Centre for Disease Prevention and Control. 15 May 2020. Archived from the original (PDF) on 15 May 2020.
^Morris SB, Schwartz NG, Patel P, et al. (October 2020). "Case series of multisystem inflammatory syndrome in adults associated with SARS-CoV-2 infection - United Kingdom and United States, March-August 2020". MMWR. Morbidity and Mortality Weekly Report. 69 (40): 1450–1456. doi:10.15585/mmwr.mm6940e1. PMC 7561225. PMID 33031361.
^McCrindle BW, Rowley AH, Newburger JW, Burns JC, Bolger AF, Gewitz M, Baker AL, Jackson MA, Takahashi M, Shah PB, Kobayashi T, Wu MH, Saji TT, Pahl E (2017). "Diagnosis, Treatment, and Long-Term Management of Kawasaki Disease: A Scientific Statement for Health Professionals From the American Heart Association". Circulation. 135 (17): e927–e999. doi:10.1161/CIR.0000000000000484. PMID 28356445.
^Jaffer, U; Wade, R G; Gourlay, T (2010). "Cytokines in the systemic inflammatory response syndrome: a review". HSR Proceedings in Intensive Care & Cardiovascular Anesthesia. 2 (3): 161–175. ISSN 2037-0504. PMC 3484588. PMID 23441054.
^James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
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