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Mouse models of breast cancer metastasis information


Breast cancer metastatic mouse models are experimental approaches in which mice are genetically manipulated to develop a mammary tumor leading to distant focal lesions of mammary epithelium created by metastasis. Mammary cancers in mice can be caused by genetic mutations that have been identified in human cancer. This means models can be generated based upon molecular lesions consistent with the human disease.

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Mouse models of breast cancer metastasis

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Breast cancer metastatic mouse models are experimental approaches in which mice are genetically manipulated to develop a mammary tumor leading to distant...

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Mouse model of colorectal and intestinal cancer

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oxide synthase. Mouse models of breast cancer metastasis Golovko, D; Kedrin, D; Yilmaz, ÖH; Roper, J (2015). "Colorectal cancer models for novel drug discovery"...

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Metastatic breast cancer

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treatment of brain metastases are clearly needed. breast cancer metastasis neoplasm chemotherapy Mouse models of breast cancer metastasis Phyllodes tumour...

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Metastasis

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Micrometastasis Mouse models of breast cancer metastasis Positron emission tomography (PET) Urogenital pelvic malignancy "Metastasis", Merriam–Webster...

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Mouse

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systems include mouse models of colorectal and intestinal cancer, mouse models of Down syndrome and mouse models of breast cancer metastasis. Reasons for...

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Model organism

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thaliana History of research on Caenorhabditis elegans Mouse models of breast cancer metastasis Mouse model of colorectal and intestinal cancer RefSeq - the...

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Humanized mouse

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Nude mouse SCID mouse NOG mouse NSG mouse Mouse model of colorectal and intestinal cancer Mouse models of breast cancer metastasis Knockout mouse Chuprin...

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Mouse mammary tumor virus

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MMTV promoter is used in the PyMT model system of mouse models of breast cancer metastasis. Here Py is the abbreviation of polyoma and MT is the abbreviation...

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Breast cancer

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for breast cancer in other animals Mouse models of breast cancer metastasis Metaplastic breast cancer (MBC) Vasculogenic mimicry "Breast Cancer Treatment...

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Cancer

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types of cancer in males are lung cancer, prostate cancer, colorectal cancer, and stomach cancer. In females, the most common types are breast cancer, colorectal...

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Cancer stem cell

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in metastasis and is associated with aggressive basal-like breast cancers". Proceedings of the National Academy of Sciences of the United States of America...

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Risk factors for breast cancer

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level of exercise is the cause. Carcinogen § IARC classification of carcinogens Epidemiology of breast cancer Mouse models of breast cancer metastasis Silent...

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Bioluminescence imaging

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animal. Rodent models of cancer spread can be studied through bioluminescence imaging.for e.g.Mouse models of breast cancer metastasis. Systems derived...

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Transgene

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Introgression Nucleic acid hybridization Mouse models of breast cancer metastasis "Transgene Design". Mouse Genetics Core. Washington University. Archived...

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Causes of cancer

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more than 75% risk of breast cancer and ovarian cancer. Some of the inherited genetic disorders that can cause colorectal cancer include familial adenomatous...

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Rodent

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Fum, and Phooey, mice who orbited the Moon on Apollo 17 Mouse models of breast cancer metastasis Smith, Andrew T. "Lagomorph". Encyclopædia Britannica....

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Autocrine signaling

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resulting in an autocrine loop of IL-6/STAT3 expression. Both mouse and human in vivo models of HER2-overexpressing breast cancers relied critically on this...

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Colorectal cancer

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Hong HK, Lee WY, Cho YB (February 2017). "Animal models of colorectal cancer with liver metastasis". Cancer Letters. 387: 114–120. doi:10.1016/j.canlet.2016...

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Bladder cancer

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for cancer spread (metastasis). Increase in alkaline phosphatase levels without evidence of liver disease should be evaluated for bone metastasis by a...

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Cell migration

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Chemotaxis Collective cell migration Durotaxis Endocytic cycle Mouse models of breast cancer metastasis Neurophilic Protein dynamics Mak, M.; Spill, F.; Roger...

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Animal testing on rodents

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imaging Rat Park Testing cosmetics on animals Mouse models of breast cancer metastasis "Annual Statistics of Scientific Procedures on Living Animals, Great...

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Molecular imaging

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imaging MICAD Predictive medicine Translational medicine Mouse models of breast cancer metastasis Gallagher, F.A. (2010). "An introduction to functional...

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Prostate cancer

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(May 2013). "Animal Models of Human Prostate Cancer: the Consensus Report of the New York Meeting of the Mouse Models of Human Cancers Consortium Prostate...

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Patient derived xenograft

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are models of cancer where the tissue or cells from a patient's tumor are implanted into an immunodeficient or humanized mouse. It is a form of xenotransplantation...

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Stomach cancer

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Stomach cancer, also known as gastric cancer, is a cancer that develops from the lining of the stomach. Most cases of stomach cancers are gastric carcinomas...

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Wnt signaling pathway

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metastasis of basal-like breast cancer to the lungs showed that repression of Wnt/β-catenin signaling can prevent EMT, which can inhibit metastasis....

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Colony stimulating factor 1 receptor

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receptor is also linked with the cells of MPS. Cluster of differentiation Mouse models of breast cancer metastasis Pimicotinib GRCh38: Ensembl release 89:...

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Breast cancer stem cell

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methods for breast cancer include surgery, radiotherapy and chemotherapy. Some of these treated patients experience disease relapse and metastasis. The aggressive...

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