Molecular binding is an attractive interaction between two molecules that results in a stable association in which the molecules are in close proximity to each other. It is formed when atoms or molecules bind together by sharing of electrons. It often, but not always, involves some chemical bonding.
In some cases, the associations can be quite strong—for example, the protein streptavidin and the vitamin biotin have a dissociation constant (reflecting the ratio between bound and free biotin) on the order of 10−14—and so the reactions are effectively irreversible. The result of molecular binding is sometimes the formation of a molecular complex in which the attractive forces holding the components together are generally non-covalent, and thus are normally energetically weaker than covalent bonds.
Molecular binding occurs in biological complexes (e.g., between pairs or sets of proteins, or between a protein and a small molecule ligand it binds) and also in abiologic chemical systems, e.g. as in cases of coordination polymers and coordination networks such as metal-organic frameworks.
Molecularbinding is an attractive interaction between two molecules that results in a stable association in which the molecules are in close proximity...
Cooperative binding occurs in molecularbinding systems containing more than one type, or species, of molecule and in which one of the partners is not...
Neural binding, synchronous activity of neurons and neuronal ensembles Molecularbinding, an attractive interaction between two molecules Binding (linguistics)...
differs from simple diffusion in several ways: The transport relies on molecularbinding between the cargo and the membrane-embedded channel or carrier protein...
and molecular biology, a binding site is a region on a macromolecule such as a protein that binds to another molecule with specificity. The binding partner...
that exhibit molecular recognition. One of the earliest examples of such a system are crown ethers which are capable of selectively binding specific cations...
In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic...
of an artificial molecular machine (AMM) was reported in 1994, featuring a rotaxane with a ring and two different possible binding sites. In 2016 the...
around 35% of the total weight (including water). Hemoglobin has an oxygen-binding capacity of 1.34 mL of O2 per gram, which increases the total blood oxygen...
Data from molecular docking can be used to construct new compounds that are more or less efficient at binding to a specific molecule. Molecular docking...
Molecular biology /məˈlɛkjʊlər/ is a branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including...
obtained cavity can work as a selective binding site for the templated molecule. In recent decades, the molecular imprinting technique has been developed...
aptamers are small, with a molecular weight of 6-30 kDa, in contrast to the 150 kDa size of antibodies, and contain one binding site rather than the two...
positions of critical amino acids involved in ligand binding. Carlson et al. implemented molecular dynamics simulations to identify compounds that complement...
The ABC transporters, ATP synthase (ATP)-binding cassette transporters are a transport system superfamily that is one of the largest and possibly one...
Molecular Partners AG is a clinical-stage biopharmaceutical company based in Zürich, Switzerland. The company is developing a new class of potent, specific...
The molecular mass (m) is the mass of a given molecule. The unit dalton (Da) is often used. Different molecules of the same compound may have different...
(January 1991). "Structure, function and properties of antibody binding sites". Journal of Molecular Biology. 217 (1): 133–51. doi:10.1016/0022-2836(91)90617-F...
exchanged. Therefore, covalent binding by quark interchange is expected to be the dominating mechanism of nuclear binding at small distance when the bound...
of conductive polymers, organic semiconductors and molecular electronics, for example, tight-binding-like models are applied in which the role of the atoms...
In molecular genetics, a repressor is a DNA- or RNA-binding protein that inhibits the expression of one or more genes by binding to the operator or associated...
as it will no longer possess a net surface charge (a requisite for molecularbinding to ion exchange resins). Chromatofocusing is a powerful purification...
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