MicroRNA sequencing (miRNA-seq), a type of RNA-Seq, is the use of next-generation sequencing or massively parallel high-throughput DNA sequencing to sequence microRNAs, also called miRNAs. miRNA-seq differs from other forms of RNA-seq in that input material is often enriched for small RNAs. miRNA-seq allows researchers to examine tissue-specific expression patterns, disease associations, and isoforms of miRNAs, and to discover previously uncharacterized miRNAs. Evidence that dysregulated miRNAs play a role in diseases such as cancer[1] has positioned miRNA-seq to potentially become an important tool in the future for diagnostics and prognostics as costs continue to decrease.[2] Like other miRNA profiling technologies, miRNA-Seq has both advantages (sequence-independence, coverage) and disadvantages (high cost, infrastructure requirements, run length, and potential artifacts).[3]
^Farazi, Thalia A; Spitzer, Jessica I; Morozov, Pavel; Tuschl, Thomas (2011). "miRNAs in human cancer". The Journal of Pathology. 223 (2): 102–115. doi:10.1002/path.2806. ISSN 0022-3417. PMC 3069496. PMID 21125669.
^Sandhu, S.; Garzon, R. (2011). "Potential Applications of MicroRNAs in Cancer Diagnosis, Prognosis, and Treatment". Semin Oncol. 38 (6): 781–787. doi:10.1053/j.seminoncol.2011.08.007. PMID 22082764.
^Cite error: The named reference Baker2010 was invoked but never defined (see the help page).
and 17 Related for: MicroRNA sequencing information
MicroRNAsequencing (miRNA-seq), a type of RNA-Seq, is the use of next-generation sequencing or massively parallel high-throughput DNA sequencing to sequence...
MicroRNA (miRNA) are small, single-stranded, non-coding RNA molecules containing 21 to 23 nucleotides. Found in plants, animals and some viruses, miRNAs...
next-generation sequencing applied to whole transcriptomes see: RNA-Seq and MicroRNASequencing. Methods for performing protein sequencing include: Edman...
: 366 Small RNA have been detected or sequenced using a range of techniques, including directly by MicroRNAsequencing on several sequencing platforms,...
ionic current methods and the sequencing of several DNA oligomers and micro-RNA has already been achieved. Sequencing by hybridization is a non-enzymatic...
mRNA targets with the associated alignments for the small RNA-mRNA pairs. The applications of degradome sequencing include identifying microRNA (miRNA)...
This microRNA database and microRNA targets databases is a compilation of databases and web portals and servers used for microRNAs and their targets....
MicroRNA (miRNA) biosensors are analytical devices that involve interactions between the target miRNA strands and recognition element on a detection platform...
transfer RNA (tRNA), microRNA (miRNA), small interfering RNA (siRNA), small nucleolar RNA (snoRNAs), Piwi-interacting RNA (piRNA), tRNA-derived small RNA (tsRNA)...
modifications of RNA molecules and determine the transcriptome-wide landscape of RNA modifications by means of next generation RNAsequencing, recently many...
of RNA binding, DNA-barcoded micro beads to a rubber coated glass coverslip. The microbeads are mapped to their spatial location via SOLiD sequencing. Tissue...
considered as a possible mechanism for RNA secretion from the cell, but more recently research studying microRNA secretion in human embryonic kidney cells...
repetitive sequences. With advancements in technology that could handle sequencing of the many repetitive sequences found in human DNA that were not fully...
S2CID 23728518. Ju Son D (2013). "The atypical mechanosensitive microRNA-712 derived from pre-ribosomal RNA induces endothelial inflammation and atherosclerosis"...
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