B lymphocytes are the cells of the immune system that make antibodies to invading pathogens like viruses. They form memory cells that remember the same pathogen for faster antibody production in future infections.
In immunology, a memory B cell (MBC) is a type of B lymphocyte that forms part of the adaptive immune system. These cells develop within germinal centers of the secondary lymphoid organs. Memory B cells circulate in the blood stream in a quiescent state, sometimes for decades.[1] Their function is to memorize the characteristics of the antigen that activated their parent B cell during initial infection such that if the memory B cell later encounters the same antigen, it triggers an accelerated and robust secondary immune response.[2][3] Memory B cells have B cell receptors (BCRs) on their cell membrane, identical to the one on their parent cell, that allow them to recognize antigen and mount a specific antibody response.[4]
^Crotty S, Felgner P, Davies H, Glidewell J, Villarreal L, Ahmed R (November 2003). "Cutting edge: long-term B cell memory in humans after smallpox vaccination". Journal of Immunology. 171 (10): 4969–4973. doi:10.4049/jimmunol.171.10.4969. PMID 14607890.
^Weisel F, Shlomchik M (April 2017). "Memory B Cells of Mice and Humans". Annual Review of Immunology. 35 (1): 255–284. doi:10.1146/annurev-immunol-041015-055531. PMID 28142324.
^Seifert M, Küppers R (December 2016). "Human memory B cells". Leukemia. 30 (12): 2283–2292. doi:10.1038/leu.2016.226. PMID 27499139. S2CID 28936531.
^Kurosaki T, Kometani K, Ise W (March 2015). "Memory B cells". Nature Reviews. Immunology. 15 (3): 149–159. doi:10.1038/nri3802. PMID 25677494. S2CID 20825732.
In immunology, a memoryBcell (MBC) is a type of B lymphocyte that forms part of the adaptive immune system. These cells develop within germinal centers...
When a naïve or memoryBcell is activated by an antigen, it proliferates and differentiates into an antibody-secreting effector cell, known as a plasmablast...
naive Bcell either becomes a memoryBcell or a plasma cell that secretes antibodies specific to the antigen that was originally bound. Plasma cells do...
Within the immune system, Follicular Bcells (FO Bcells) are a type of Bcell that reside in primary and secondary lymphoid follicles (containing germinal...
brain. MemoryBcell, an antibody producing cellMemory T cell, an infection fighting cellMemorycell (computing), a building block of computer memory and...
cells and durable memoryBcells. There are several key differences between naive Bcells and GC Bcells. Naive Bcells do not undergo lots of cell division...
immune memory.[citation needed] After the inflammatory immune response to danger-associated antigen, some of the antigen-specific T cells and Bcells persist...
infection, long-lived memoryBcells are generated, which remain in the body and protect from subsequent infections. These memoryBcells respond to specific...
cells, the CD4+ T cells, function as "helper cells". Unlike CD8+ killer T cells, the CD4+ helper T (TH) cells function by further activating memoryB...
into the addition of three different methyl subgroups (naïve B-cell-like, memoryB-cell-like, and intermediate), which impact how much that DNA sequence...
plasma cells and memoryBcells. Adhesion between FDCs and Bcells is mediated by ICAM-1 (CD54)–LFA-1 (CD11a) and VCAM–VLA-4 molecules. Activated B-cells with...
center-dependent memoryBcells capable of quick immune re-activation in the future if ever the same antigen is re-encountered. TFH cells are also thought...
to Bcell receptors that inhibits cell division. Because the infant's immune system is not stimulated and Bcell division is inhibited, few memoryB cells...
cell, all progeny (offspring) of that cell inherit genes that encode the same receptor specificity, including the memoryBcells and memory T cells that...
mainly a defect in the differentiation process of Bcells into memory and plasma cells. There are also T cell abnormalities in CVID including counts, percentages...
into helper T cells, memory T cells, cytotoxic T cells), Bcells (subdivided into plasma cells and memoryBcells), and natural killer cells. Historically...
Polyclonal Bcell response is a natural mode of immune response exhibited by the adaptive immune system of mammals. It ensures that a single antigen is...
induce B cells to divide rapidly, making thousands of identical clones of the Bcell. These daughter cells either become plasma cells or memorycells. The...
subtypes of Bcells, especially memoryBcells. Although cladribine is selective for Bcells, the long-term suppression of memoryBcells, which may contribute...
ISBN 978-0-443-01657-8. Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Walter P (2002). "Table 22-1, Blood Cells". Molecular Biology of the Cell (4th ed.). Garland...
two main types of flash memory, NOR flash and NAND flash, are named for the NOR and NAND logic gates. Both use the same cell design, consisting of floating...
adaptive immune system, as they have no memory, but otherwise, B1 cells perform many of the same roles as other Bcells: making antibodies against antigens...
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