Membrane vesicle trafficking in eukaryotic animal cells involves movement of biochemical signal molecules from synthesis-and-packaging locations in the Golgi body to specific release locations on the inside of the plasma membrane of the secretory cell. It takes place in the form of Golgi membrane-bound micro-sized vesicles, termed membrane vesicles (MVs).
In this process, the packed cellular products are released or secreted outside the cell, across its membrane. On the other hand, the vesicular membrane is retained and recycled by the secretory cells. This phenomenon has a major role in synaptic neurotransmission, endocrine secretion, mucous secretion, granular-product secretion by neutrophils, and other phenomena. The scientists behind this discovery were awarded Nobel prize for the year 2013.
In prokaryotic, gram-negative bacterial cells, membrane vesicle trafficking is mediated through bacterial outer membrane bounded nano-sized vesicles, called outer membrane vesicles (OMVs). In this case, however, the OMV membrane is secreted as well, along with OMV-contents to outside the secretion-active bacterium. This different phenomenon has a major role in host–pathogen interactions, endotoxic shock in patients, invasion and infection of animals or plants, inter-species bacterial competition, quorum sensing, exocytosis, and other areas.
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Membranevesicletrafficking in eukaryotic animal cells involves movement of biochemical signal molecules from synthesis-and-packaging locations in the...
Outer membranevesicles (OMVs) are vesicles released from the outer membranes of Gram-negative bacteria. While Gram-positive bacteria release vesicles as...
competing with other microbes for nutrition, etc. This finding of membranevesicletrafficking occurring at the host–pathogen interface also dispels the myth...
unforeseen dimension to the well-known eukaryote process of membranevesicletrafficking, which is quite active at the host–pathogen interface. They may...
cholesterol. Synaptic vesicles contain two classes of obligatory components: transport proteins involved in neurotransmitter uptake, and trafficking proteins that...
plasma membrane within a short time. Exocytosis in prokaryotes: Membrane vesicular exocytosis, popularly known as membranevesicletrafficking, a Nobel...
cells. Microtubules are also required for the trafficking of membranevesicles. Membranevesicletrafficking is needed for the correct positioning of several...
in the cytoplasm, it packages proteins into membrane-bound vesicles inside the cell before the vesicles are sent to their destination. It resides at...
and Thomas C. Südhof for their ground-breaking work on cell membranevesicletrafficking. Schekman was born in Saint Paul, Minnesota, to Alfred Schekman...
media related to Cell membrane. Wikiversity has learning resources about The Cell Membrane Lipids, Membranes and VesicleTrafficking – The Virtual Library...
virulence factors at host–pathogen interface, via membranevesicletrafficking as bacterial outer membranevesicles for invasion, nutrition and other cell-cell...
lifecycle of temperate bacteriophages. Host–pathogen interaction Membranevesicletrafficking Bacterial effector protein Infectious disease Law of declining...
include: the nuclear membrane, the endoplasmic reticulum, the Golgi apparatus, lysosomes, vesicles, endosomes, and plasma (cell) membrane among others. The...
rounded vesicles in the cytoplasm for intracellular trafficking. Clathrin-coated vesicles (CCVs) selectively sort cargo at the cell membrane, trans-Golgi...
deploy bacterial outer membranevesicles to translocate effector proteins and virulence factors via a membranevesicletrafficking secretory pathway, in...
attached to vesicles that contain a neurotransmitter chemical. These proteins change shape, causing the membranes of some "docked" vesicles to fuse with...
Vesicle fusion is the merging of a vesicle with other vesicles or a part of a cell membrane. In the latter case, it is the end stage of secretion from...
internalized is surrounded by an area of cell membrane, which then buds off inside the cell to form a vesicle containing the ingested materials. Endocytosis...
the plasma membrane and internal membranes have cytosolic and exoplasmic faces • This orientation is maintained during membranetrafficking – proteins...
involved in vesicletrafficking, specifically the tethering and spatial targeting of post-Golgi vesicles to the plasma membrane prior to vesicle fusion. It...
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