Mannose-6 phosphate isomerase (MPI), alternately phosphomannose isomerase (PMI) (EC 5.3.1.8) is an enzyme which facilitates the interconversion of fructose 6-phosphate (F6P) and mannose-6-phosphate (M6P). Mannose-6-phosphate isomerase may also enable the synthesis of GDP-mannose in eukaryotic organisms. M6P can be converted to F6P by mannose-6-phosphate isomerase and subsequently utilized in several metabolic pathways including glycolysis and capsular polysaccharide biosynthesis.[1] PMI is monomeric and metallodependent on zinc as a cofactor ligand.[2] PMI is inhibited by erythrose 4-phosphate, mannitol 1-phosphate, and to a lesser extent, the alpha anomer of M6P.[3]
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Mannose-6 phosphateisomerase (MPI), alternately phosphomannose isomerase (PMI) (EC 5.3.1.8) is an enzyme which facilitates the interconversion of fructose...
yields mannose, which is phosphorylated by hexokinase to generate mannose-6-phosphate. Mannose-6-phosphate is converted to fructose-6-phosphate, by the...
In biochemistry, isomerases are a general class of enzymes that convert a molecule from one isomer to another. Isomerases facilitate intramolecular rearrangements...
imaging, a medical procedure that illustrates heart function Mannosephosphateisomerase, an enzyme Mass psychogenic illness, the rapid spread of illness...
catalyzes the chemical reaction glycerone phosphate ⇌ {\displaystyle \rightleftharpoons } 2-oxopropanal + phosphate Attempts to observe reversibility of this...
key in multiple functions: Manufacture of lysosomal enzymes with a mannose-6-phosphate marker added in the cis-Golgi network. Manufacture of secreted proteins...
glyceraldehyde 3-phosphate dehydrogenase lost, glycolysis cannot proceed. D-erythrose 4-phosphate was found to be an inhibitor of phosphoglucose isomerase. Phosphoglucose...
D-mannose 6-phosphate. This enzyme belongs to the family of isomerases, specifically the phosphotransferases (phosphomutases), which transfer phosphate...
to glyceraldehyde 3-phosphate by triosephosphate isomerase or undergo reduction to glycerol 3-phosphate by glycerol 3-phosphate dehydrogenase. The glyceraldehyde...
Junop (1 February 2008). "Structure and Function of Sedoheptulose-7-phosphateIsomerase, a Critical Enzyme for Lipopolysaccharide Biosynthesis and a Target...
block of glycogen. Glucose can also be converted from bacterial xylose isomerase to fructose. In addition, glucose metabolites produce all nonessential...
(dihydroxyacetone phosphate), catalyzed by the enzyme triosephosphate isomerase, is an intermediate step in glycolysis. Stereoisomerism Merck Index, 11th...
formed from l-fucose by l-fucose isomerase and converted to L-fuculose-1-phosphate by l-fuculose kinase. l-fuculose-phosphate aldolase l-fuculosekinase Lindhorst...
Liangkun; Ding, Shaojun (2020). "Characterization of an L-Arabinose Isomerase from Bacillus velezensis and Its Application for L-Ribulose and L-Ribose...
D-mannose 6-phosphate and D-mannose 1-phosphate which is a substrate for GDP-mannose synthesis. GDP-mannose is used for synthesis of dolichol-phosphate-mannose...
catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate. Mannose 1-phosphate is a precursor to GDP-mannose necessary for the synthesis...
syndromes like: Spectrum of Genetic Disorders in Arabs, Lebanese type of mannose 6--phosphate receptor recognition defect (1984), Algerian type of spondylometaphyseal...
encoding genes for carboxylase, cellulase and xylanase enzymes, xylose isomerase, and carboxylesterase. Other genes coding for biosynthesis of peptides...
cis-trans isomerase D PPIE Peptidyl-prolyl cis-trans isomerase E PPIF Peptidyl-prolyl cis-trans isomerase F PPIG Peptidyl-prolyl cis-trans isomerase G PPIH...
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