regulation of protein localization to plasma membrane
skeletal system development
extracellular matrix organization
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
4323
17387
Ensembl
ENSG00000157227
ENSMUSG00000000957
UniProt
P50281
P53690
RefSeq (mRNA)
NM_004995
NM_008608
RefSeq (protein)
NP_004986
NP_032634
Location (UCSC)
Chr 14: 22.84 – 22.85 Mb
Chr 14: 54.67 – 54.68 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Matrix metalloproteinase-14 is an enzyme that in humans is encoded by the MMP14 gene.[5]
^ abcGRCh38: Ensembl release 89: ENSG00000157227 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000000957 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Sato H, Takino T, Okada Y, Cao J, Shinagawa A, Yamamoto E, Seiki M (Jul 1994). "A matrix metalloproteinase expressed on the surface of invasive tumour cells". Nature. 370 (6484): 61–5. Bibcode:1994Natur.370...61S. doi:10.1038/370061a0. PMID 8015608. S2CID 4275857.
Matrix metalloproteinase-14 is an enzyme that in humans is encoded by the MMP14 gene. Proteins of the matrix metalloproteinase (MMP) family are involved...
respectively. HoxA3 induces endothelial cell (EC) migration by upregulating MMP14 and uPAR. Conversely, HoxD10 and HoxA5 have the opposite effect of suppressing...
MMP-13 secreted Substrates include Col I, II, III, IV, IX, X, XIV, gelatin MMP14 MT1-MMP MMP-14, MMP-X1, MT-MMP, MT-MMP 1, MT1-MMP, MT1MMP, MTMMP1, WNCHRS...
requires proteolytic processing. A complex of membrane type 1 MMP (MT1-MMP/MMP14) and tissue inhibitor of metalloproteinase 2 recruits pro-MMP 2 from the...
"Genes of the membrane-type matrix metalloproteinase (MT-MMP) gene family, MMP14, MMP15, and MMP16, localize to human chromosomes 14, 16, and 8, respectively"...
given human umbilical cord blood. TIMP2 has been shown to interact with: MMP14 and MMP2. TIMP1, TIMP3, TIMP4 GRCh38: Ensembl release 89: ENSG00000035862...
As lumican can directly bind to and inhibit matrix metalloproteinase-14 (MMP14), lumican may limit tumor progression by preventing extracellular matrix...
human genes for membrane-type-1, -2, and -3 matrix metalloproteinases (MMP14, MMP15, and MMP16) to 14q12.2, 16q12.2-q21, and 8q21, respectively, by in...
MEN1 mutations are occasionally found in pediatric ependymomas. MMP2 and MMP14 appear to also play a role in tumor growth and progression in intracranial...
induce smooth muscle cell migration in response to PDGFB by activating MMP14. When Pcsk6 was knocked out, the intimal hyperplasia response to in vivo...
Invasion is accompanied by proteolysis of the ECM through activation of MMP14, MMP2 and MMP9 metalloproteinases. NEDD9 is involved in chemokine-induced...