Pediatric ependymomas are similar in nature to the adult form of ependymoma in that they are thought to arise from radial glial cells lining the ventricular system. However, they differ from adult ependymomas in which genes and chromosomes are most often affected, the region of the brain they are most frequently found in, and the prognosis of the patients. Children with certain hereditary diseases, such as neurofibromatosis type II (NF2), have been found to be more frequently afflicted with this class of tumors, but a firm genetic link remains to be established. Symptoms associated with the development of pediatric ependymomas are varied, much like symptoms for a number of other pediatric brain tumors including vomiting, headache, irritability, lethargy, and changes in gait. Although younger children and children with invasive tumor types generally experience less favorable outcomes, total removal of the tumors is the most conspicuous prognostic factor for both survival and relapse.
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Pediatricependymomas are similar in nature to the adult form of ependymoma in that they are thought to arise from radial glial cells lining the ventricular...
An ependymoma is a tumor that arises from the ependyma, a tissue of the central nervous system. Usually, in pediatric cases the location is intracranial...
Collaborative Ependymoma Research Network (CERN) Foundation is a nonprofit organization composed of scientists and adult and pediatric cancer researchers...
an empty lumen. They are also distinct from the pseudorosettes of an ependymoma which consist of tumor cells with glial fibrillary acidic protein (GFAP)–positive...
U (March 2000). "Sacrococcygeal extraspinal ependymomas: the role of coccygectomy". Journal of Pediatric Surgery. 35 (3): 515–518. doi:10.1016/S0022-3468(00)90228-8...
the first single-center clinical trial for recurrent medulloblastoma, ependymoma and atypical teratoid-rhabdoid tumors using the direct infusion of chemotherapy...
disease; paraneoplastic syndromes; and ependymomas. She stepped into the role of editor-in-chief of Pediatric Neurology in 2022. Prior to that, she was...
Brown-Séquard syndrome Central cord syndrome Dissociated sensory loss Ependymoma, a type of tumors that are capable of causing syringomyelia Otto Kahler...
ependymomas, and endodermal sinus tumors. Guler and Sugita separately reported cases of lung metastasis without a shunt. An estimated 3% of pediatric...
ruled out to obtain a differential diagnosis. These include extraspinal ependymoma, ependymoblastoma, neuroblastoma and rhabdomyosarcoma. Smaller SCTs with...
in the patient's care team when the diagnosis is made. Medulloblastoma Ependymoma Ewing family of tumors "primitive neuroectodermal tumor" at Dorland's...
neuroradiologic features finally distinguish astroblastoma from the common ependymoma, another frequent tumor occurring in the fourth ventricle. In general...
be multiple and are associated with increased mortality. Spinal cord ependymomas occur in 20-50% of patients but they are asymptomatic in the majority...
shown that clinically distinct subtypes of childhood medulloblastoma and ependymoma arise within different lineages of developing brain and are driven by...
been linked to the generation of oncogenic fusions in supratentorial ependymoma, chondromyxoid fibroma, and Ewing sarcoma, the latter two being bone tumours...
system (CNS) tumors such as glioblastoma multiforme, medulloblastoma, ependymoma, and choroid plexus carcinoma. Strictly speaking, the most common cause...
an arteriovenous malformation or cavernous malformation, myxopapillary ependymoma of the spinal cord, from chronic subdural hematoma, from a ventricular...
Her". New York. Retrieved August 20, 2009. Ris MD (2007). "Lessons in pediatric neuropsycho-oncology: what we have learned since Johnny Gunther". J Pediatr...
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