positive regulation of transcription by RNA polymerase II
regulation of phosphatidylinositol 3-kinase signaling
regulation of ossification
positive regulation of gene expression
positive regulation of macrophage chemotaxis
cellular response to amino acid starvation
cellular response to reactive oxygen species
stress-activated MAPK cascade
cellular response to cadmium ion
cellular response to dopamine
positive regulation of metallopeptidase activity
regulation of cellular pH
protein-containing complex assembly
cellular response to tumor necrosis factor
regulation of gene expression
cellular response to organic substance
human ageing
decidualization
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
5595
26417
Ensembl
ENSG00000102882
ENSMUSG00000063065
UniProt
P27361
Q63844
RefSeq (mRNA)
NM_001040056 NM_001109891 NM_002746
NM_011952
RefSeq (protein)
NP_001035145 NP_001103361 NP_002737
NP_036082
Location (UCSC)
Chr 16: 30.11 – 30.12 Mb
Chr 7: 126.36 – 126.36 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Mitogen-activated protein kinase 3, also known as p44MAPK and ERK1,[5] is an enzyme that in humans is encoded by the MAPK3 gene.[6]
^ abcGRCh38: Ensembl release 89: ENSG00000102882 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000063065 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Thomas, Gareth M.; Huganir, Richard L. (1 March 2004). "MAPK cascade signalling and synaptic plasticity". Nature Reviews Neuroscience. 5 (3): 173–183. doi:10.1038/nrn1346. ISSN 1471-003X. PMID 14976517. S2CID 205499891.
^García F, Zalba G, Páez G, Encío I, de Miguel C (15 May 1998). "Molecular cloning and characterization of the human p44 mitogen-activated protein kinase gene". Genomics. 50 (1): 69–78. doi:10.1006/geno.1998.5315. PMID 9628824.
known as p44MAPK and ERK1, is an enzyme that in humans is encoded by the MAPK3 gene. The protein encoded by this gene is a member of the mitogen-activated...
signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response...
(classification), a Modern pentathlon classification Feinwerkbau P44, a match pistol MAPK3, p44 mitogen-activated protein kinase P44 road (Ukraine) Papyrus 44, a biblical...
are effectors of mitogenic ras signaling and which activate the ERK1/2 (MAPK3/MAPK1) pathway, through activation of MEK1(MAP2K1) and MEK2(MAP2K2). The...
phosphorylation of extracellular regulatory kinase 1 (ERK-1, also known as MAPK3), which sustains cell survival over time, and inhibition of stress-activated...
spontaneous 1.52 megabase inversion that disrupts the gene in an affected child. MAPK3 16p11.2 A 2008 study observed a de novo deletion of 593 kb on this chromosome...