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Lactose information


Lactose
Names
IUPAC name
β-D-Galactopyranosyl-(1→4)-D-glucose
Systematic IUPAC name
(2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-{[(2R,3S,4R,5R,6R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy}oxane-3,4,5-triol
Other names
Milk sugar
Lactobiose
4-O-β-D-Galactopyranosyl-D-glucose
Identifiers
CAS Number
  • 63-42-3 checkY
3D model (JSmol)
  • Interactive image
Beilstein Reference
90841
ChEBI
  • CHEBI:36218 checkY
ChEMBL
  • ChEMBL417016 checkY
ChemSpider
  • 5904 checkY
ECHA InfoCard 100.000.509 Edit this at Wikidata
EC Number
  • 200-559-2
Gmelin Reference
342369
KEGG
  • C01970
PubChem CID
  • 6134
UNII
  • 3SY5LH9PMK checkY
CompTox Dashboard (EPA)
  • DTXSID2023193 Edit this at Wikidata
InChI
  • InChI=1S/C12H22O11/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17/h3-20H,1-2H2/t3-,4-,5+,6+,7-,8-,9-,10-,11-,12+/m1/s1 checkY
    Key: GUBGYTABKSRVRQ-DCSYEGIMSA-N checkY
  • InChI=1/C12H22O11/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17/h3-20H,1-2H2/t3-,4-,5+,6+,7-,8-,9-,10-,11-,12+/m1/s1
    Key: GUBGYTABKSRVRQ-DCSYEGIMBP
SMILES
  • C([C@@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2O)O)O)CO)O)O)O)O
Properties
Chemical formula
C12H22O11
Molar mass 342.297 g·mol−1
Appearance White solid
Density 1.525 g/cm3
Melting point 252 °C (anhydrous)[1]
202 °C (monohydrate)[1]
Solubility in water
195 g/L[2][3]
Chiral rotation ([α]D)
+55.4° (anhydrous)
+52.3° (monohydrate)
Thermochemistry
Std enthalpy of
combustion cH298)
5652 kJ/mol, 1351 kcal/mol, 16.5 kJ/g, 3.94 kcal/g
Hazards
NFPA 704 (fire diamond)
NFPA 704 four-colored diamondHealth 0: Exposure under fire conditions would offer no hazard beyond that of ordinary combustible material. E.g. sodium chlorideFlammability 0: Will not burn. E.g. waterInstability 0: Normally stable, even under fire exposure conditions, and is not reactive with water. E.g. liquid nitrogenSpecial hazards (white): no code
0
0
0
Flash point 357.8 °C (676.0 °F; 631.0 K)[4]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)
Infobox references

Lactose, or milk sugar, is a disaccharide sugar composed of galactose and glucose subunits and has the molecular formula C12H22O11. Lactose makes up around 2–8% of milk (by mass). The name comes from lact (gen. lactis), the Latin word for milk, plus the suffix -ose used to name sugars. The compound is a white, water-soluble, non-hygroscopic solid with a mildly sweet taste. It is used in the food industry.[5]

  1. ^ a b Peter M. Collins (2006). Dictionary of Carbohydrates (2nd ed.). Boca Raton: Chapman & Hall/CRC. p. 677. ISBN 978-0-8493-3829-8.
  2. ^ "D-Lactose".
  3. ^ The solubility of lactose in water is 189.049 g at 25 °C, 251.484 g at 40 °C and 372.149 g at 60 °C per kg solution. Its solubility in ethanol is 0.111 g at 40 °C and 0.270 g at 60 °C per kg solution.Machado, José J. B.; Coutinho, João A.; Macedo, Eugénia A. (2001), "Solid–liquid equilibrium of α-lactose in ethanol/water" (PDF), Fluid Phase Equilibria, 173 (1): 121–34, doi:10.1016/S0378-3812(00)00388-5. ds
  4. ^ Sigma Aldrich
  5. ^ Gerrit M. Westhoff; Ben F.M. Kuster; Michiel C. Heslinga; Hendrik Pluim; Marinus Verhage (2014). "Lactose and Derivatives". Ullmann's Encyclopedia of Industrial Chemistry. Wiley-VCH. pp. 1–9. doi:10.1002/14356007.a15_107.pub2. ISBN 978-3-527-30673-2.

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Lactose

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Lactose, or milk sugar, is a disaccharide sugar composed of galactose and glucose subunits and has the molecular formula C12H22O11. Lactose makes up around...

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Lactose intolerance

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Lactose intolerance is caused by a lessened ability or a complete inability to digest lactose, a sugar found in dairy products. Humans vary in the amount...

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Lac operon

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The lactose operon (lac operon) is an operon required for the transport and metabolism of lactose in E. coli and many other enteric bacteria. Although...

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Lactase

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the lactose naturally found in milk, leaving it slightly sweet but digestible by everyone. Without lactase, lactose intolerant people pass the lactose undigested...

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February

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February is the second month of the year in the Julian and Gregorian calendars. The month has 28 days in common years or 29 in leap years, with the 29th...

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Kefir

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lactose down into glucose and galactose. As a result of the fermentation, lactose levels are decreased by 20–30% with respect to the initial lactose levels...

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Lactase persistence

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activity of the lactase enzyme in adulthood, allowing the digestion of lactose in milk. In most mammals, the activity of the enzyme is dramatically reduced...

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Lactose permease

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Lactose permease is a membrane protein which is a member of the major facilitator superfamily. Lactose permease can be classified as a symporter, which...

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Dairy product

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varying degrees. Some people avoid some or all dairy products because of lactose intolerance, veganism, environmental concerns, other health reasons or...

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MacConkey agar

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intestinal tract) bacteria and differentiate them based on lactose fermentation. Lactose fermenters turn red or pink on MacConkey agar, and nonfermenters...

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FODMAP

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and galactooligosaccharides (GOS, stachyose, raffinose), disaccharides (lactose), monosaccharides (fructose), and sugar alcohols (polyols), such as sorbitol...

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Milk

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Milk contains many nutrients, including calcium and protein, but also lactose and saturated fat. As an agricultural product, dairy milk is collected...

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Yogurt

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people with lactose malabsorption. Lactose intolerance is a condition in which people have symptoms due to the decreased ability to digest lactose, a sugar...

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Galactose

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of glucose. A galactose molecule linked with a glucose molecule forms a lactose molecule. Galactan is a polymeric form of galactose found in hemicellulose...

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Lac repressor

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coding for proteins involved in the metabolism of lactose in bacteria. These genes are repressed when lactose is not available to the cell, ensuring that the...

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Lactic acid fermentation

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six-carbon sugars (also, disaccharides of six-carbon sugars, e.g. sucrose or lactose) are converted into cellular energy and the metabolite lactate, which is...

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Lactose synthase

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Lactose synthase is an enzyme that generates lactose from glucose and UDP-galactose. It is classified under EC 2.4.1.22. It consists of N-acetyllactosamine...

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Milk substitute

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particularly important to consumers who suffer from cow's milk allergies, lactose intolerances or hypercholesterolemia. Individuals who adhere to dairy-free...

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Whey cheese

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cheeses, about 50% of milk solids remain in the whey, including most of the lactose and lactalbumin. The production of whey cheese allows cheesemakers to use...

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Eosin methylene blue

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bacteria that ferment lactose (e.g., E. coli) from those that do not (e.g., Salmonella, Shigella). Organisms that ferment lactose appear dark/black or...

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Carbohydrate

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sugars, e.g. fructose (fruit sugar), sucrose (cane or beet sugar), ribose, lactose (milk sugar), etc. Carbohydrates perform numerous roles in living organisms...

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Whey

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while sour whey contains about 0.1% fat. The carbohydrates are mainly lactose. The proteins are known as lactalbumin. Whey also contains some minerals...

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HYLA

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('hydrolysed lactose') and refers to the low lactose content of HYLA milk products. Milk products with the HYLA label contain less than 1% lactose, so they...

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Disaccharide

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are simple sugars soluble in water. Three common examples are sucrose, lactose, and maltose. Disaccharides are one of the four chemical groupings of carbohydrates...

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Coliform bacteria

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based on lactose fermentation abilities. Strong lactose fermenters will appear as dark blue/purple/black, and E.coli (which also ferments lactose) colonies...

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Forsythia

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forsythia flowers produce lactose, but lactose occurs only very rarely in natural sources other than milk, and attempts to find lactose in forsythia have been...

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Allolactose

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lactose. It consists of the monosaccharides D-galactose and D-glucose linked through a β1-6 glycosidic linkage instead of the β1-4 linkage of lactose...

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