Lactase (EC 3.2.1.108) is an enzyme produced by many organisms and is essential to the complete digestion of whole milk. It breaks down the sugar lactose into its component parts, galactose and glucose. Lactase is found in the brush border of the small intestine of humans and other mammals. People deficient in lactase or lacking functional lactase may experience the symptoms of lactose intolerance after consuming milk products.[1] Microbial β-galactosidase (often loosely referred to as lactase) can be purchased as a food supplement and is added to milk to produce "lactose-free" milk products.
^Järvelä I, Torniainen S, Kolho KL (2009). "Molecular genetics of human lactase deficiencies". Annals of Medicine. 41 (8): 568–75. doi:10.1080/07853890903121033. PMID 19639477. S2CID 205586720.
Lactase (EC 3.2.1.108) is an enzyme produced by many organisms and is essential to the complete digestion of whole milk. It breaks down the sugar lactose...
extremely rare genetic disorder in which little or no lactase is made from birth. The reduction of lactase production starts typically in late childhood or...
Lactase persistence or lactose tolerance is the continued activity of the lactase enzyme in adulthood, allowing the digestion of lactose in milk. In most...
lactase production into adulthood due to dietary consumption of milk products throughout adulthood driving selection for genes that continue lactase production...
with the promoter, and express the genes, which synthesize lactase. Eventually, the lactase will digest all of the lactose, until there is none to bind...
with the promoter, and express the genes, which synthesize lactase. Eventually, the lactase will digest all of the lactose, until there is none to bind...
oligosaccharides. Other brush border enzymes are maltase, sucrase and lactase. Lactase is absent in some adult humans and, for them, lactose (a disaccharide)...
so-called invert sugar. Lactase is essential for digestive hydrolysis of lactose in milk; many adult humans do not produce lactase and cannot digest the...
with the promoter, and express the genes, which synthesize lactase. Eventually, the lactase will digest all of the lactose, until there is none to bind...
"Herders of Indian and European Cattle Share their Predominant Allele for Lactase Persistence". Mol. Biol. Evol. 29 (1): 249–260. doi:10.1093/molbev/msr190...
"Gene-culture coevolution between cattle milk protein genes and human lactase genes". Nature Genetics. 35 (4): 311–313. doi:10.1038/ng1263. PMID 14634648...
Zhang J, Fan R (February 2015). "Association of lymphocytic colitis and lactase deficiency in pediatric population". Pathology, Research and Practice....
out: the suffix -ase is combined with the name of the substrate (e.g., lactase is the enzyme that cleaves lactose) or to the type of reaction (e.g., DNA...
ability to digest milk was limited to children as adults did not produce lactase, an enzyme necessary for digesting the lactose in milk. People therefore...
PMID 20089146. Ségurel, Laure; Bon, Céline (31 August 2017). "On the Evolution of Lactase Persistence in Humans". Annual Review of Genomics and Human Genetics. 18...
Sudan, where lactase persistence evolved independently. The uniformity of the mutations surrounding the lactase gene suggests that lactase persistence...
patients with rare hereditary problems of galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption Fluconazole is an inhibitor...
kombu. Additionally, for individuals with lactose intolerance, taking a lactase-containing product with lactose-containing foodstuffs may reduce flatulence...
abnormality involves a single step in the absorptive process, as in primary lactase deficiency, or if the disease process is limited to the very proximal small...
reducing the volume and frequency of flatus. The enzymes alpha-galactosidase, lactase, amylase, lipase, protease, cellulase, glucoamylase, invertase, malt diastase...
Lactose in food (such as dairy products) is broken down by the enzyme lactase into glucose and galactose. In individuals with galactosemia, the enzymes...
be present due to the decreased bowel surface and reduced production of lactase but typically resolves once the condition is treated.[citation needed]...
Single-Nucleotide Polymorphism 13.9 kb Upstream of the Lactase Gene (LCT) (C−13.9kbT) Does Not Predict or Cause the Lactase-Persistence Phenotype in Africans". The American...
including East Asian types of ADH1B associated with rice domestication, or lactase persistence, are due to recent selection pressures. An even more recent...
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