Kluyveromyces lactis is a Kluyveromyces yeast commonly used for genetic studies and industrial applications. Its name comes from the ability to assimilate lactose and convert it into lactic acid.
Kluyveromyces lactis (formerly Saccharomyces lactis) is a yeast which has the ability to assimilate lactose and convert it into lactic acid. K. lactis and other organisms i.e., Aspergillus niger var awamori and Escherichia coli K-12 are grown in fermenters to produce chymosin (rennet) on a commercial scale; this rennet, which replaces the conventional form obtained from slaughtered animals, is now widely used in cheese production.
Yeasts and fungi are ideal organisms for comparative genomic studies in eukaryotes because of their small and compact genomes and because they include a number of species such as Neurospora crassa, Saccharomyces cerevisiae and Schizosaccharomyces pombe, that have been, and continue to be, used extensively in genetic studies. However, the divergence between these three species is ancient (estimated to be at least 300 million years old) and the organization of their genomes is quite different. The diversity of the hemiascomycetes, a group of ascomycetes that contains most of the known yeast species, was first explored in 2000.
Complete sequencing and comparison of four hemiascomycetous yeasts has been undertaken for Candida glabrata, Kluyveromyces lactis, Debaryomyces hansenii, and Yarrowia lipolytica. They were selected on the basis of their phylogenetic positions and their specific interest as human pathogens, or as industrially or environmentally important yeasts. This work, which represents the first multispecies exploration of genome evolution across an entire eukaryotic phylum, reveals the variety of events and mechanisms that have taken place, and should allow useful comparisons with other phyla of multicellular organisms when more genome sequences are determined.
K. lactis is a heterothallic species with a predominantly haplontic cycle, in contrast to S. cerevisiae in which the predominantly diplobiontic cycle is pseudo-heterothallic due to mating-type switching.[1]
assimilate lactose and convert it into lactic acid. Kluyveromyceslactis (formerly Saccharomyces lactis) is a yeast which has the ability to assimilate lactose...
mutants. Kluyveromyces is widely cultured for microbiological en genetic research. Some important species include: KluyveromyceslactisKluyveromyces marxianus...
Kluyveromyces marxianus in ascomycetous yeast and member of the genus, Kluyveromyces. It is the sexual stage of Atelosaccharomyces pseudotropicalis [citation...
the K28 toxin by forming a complex with it. Killer properties of Kluyveromyceslactis are associated with linear DNA plasmids, which have on their 5'end...
strains of yeast that can metabolize lactose, such as Kluyveromyces marxianus, Kluyveromyceslactis, and Saccharomyces fragilis, as well as strains of yeast...
Debaryomyces hansenii and its non-sporulating form Candida famata, and Kluyveromyceslactis and its non-sporulating form Candida sphaerica. Similarly to other...
oxygen. If oxygen is present, some species of yeast (e.g., Kluyveromyceslactis or Kluyveromyces lipolytica) will oxidize pyruvate completely to carbon dioxide...
commercially can be extracted both from yeasts such as Kluyveromyces fragilis and Kluyveromyceslactis and from molds, such as Aspergillus niger and Aspergillus...
recombinantly in Escherichia coli, Aspergillus niger var. awamori, and Kluyveromyceslactis.[citation needed] Chymosin is found in a wide range of tetrapods...
trademark CHY-MAX by the Danish company Chr. Hansen, or produced by Kluyveromyceslactis and commercialized under the trademark Maxiren by the Dutch company...
"Undd Bertholetus praeparat ex sero lactis remedium, quod vocat mannam S. [alchemical symbol for salt, salem] seri lactis vid. in Encyclopaed. p. 400. Praeparatio...
substrates; it is thermo-tolerant and can assimilate nitrate (see also Kluyveromyceslactis). It has been applied to the production of hepatitis B vaccines,...
used for genetic engineering of yeast—and linear pGKL plasmids from Kluyveromyceslactis, that are responsible for killer phenotypes. Other types of plasmids...
produced in yeast. Another yeast used for protein production is Kluyveromyceslactis and the gene is expressed, driven by a variant of the strong lactase...
2012). "Functional analysis of the single Est1/Ebs1 homologue in Kluyveromyceslactis reveals roles in both telomere maintenance and rapamycin resistance"...
despite its small, compact genome (~13Mbp), after the divergence from Kluyveromyceslactis and K. marxianus. Through genome streamlining, yeast has lost 90%...
which includes chitinase, chitodextrinase and the killer toxin of Kluyveromyceslactis. The chitinases hydrolyse chitin oligosaccharides. Another chitinase...
Araecerus fasciculatus, to Volatiles from the Industrial Yeast Kluyveromyceslactis". Journal of Chemical Ecology. 43 (2): 180–187. Bibcode:2017JCEco...
on the catalytic activity of the immobilized β-galactosidase from Kluyveromyceslactis". Biochemical Engineering Journal. 9 (1): 33–40. doi:10.1016/s1369-703x(01)00118-8...
studying other yeasts of biotechnological or medical interest, such as Kluyveromyceslactis and Candida glabrata. In Gif-sur-Yvette, Bernard Dujon started to...
There are homologues of AnPRT within Saccharomyces cerevisiae, Kluyveromyceslactis, Schizosaccharomyces pombe, Magnaporthe grisea, Neurospora crassa...
Genetically modified producers were developed such as Kluysveromyces lactis, Lactococcus lactis, Bacillus subtilis, Escherichia coli, and Corynebacterium...
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