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Isoquinoline alkaloids information


Isoquinoline, the parent compound of the isoquinoline alkaloids

Isoquinoline alkaloids are natural products of the group of alkaloids, which are chemically derived from isoquinoline. They form the largest group among the alkaloids.[1]

Isoquinoline alkaloids can be further classified based on their different chemical basic structures. The most common structural types are the benzylisoquinolines and the aporphines.[2] According to current knowledge, a total of about 2500 isoquinoline alkaloids are known nowadays, which are mainly formed by plants.[3]

  1. ^ Gerhard Habermahl, Peter E. Hammann, Hans C. Krebs, Waldemar Ternes: Naturstoffe. Springer-Verlag, Berlin/ Heidelberg 2008, ISBN 978-3-540-73733-9, doi:10.1007/978-3-540-73733-9, S. 176–187.
  2. ^ Bettina Ruff: Chemische und biochemische Methoden zur stereoselektiven Synthese von komplexen Naturstoffen. Verlag Logos, Berlin 2012, ISBN 978-3-8325-3121-8, S. 8. ([1], p. 8, at Google Books)
  3. ^ Jennifer M. Finefield, David H. Sherman, Martin Kreitman, Robert M. Williams: Enantiomere Naturstoffe: Vorkommen und Biogenese. In: Angewandte Chemie. Wiley-VCH, Weinheim 2012, doi:10.1002/ange.201107204, S. 4905–4915.

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Isoquinoline alkaloids

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Isoquinoline alkaloids are natural products of the group of alkaloids, which are chemically derived from isoquinoline. They form the largest group among...

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Isoquinoline

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natural plant alkaloids, any one of which might be referred to as "an isoquinoline". It is a structural isomer of quinoline. Isoquinoline and quinoline...

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Alkaloid

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compounds of similar structure may also be termed alkaloids. In addition to carbon, hydrogen and nitrogen, alkaloids may also contain oxygen or sulfur. More rarely...

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Benzylisoquinoline alkaloids

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benzylisoquinoline. They also include the benzyl(tetrahydro)isoquinoline alkaloids. Benzylisoquinoline alkaloids are found in several plant families, including the...

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Aporphine alkaloids

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alkaloids they are the second largest group of isoquinoline alkaloids. At least 85 aporphine alkaloids have been isolated from plants of 15 families....

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Sanguinaria

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Sanguinaria root is rich in isoquinoline alkaloids, mainly sanguinarine and chelerythrine. Sanguinarine is a benzophenanthridine alkaloid (see phenanthridine)...

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Lamprocapnos

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cause skin irritation in certain individuals, due to its containing isoquinoline alkaloids, including protopine, while consumption of the leaves can give rise...

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Chelidonium majus

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doses as it contains a range of isoquinoline alkaloids; use in herbal medicine requires the correct dose. The main alkaloid present in the herb and root...

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Goldenseal

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Goldenseal in flower Goldenseal in fruit Goldenseal contains the isoquinoline alkaloids hydrastine, berberine, berberastine, hydrastinine, tetrahydroberberastine...

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Jateorhiza palmata

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(calumba) is a perennial climbing plant from East Africa. It contains isoquinoline alkaloids and is used mainly as a bitter tonic especially in cases of anorexia...

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Narcotic

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specific chemical designation. Such a term does not include the isoquinoline alkaloids of opium. (ii) Poppy straw and concentrate of poppy straw. (iii)...

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Corydalis Alkaloids

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Corydalis Alkaloids are categorized as natural products of the isoquinoline alkaloid type. Corydalis alkaloids are primarily located within the roots of...

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Argemone mexicana

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katkar oil, which contains the toxic alkaloids sanguinarine and dihydrosanguinarine. Four quaternary isoquinoline alkaloids, dehydrocorydalmine, jatrorrhizine...

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Chelidonine

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Papaveraceae. Papaveraceae is rich in specific alkaloids. C. majus contains various isoquinoline alkaloids with protopine, protoberberine and benzophenanthridine...

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Bisbenzylisoquinoline alkaloids

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alkaloids are known and have been isolated. The bisbenzylisoquinoline alkaloids are considered the largest group within the isoquinoline alkaloids. The...

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Reserpine

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reserpine's effects are long-lasting. Reserpine is one of dozens of indole alkaloids isolated from the plant Rauvolfia serpentina. In the Rauvolfia plant,...

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Sanguinarine

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to that of sanguinarine. Chelidonine Santos AC, Adkilen P (1932). "The Alkaloids of Argemone Mexicana". Journal of the American Chemical Society. 54 (7):...

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Synthon

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been used extensively for the synthesis of numerous indole and isoquinoline alkaloids. Carbanion alkylation is a common strategy used to create carbon-carbon...

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Hippeastrum

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least 64 isoquinoline alkaloids, which include anti-parasitic (e.g. candimine) and psychopharmacological activity due to their high alkaloid content....

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Lycorine

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Regenthal, Ralf; Karst, Uwe (2012). "Metabolic studies of the Amaryllidaceous alkaloids galantamine and lycorine based on electrochemical simulation in addition...

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Fumaria officinalis

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effect on pregnant woman, children or elderly. The plant contains isoquinoline alkaloids protopine and allocryptopine. Both protopine and allocryptopine...

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Dehydrocorybulbine

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ZZ; Xu, W; Jensen, NH; Roth, BL; Liu-Chen, LY; Lee, DY (2008). "Isoquinoline alkaloids isolated from Corydalis yanhusuo and their binding affinities at...

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Dihydrosanguinarine

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Dihydrosanguinarine 10-monooxygenase Epidemic dropsy Sanguinarine Israilov I, Melikov F, Murav'eva D. Alkaloids of Dicentra. Chem Nat Compd 1984; 20:74–76. v t e v t e...

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Virstatin

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testing of one of the hits in infected mice. The compound is an isoquinoline alkaloid and can be synthesized by a simple two-step synthesis Anthouard...

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Benzylisoquinoline

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Substitution of the heterocycle isoquinoline at the C1 position by a benzyl group provides 1‑benzylisoquinoline, the most widely examined of the numerous...

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Erysodienone

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Erythrina-produced alkaloids. Early work was done by Derek Barton and co-workers to illustrate the biosynthetic pathways towards erythrina alkaloids. It was demonstrated...

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List of poisonous plants

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Singh, T. D.; Singh, V. P.; Pandey, V. B. (February 2010). "Quaternary Alkaloids of Argemone mexicana". Pharmaceutical Biology. 48 (2): 158–160. doi:10...

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Tetrahydropalmatine

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Tetrahydropalmatine (THP) is an isoquinoline alkaloid found in several different plant species, mainly in the genus Corydalis (Yan Hu Suo), but also in...

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Corydalis mucronifera

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previously undiscovered and were named mucroniferanines H-M. Alkaloids, specifically isoquinoline alkaloids, are part of an extensive family of phytochemicals,...

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