Testing of living muscle tissue outside of an organism
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In vitro muscle testing is a method used to characterize properties of living muscle tissue after removing it from an organism, which allows more extensive and precise quantification of its properties than in vivo testing. In vitro muscle testing has provided the bulk of scientific knowledge of muscle structure and physiology, and how both relate to organismal performance. Stem cell research relies on in vitro muscle testing to establish sole muscle cell function and its individual behavior apart from muscle cells in the presence of nonmuscle cells seen in in vitro studies.[1]
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used inmuscle physiology to evaluate the mechanical work and power output of skeletal or cardiac muscle contractions via invitromuscletesting of whole...
idea. Invitro cultivation of muscle fibers was first performed successfully in 1971 when pathologist Russel Ross cultured guinea-pig aorta. In 1991,...
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Cardiac muscle (also called heart muscle or myocardium) is one of three types of vertebrate muscle tissues, with the other two being skeletal muscle and smooth...
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Internet and identification of invitro generated phase-I metabolites for human sports drug testing". Rapid Communications in Mass Spectrometry. 29 (11):...
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that in humans is encoded by the MSTN gene. Myostatin is a myokine that is produced and released by myocytes and acts on muscle cells to inhibit muscle growth...
neuromuscular disorder that results in the loss of motor neurons and progressive muscle wasting. It is usually diagnosed in infancy or early childhood and...
known as satellite cells, muscle stem cells or MuSCs, are small multipotent cells with very little cytoplasm found in mature muscle. Satellite cells are precursors...
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suppressor of DUX4 invitro. Results of a phase IIb clinical trial, revealed in June 2021, showed statistically significant slowing of muscle function deterioration...
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electromyographic (EMG) testing called the long exercise test. This test measures the amplitude of a nerve response (called the Compound Muscle Action Potential...
caused by imbalances in the actions of muscles that rotate the eyes. This condition can sometimes be relieved by weakening a muscle that pulls too strongly...
abdominal muscles. Abductor pollicis brevis muscle – A musclein the hand that abducts (straightens) the thumb. Abductor pollicis longus muscle – One of...
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dehydrogenase (cytochrome). LDH is expressed extensively in body tissues, such as blood cells and heart muscle. Because it is released during tissue damage, it...
Spain who also practiced dissection, introduced animal testing as an experimental method of testing surgical procedures before applying them to human patients...
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