ImmunoGen, Inc. was a biotechnology company focused on the development of antibody-drug conjugate (ADC) therapeutics for the treatment of cancer. ImmunoGen was founded in 1981 and was headquartered in Waltham, Massachusetts.[2]
An ImmunoGen ADC contains a manufactured antibody that binds to a target found on cancer cells, with one of the company's potent cell-killing agents attached as a "payload". The antibody serves to deliver the cell-killing agent specifically to cancer cells bearing its target and the payload serves to kill these cells. In some cases, the antibody also has anticancer activity.
In November 2023, AbbVie, an American pharmaceutical company, announced it was buying ImmunoGen for 10.1 billion.[3][4]
ImmunoGen, Inc. was a biotechnology company focused on the development of antibody-drug conjugate (ADC) therapeutics for the treatment of cancer. ImmunoGen...
An immunogen is any substance that generates B-cell (humoral/antibody) and/or T-cell (cellular) adaptive immune responses upon exposure to a host organism...
would be buying ImmunoGen for $10.1 billion, aiming to expedite its entry into the ovarian cancer treatment market with ImmunoGen's drug Elahere. The...
according to the WHO. DM1 and its attachment via these linkers result from ImmunoGen Inc research. An example is: Trastuzumab emtansine (T-DM1), an anti-HER2/neu...
Biotechnology News. ImmunoGen reports encouraging clinical data of IMGN901. News-medical.net. Retrieved on 2010-11-20. "ImmunoGen receives FDA orphan...
(huC242) linked to a cytotoxic agent, mertansine (DM1). It was developed by ImmunoGen. After the huC242 mab binds to the external domain of CanAg, the cantuzumab...
Addgene Biogen Boston Scientific Conagen Foundation Medicine GSK Genzyme ImmunoGen Intarcia Therapeutics Moderna Therapeutics NovoBiotic Pharmaceuticals...
Isatuximab is the United States Adopted Name (USAN). It was developed by ImmunoGen and Sanofi-Aventis with the development name SAR-650984.[citation needed]...
response, it is an 'immunogenic antigen', which is referred to as an immunogen. Many lipids and nucleic acids are relatively small molecules and/or have...
immune system becomes fortified against an infectious agent (known as the immunogen). When this system is exposed to molecules that are foreign to the body...
molecular form. If its molecular form is changed, a tolerogen can become an immunogen. Immunoglobulin-binding protein – Proteins such as protein A, protein...
(docetaxel or paclitaxel). On 22 October 2015, Roche and co-developer ImmunoGen disclosed that trastuzumab emtansine had failed to meet its primary endpoint...
interest) are sometimes constructed to express more than one immunogen, or to express an immunogen and an immunostimulatory protein. Because the plasmid –...
Ansamitocin Mertansine / emtansine (DM1) Ravtansine / soravtansine (DM4) ImmunoGen, developer of maytansinoid based drugs National Cancer Institute: Definition...
Androvax, also known as androstenedione:human serum albumin conjugate, is an immunogen and vaccine against androstenedione that is used in veterinary medicine...
institute also incorporates the: Center for HIV/AIDS Vaccine Immunology & Immunogen Discovery Center for Metabolomics Center for Viral Systems Biology[citation...
(2018-03-08). "Common Features of Enveloped Viruses and Implications for Immunogen Design for Next-Generation Vaccines". Cell. 172 (6): 1319–1334. doi:10...
she co-discovered the vault (organelle). Subsequently, she worked at ImmunoGen Inc. where she worked on staining and photographing different cancer cells...
Vaccine Institute and the Duke Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery (CHAVI-ID), which was funded by the National Institute of Allergy...
based on an antibody layer that interacts selectively with a particular immunogen and reports about its content in a specimen. In the static mode of operation...
and preservatives) very little of which is the active ingredient, the immunogen. A single dose may have merely nanograms of virus particles, or micrograms...
(Fecundin), a conjugate of androstenedione and human serum albumin and an immunogen and vaccine against androstenedione that is used to generate androgen...
investments of the 1970s were Biogen, Artificial Intelligence Software, Immunogen and Digital Research. Jacqui Morby, one of the first women to become a...
Approach. Medicus Media. p. 2371. ISBN 0803613245. "Antibody Production (Immunogen Preparation)". www.piercenet.com. Archived from the original on 2013-10-17...
Global Information
$65.2 million (2019)[1]