IRF7 information

IRF7
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2O61
Identifiers
Aliases	IRF7, IRF-7H, IRF7A, IRF7B, IRF7C, IRF7H, IMD39, interferon regulatory factor 7, IRF-7
External IDs	OMIM: 605047 MGI: 1859212 HomoloGene: 128624 GeneCards: IRF7
Gene location (Human)
Chr.	Chromosome 11 (human)
End	615,983 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	140,846,394 bp
RNA expression pattern
	Top expressed in
	blood; ; right lobe of liver; ; spleen; ; monocyte; ; lymph node; ; bone marrow; ; bone marrow cells; ; sural nerve; ; appendix; ; left lobe of thyroid gland;
	Top expressed in
	blood; ; mucous cell of stomach; ; ileum; ; jejunum; ; duodenum; ; large intestine; ; colon; ; thymus; ; spleen; ; submandibular gland;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; DNA-binding transcription factor activity; protein binding; RNA polymerase II core promoter sequence-specific DNA binding; transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding; cis-regulatory region sequence-specific DNA binding;
Cellular component	nucleoplasm; endosome membrane; nucleus; cytoplasm; cytosol;
Biological process	positive regulation of type I interferon-mediated signaling pathway; regulation of transcription, DNA-templated; positive regulation of interferon-alpha production; MDA-5 signaling pathway; interferon-gamma-mediated signaling pathway; immune system process; regulation of adaptive immune response; response to virus; negative regulation of transcription by RNA polymerase II; transcription by RNA polymerase II; transcription, DNA-templated; regulation of type I interferon production; cellular response to DNA damage stimulus; TRIF-dependent toll-like receptor signaling pathway; positive regulation of transcription, DNA-templated; negative regulation of macrophage apoptotic process; type I interferon signaling pathway; immunoglobulin mediated immune response; establishment of viral latency; regulation of immune response; viral process; regulation of monocyte differentiation; positive regulation of transcription by RNA polymerase II; positive regulation of interferon-beta production; interferon-beta production; regulation of MyD88-independent toll-like receptor signaling pathway; positive regulation of type I interferon production; innate immune response; regulation of MyD88-dependent toll-like receptor signaling pathway; interferon-alpha production; defense response to virus; regulation of gene expression;
	Sources:Amigo / QuickGO
Orthologs
	3665
	54123
	ENSG00000276561; ENSG00000185507
	ENSMUSG00000025498
	Q92985
	P70434
	NM_001572; NM_004029; NM_004030; NM_004031
	NM_001252600; NM_001252601; NM_016850
	NP_001563; NP_004020; NP_004022
	NP_001239529; NP_001239530; NP_058546
	Wikidata
View/Edit Human	View/Edit Mouse

Interferon regulatory factor 7, also known as IRF7, is a member of the interferon regulatory factor family of transcription factors.

^ ^a ^b ^c ENSG00000185507 GRCh38: Ensembl release 89: ENSG00000276561, ENSG00000185507 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000025498 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[refGRCh38Ensembl-1] ENSG00000185507 GRCh38: Ensembl release 89: ENSG00000276561, ENSG00000185507 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000025498 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

IRF7 information

and 19 Related for: IRF7 information

IRF7

Iridium

Interferon type I

Iridium tetroxide

Rotavirus

List of human transcription factors

Iridium compounds

Aryl hydrocarbon receptor

List of distinct cell types in the adult human body

Osmiridium

Chikungunya

Innate immune system

IRF3

David Baltimore

MDA5

Iridium trifluoride

Iridium tetrabromide

FADD

HHV Infected Cell Polypeptide 0