IRF5 information

IRF5
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3DSH
Identifiers
Aliases	IRF5, SLEB10, interferon regulatory factor 5
External IDs	OMIM: 607218; MGI: 1350924; HomoloGene: 8088; GeneCards: IRF5; OMA:IRF5 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	128,950,038 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	29,541,870 bp
RNA expression pattern
	Top expressed in
	monocyte; ; granulocyte; ; spleen; ; blood; ; bone marrow cells; ; lymph node; ; upper lobe of left lung; ; testicle; ; right uterine tube; ; right coronary artery;
	Top expressed in
	mesenteric lymph nodes; ; stroma of bone marrow; ; granulocyte; ; spleen; ; lip; ; right kidney; ; female urethra; ; proximal tubule; ; esophagus; ; blastocyst;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA binding; DNA-binding transcription factor activity; protein binding; DNA-binding transcription activator activity, RNA polymerase II-specific; sequence-specific DNA binding; identical protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	cytoplasm; cytosol; nucleus;
Biological process	regulation of transcription, DNA-templated; positive regulation of interleukin-12 production; interferon-gamma-mediated signaling pathway; immune system process; regulation of transcription by RNA polymerase II; positive regulation of interferon-alpha production; response to muramyl dipeptide; transcription, DNA-templated; defense response to virus; type I interferon signaling pathway; response to peptidoglycan; positive regulation of apoptotic process; innate immune response; positive regulation of transcription by RNA polymerase II; positive regulation of interferon-beta production; cytokine-mediated signaling pathway; transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	3663
	27056
	ENSG00000128604
	ENSMUSG00000029771
	Q13568
	P56477
NM_001098627; NM_001098629; NM_001098630; NM_001242452; NM_032643;
	NM_001347928; NM_001364314
	NM_001252382; NM_012057; NM_001311083
NP_001092097; NP_001092099; NP_001092100; NP_001229381; NP_116032;
	NP_001334857; NP_001351243; NP_001092099.1
	NP_001239311; NP_001298012; NP_036187
	Wikidata
View/Edit Human	View/Edit Mouse

Interferon regulatory factor 5 is a protein that in humans is encoded by the IRF5 gene.^[5] The IRF family is a group of transcription factors that are involved in signaling for virus responses in mammals along with regulation of certain cellular functions.^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000128604 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000029771 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: IRF5 interferon regulatory factor 5".
^ Negishi H, Taniguchi T, Yanai H (2018-11-01). "The Interferon (IFN) Class of Cytokines and the IFN Regulatory Factor (IRF) Transcription Factor Family". Cold Spring Harbor Perspectives in Biology. 10 (11): a028423. doi:10.1101/cshperspect.a028423. ISSN 1943-0264. PMC 6211389. PMID 28963109.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000128604 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000029771 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: IRF5 interferon regulatory factor 5".

[:0-6] Negishi H, Taniguchi T, Yanai H (2018-11-01). "The Interferon (IFN) Class of Cytokines and the IFN Regulatory Factor (IRF) Transcription Factor Family". Cold Spring Harbor Perspectives in Biology. 10 (11): a028423. doi:10.1101/cshperspect.a028423. ISSN 1943-0264. PMC 6211389. PMID 28963109.

IRF5 information

and 28 Related for: IRF5 information

IRF5

Iridium

Iridium tetrafluoride

Sarin

Iridium fluoride

List of CAS numbers by chemical compound

Potassium fluoride

Pentafluoride

Boron trifluoride etherate

Trichlorofluoromethane

List of human transcription factors

Lupus

Hydrogen fluoride

Nitrogen trifluoride

Sodium fluoride

Bromotrifluoromethane

Fluoroantimonic acid

Fluorocarbon

Dichlorodifluoromethane

Interferon regulatory factors

Dioxygen difluoride

Oxygen fluoride

Halogen

Plutonium pentafluoride

Lithium hexafluorotitanate

Krypton hexafluoride

Hexaoxygen difluoride

Lithium fluoride