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Sodium fluoride information


Sodium fluoride
Sodium fluoride
Sample of sodium fluoride, AR grade
Names
Pronunciation /ˌsdiəm ˈflʊərd/[1]
IUPAC name
Sodium fluoride
Other names
Florocid
Identifiers
CAS Number
  • 7681-49-4 checkY
ChEBI
  • CHEBI:28741 checkY
ChEMBL
  • ChEMBL1528 checkY
ChemSpider
  • 5045 checkY
ECHA InfoCard 100.028.789 Edit this at Wikidata
EC Number
  • 231-667-8
KEGG
  • C08142 ☒N
PubChem CID
  • 5235
RTECS number
  • WB0350000
UNII
  • 8ZYQ1474W7 checkY
UN number 1690
CompTox Dashboard (EPA)
  • DTXSID2020630 Edit this at Wikidata
InChI
  • InChI=1S/FH.Na/h1H;/q;+1/p-1 checkY
    Key: PUZPDOWCWNUUKD-UHFFFAOYSA-M checkY
  • InChI=1/FH.Na/h1H;/q;+1/p-1
    Key: PUZPDOWCWNUUKD-REWHXWOFAH
Properties
Chemical formula
NaF
Molar mass 41.988173 g/mol
Appearance White to greenish solid
Odor odorless
Density 2.558 g/cm3
Melting point 993 °C (1,819 °F; 1,266 K)
Boiling point 1,704 °C (3,099 °F; 1,977 K)
Solubility in water
36.4 g/L (0 °C);
40.4 g/L (20 °C);
50.5 g/L (100 °C)[2]
Solubility slightly soluble in HF, ammonia
negligible in alcohol, acetone, SO2, dimethylformamide
Vapor pressure 1 mmHg @ 1077 °C[3]
Acidity (pKa) 3,20 (weak base, see HF)
Magnetic susceptibility (χ)
−16.4·10−6 cm3/mol
Refractive index (nD)
1.3252
Structure
Crystal structure
Cubic
Lattice constant
a = 462 pm
Molecular shape
Octahedral
Thermochemistry
Heat capacity (C)
46.82 J/(mol K)
Std molar
entropy (S298)
51.3 J/(mol K)
Std enthalpy of
formation fH298)
-573.6 kJ/mol
Gibbs free energy fG)
-543.3 kJ/mol
Pharmacology
ATC code
A01AA01 (WHO) A12CD01 (WHO),
V09IX06 (WHO) (18F)
Hazards
GHS labelling:
Pictograms
Acute Toxicity GHS07: Exclamation mark GHS08: Health hazard
Signal word
Danger
Hazard statements
H301, H315, H319, H335[4]
NFPA 704 (fire diamond)
NFPA 704 four-colored diamondHealth 3: Short exposure could cause serious temporary or residual injury. E.g. chlorine gasFlammability 0: Will not burn. E.g. waterInstability 0: Normally stable, even under fire exposure conditions, and is not reactive with water. E.g. liquid nitrogenSpecial hazards (white): no code
3
0
0
Flash point Non-flammable
Lethal dose or concentration (LD, LC):
LD50 (median dose)
52–130 mg/kg (oral in rats, mice, rabbits)[6]
NIOSH (US health exposure limits):
PEL (Permissible)
TWA 2.5 mg/m3[5]
REL (Recommended)
TWA 2.5 mg/m3[5]
IDLH (Immediate danger)
250 mg/m3 (as F)[5]
Safety data sheet (SDS) [4]
Related compounds
Other anions
Sodium chloride
Sodium bromide
Sodium iodide
Sodium astatide
Other cations
Lithium fluoride
Potassium fluoride
Rubidium fluoride
Caesium fluoride
Francium fluoride
Related compounds
TASF reagent
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)
Infobox references

Sodium fluoride (NaF) is an inorganic compound with the formula NaF. It is a colorless or white solid that is readily soluble in water. It is used in trace amounts in the fluoridation of drinking water to prevent tooth decay, and in toothpastes and topical pharmaceuticals for the same purpose. In 2021, it was the 291st most commonly prescribed medication in the United States, with more than 600,000 prescriptions.[7][8] It is also used in metallurgy and in medical imaging.

  1. ^ Wells, John C. (2008), Longman Pronunciation Dictionary (3rd ed.), Longman, pp. 313 and 755, ISBN 978-1-4058-8118-0. According to this source, an alternative pronunciation of the second word is /ˈflɔːrd/ and, in the UK, also /ˈflərd/.
  2. ^ Haynes, William M., ed. (2011). CRC Handbook of Chemistry and Physics (92nd ed.). CRC Press. p. 5.194. ISBN 978-1-4398-5511-9.
  3. ^ Lewis, R.J. Sax's Dangerous Properties of Industrial Materials. 10th ed. Volumes 1–3 New York, NY: John Wiley & Sons Inc., 1999., p. 3248
  4. ^ a b Sigma-Aldrich Co., Sodium Fluoride.
  5. ^ a b c NIOSH Pocket Guide to Chemical Hazards. "#0563". National Institute for Occupational Safety and Health (NIOSH).
  6. ^ Martel, B.; Cassidy, K. (2004), Chemical Risk Analysis: A Practical Handbook, Butterworth–Heinemann, p. 363, ISBN 978-1-903996-65-2
  7. ^ "The Top 300 of 2021". ClinCalc. Archived from the original on 15 January 2024. Retrieved 14 January 2024.
  8. ^ "Sodium Fluoride – Drug Usage Statistics". ClinCalc. Retrieved 14 January 2024.

and 28 Related for: Sodium fluoride information

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Sodium fluoride

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Sodium fluoride (NaF) is an inorganic compound with the formula NaF. It is a colorless or white solid that is readily soluble in water. It is used in...

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Fluoride

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for other halides. Sodium fluoride and sodium chloride adopt the same structure. For compounds containing more than one fluoride per cation, the structures...

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Toothpaste

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UK or Greece, the fluoride content is often higher; a sodium fluoride content of 0.312% w/w (1,450 ppm fluoride) or stannous fluoride content of 0.454%...

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Fluoride therapy

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cases, acute toxicity. Fluoride therapy typically uses the sodium fluoride form, though stannous fluoride may also be used. Fluoride decreases breakdown...

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Fluoride varnish

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concentration, form of fluoride, and dispensing method may vary depending on the manufacturer. While most fluoride varnishes contain 5% sodium fluoride at least one...

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Sodium monofluorophosphate

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"Fluoristat"; today Crest toothpastes use sodium fluoride or stannous fluoride. Compared to straight fluorides, sodium monofluorophosphate has slightly less...

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Lithium fluoride

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salt, FLiNaK, consists of a mixture of LiF, together with sodium fluoride and potassium fluoride. The primary coolant for the Molten-Salt Reactor Experiment...

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Fluoride toxicity

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consumption of large amounts of soluble fluoride salts is dangerous. Referring to a common salt of fluoride, sodium fluoride (NaF), the lethal dose for most adult...

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Fluorine deficiency

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stain teeth and prevent tooth decay. Fluoride salts, particularly sodium fluoride (NaF), are used in the treatment and prevention of osteoporosis. Symptoms...

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Sodium fluorosilicate

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material, ore refining, or other fluoride chemical (like sodium fluoride, magnesium silicofluoride, cryolite, aluminum fluoride) production. Fluorosilicic acid...

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Caesium fluoride

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Cs2CO3 + 2 HF → 2 CsF + H2O + CO2 CsF is more soluble than sodium fluoride or potassium fluoride in organic solvents. It is available in its anhydrous form...

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Distilled water

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completely remove all dissolved minerals such as calcium, magnesium, sodium, fluoride, potassium, iron, and zinc leaving a TDS of <1PPM, and reduce its electrical...

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Venipuncture

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can be centrifuged immediately after collection. A combination of sodium fluoride and potassium oxalate is used for glucose tests, as these additives...

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Silver diammine fluoride

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Silver diammine fluoride (SDF), also known as silver diamine fluoride in most of the dental literature, (although this is a chemical misnomer) is a topical...

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Fluorine

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affected parts may be required. Soluble fluorides are moderately toxic: 5–10 g sodium fluoride, or 32–64 mg fluoride ions per kilogram of body mass, represents...

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Sodium bifluoride

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to form sodium sulfate and hydrogen fluoride. Strong bases deprotonate bifluoride. For example, calcium hydroxide gives calcium fluoride. Sodium bifluoride...

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Potassium fluoride

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Potassium fluoride is the chemical compound with the formula KF. After hydrogen fluoride, KF is the primary source of the fluoride ion for applications...

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Topical fluoride

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ingredients. Common active ingredients include sodium fluoride, stannous fluoride, silver diamine fluoride. These ingredients account for different pharmacokinetic...

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Hydrogen fluoride

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Hydrogen fluoride (fluorane) is an inorganic compound with chemical formula HF. It is a very poisonous, colorless gas or liquid that dissolves in water...

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List of inorganic compounds

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Na2S2O4 Sodium ferrocyanide – Na4[Fe(CN)6] Sodium fluoride – NaF Sodium fluorosilicate – Na2[SiF6] Sodium formate – HCOONa Sodium hydride – NaH Sodium hydrogen...

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Water fluoridation controversy

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has found water fluoridation to be unlawful. Fluoride therapy Fluoride toxicity Hexafluorosilicic acid Sodium monofluorophosphate Pizzo G, Piscopo MR, Pizzo...

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Sodium chloride

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Sodium chloride /ˌsoʊdiəm ˈklɔːraɪd/, commonly known as edible salt, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium...

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Sodium salts

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inorganic sodium salts are sodium fluoride, sodium chloride, sodium bromide, sodium iodide, sodium sulfate, sodium bicarbonate and sodium carbonate. Sodium amide...

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Ionic crystal

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including potassium fluoride (KF), potassium chloride (KCl), potassium bromide (KBr), potassium iodide (KI), sodium fluoride (NaF). Sodium chloride (NaCl)...

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Mouthwash

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commercial mouthwashes. Anti-cavity mouthwashes use sodium fluoride to protect against tooth decay. Fluoride-containing mouthwashes are used as prevention for...

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Fluorine compounds

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increases. Dissolved fluorides produce basic solutions. The alkali metals form monofluorides. All are soluble and have the sodium chloride (rock salt)...

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Positron emission tomography

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Fluorodeoxyglucose ([18F]FDG or FDG) is commonly used to detect cancer; [18F]Sodium fluoride (Na18F) is widely used for detecting bone formation; Oxygen-15 (15O)...

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ATC code A12

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combination) A12CD01 Sodium fluoride A12CD02 Sodium monofluorophosphate A12CD51 Fluoride, combinations A12CE01 Sodium selenate A12CE02 Sodium selenite QA12CE99...

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