Global InformationOrthohepevirus A information
| Orthohepevirus A | |
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| TEM micrograph of Orthohepevirus A virions | |
Virus classification 
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| (unranked): | Virus |
| Realm: | Riboviria |
| Kingdom: | Orthornavirae |
| Phylum: | Kitrinoviricota |
| Class: | Alsuviricetes |
| Order: | Hepelivirales |
| Family: | Hepeviridae |
| Genus: | Orthohepevirus |
| Species: | Orthohepevirus A
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| Synonyms[1] | |
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The hepatitis E virus (HEV) is the causative agent of hepatitis E. It is of the species Orthohepevirus A.[a][2][1]
Globally, approximately 939 million corresponding to 1 in 8 individuals have ever experienced HEV infection. About 15–110 million individuals have recent or ongoing HEV infection.[3] The virus particle was first seen in 1983,[4] but was only molecularly cloned in 1989.[5]
- ^ a b c Purdy, Michael A.; et al. (June 2014). "New Classification Scheme for Hepeviridae" (PDF). International Committee on Taxonomy of Viruses (ICTV). Retrieved 1 May 2019.
The species Hepatitis E virus will be renamed Orthohepevirus A, and the species Avian hepatitis E virus will be renamed Orthohepevirus B.
- ^ "Hepeviridae - Hepeviridae - Positive-sense RNA Viruses - ICTV". www.ictv.global.
- ^ Li P, Liu J, Li Y, Su J, Ma Z, Bramer WM, Cao W, de Man RA, Peppelenbosch MP, Pan Q (July 2020). "The global epidemiology of hepatitis E virus infection: A systematic review and meta-analysis". Liver International. 40 (7): 1516–1528. doi:10.1111/liv.14468. PMC 7384095. PMID 32281721.
- ^ Balayan MS, Andjaparidze AG, Savinskaya SS, et al. (1983). "Evidence for a virus in non-A, non-B hepatitis transmitted via the fecal-oral route". Intervirology. 20 (1): 23–31. doi:10.1159/000149370. PMID 6409836.
- ^ Reyes GR, Purdy MA, Kim JP, et al. (1990). "Isolation of a cDNA from the virus responsible for enterically transmitted non-A, non-B hepatitis". Science. 247 (4948): 1335–9. Bibcode:1990Sci...247.1335R. doi:10.1126/science.2107574. PMID 2107574.
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