The Hepatitis B virus PRE stem-loop alpha (HBV PRE SL alpha) is an RNA structure that is shown to play a role in nuclear export of HBV mRNAs.
HBV PREalpha consists of a 30 nt stem-loop, with a 5 nt apical loop. The conserved stem-loop was predicted within the HBV PRE sequence and confirmed by mutagenesis.[1][2][3]
The exact role of this structure in nuclear export has not yet been determined.[4]
^Smith Gj, 3rd; Donello, JE; Lück, R; Steger, G; Hope, TJ (1998). "The hepatitis B virus post-transcriptional regulatory element contains two conserved RNA stem-loops which are required for function". Nucleic Acids Research. 26 (21): 4818–4827. doi:10.1093/nar/26.21.4818. PMC 147918. PMID 9776740.{{cite journal}}: CS1 maint: numeric names: authors list (link)
^Schwalbe, M; Ohlenschläger, O; Marchanka, A; Ramachandran, R; Häfner, S; Heise, T; Görlach, M (March 2008). "Solution structure of stem-loop alpha of the hepatitis B virus post-transcriptional regulatory element". Nucleic Acids Research. 36 (5): 1681–1689. doi:10.1093/nar/gkn006. PMC 2275152. PMID 18263618.
^Lim, CS; Brown, CM (September 2016). "Hepatitis B virus nuclear export elements: RNA stem-loop α and β, key parts of the HBV post-transcriptional regulatory element". RNA Biology. 13 (9): 743–747. doi:10.1080/15476286.2016.1166330. PMC 5013995. PMID 27031749.
^Chen, A; Panjaworayan T-Thienprasert, N; Brown, CM (7 July 2014). "Prospects for inhibiting the post-transcriptional regulation of gene expression in hepatitis B virus". World Journal of Gastroenterology. 20 (25): 7993–8004. doi:10.3748/wjg.v20.i25.7993. PMC 4081668. PMID 25009369.
and 22 Related for: Hepatitis B virus PRE alpha information
The HepatitisBvirusPRE stem-loop alpha (HBV PRE SL alpha) is an RNA structure that is shown to play a role in nuclear export of HBV mRNAs. HBV PREalpha...
HepatitisBvirus (HBV) is a partially double-stranded DNA virus, a species of the genus Orthohepadnavirus and a member of the Hepadnaviridae family of...
Hepatitis D is a type of viral hepatitis caused by the hepatitis delta virus (HDV). HDV is one of five known hepatitisviruses: A, B, C, D, and E. HDV...
HepatitisB is an infectious disease caused by the HepatitisBvirus (HBV) that affects the liver; it is a type of viral hepatitis. It can cause both acute...
liver failure, and liver cancer. Hepatitis is most commonly caused by the virus hepatovirus A, B, C, D, and E. Other viruses can also cause liver inflammation...
Hepatitis C is an infectious disease caused by the hepatitis C virus (HCV) that primarily affects the liver; it is a type of viral hepatitis. During the...
(target) through which the hepatitis delta and hepatitisBviruses enter liver cells. By blocking the entry of the virus into the cells, it limits the...
Hutin YJ, Bell BP (October 2006). "The contributions of hepatitisBvirus and hepatitis C virus infections to cirrhosis and primary liver cancer worldwide"...
in panel B. Erythroviruses belong to the Parvoviridae family of small DNA viruses. Human parvovirus B19 is a non-enveloped, icosahedral virus that contains...
designed to help deal with HIV, herpes viruses, the hepatitisB and C viruses, and influenza A and Bviruses. Viruses use the host's cells to replicate and...
deficiency, or hepatitis C virus infection (e.g. clinical hepatitis, circulating hepatitis C virus). The association of hepatitis C virus infection with...
"Deciphering the Origin and Evolution of HepatitisBViruses by Means of a Family of Non-enveloped Fish Viruses". Cell Host & Microbe. 22 (3): 387–399.e6...
detectable virus in hepatitisB and C infected cells. In hepatitisB, siRNA silencing was used to target the surface antigen on the hepatitisBvirus and led...
respirovirus, formerly Sendai virus (SeV) and previously also known as murine parainfluenza virus type 1 or hemagglutinating virus of Japan (HVJ), is an enveloped...
Chikungunya is an infection caused by the Chikungunya virus (CHIKV). The disease was first identified in 1952 in Tanzania and named based on the Kimakonde...
medium-sized (90–100 nm), nonenveloped (without an outer lipid bilayer) viruses with an icosahedral nucleocapsid containing a double-stranded DNA genome...
leukoencephalopathy (PML) caused by JC virus reactivation HepatitisB reactivation Other viral infections Immune toxicity, with depletion of B cells in 70% to 80% of...
tested had detectable blood in a quantity sufficient to pass on a virus such as hepatitisB. From 1984 to 1985, a weight-loss clinic in Los Angeles administered...
and other developing countries is increasing due to an increase in hepatitis C virus infections. It is more than three times as common in males as in females...
infections, cytotoxic T cells are mostly effective against viruses. During hepatitisBvirus (HBV) infection, cytotoxic T cells kill infected cells and...
Global Information