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Hematoxylin body information


In diagnostic pathology, a hematoxylin body, or LE body, is a dense, homogeneous, basophilic particle, easily stainable with hematoxylin. It consists of degraded nuclear material from an injured cell, along with autoantibodies and a limited amount of cytoplasm.[1][2][3]

Hematoxylin bodies occur in systemic lupus erythematosus. The hematoxylin body may be green, blue, or purple with the Papanicolaou stain and magenta with Romanowsky stains.[4] The material has a positive Feulgen stain reaction, which is typical of DNA.[5] The material may be extracellular or may be ingested by leukocytes, which are then known as LE cells.[2][6][7]

  1. ^ Cite error: The named reference Chan2014 was invoked but never defined (see the help page).
  2. ^ a b Cite error: The named reference MD was invoked but never defined (see the help page).
  3. ^ Cite error: The named reference Moreland2004 was invoked but never defined (see the help page).
  4. ^ Cite error: The named reference Cibas2013 was invoked but never defined (see the help page).
  5. ^ Cite error: The named reference Hollander1966 was invoked but never defined (see the help page).
  6. ^ Cite error: The named reference Wallace2007 was invoked but never defined (see the help page).
  7. ^ Cite error: The named reference Kumar2014 was invoked but never defined (see the help page).

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Hematoxylin body

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diagnostic pathology, a hematoxylin body, or LE body, is a dense, homogeneous, basophilic particle, easily stainable with hematoxylin. It consists of degraded...

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LE cell

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of another cell. The denatured material is an absorbed hematoxylin body (also called an LE body). They are a characteristic of lupus erythematosus, but...

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Azzopardi phenomenon

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basophilic material on hematoxylin-eosin stain. The Azzopardi phenomenon is distinguished from the similar basophilic hematoxylin body. [citation needed]...

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Eosinophilic

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example, Lewy and Mallory bodies. Some cells are also described as eosinophilic, such as Leukocytes. Basophilic (affinity to hematoxylin) Eosinophil Eosinophilia...

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Micrometastasis

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the tissue under the microscope. The typical biopsy procedure involves hematoxylin and eosin (H&E) staining of specific markers that correspond to the particular...

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Chromatolysis

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cellular neuroscience, chromatolysis is the dissolution of the Nissl bodies in the cell body of a neuron. It is an induced response of the cell usually triggered...

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Red neuron

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degradation of the nucleus and loss of Nissl bodies which are normally stained blue (basophilic) on hematoxylin & eosin staining (H&E stain). This leaves...

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Wuchereria bancrofti

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transparent. The body is quite delicate, making removing it from tissues difficult. It has a short cephalic or head region connected to the main body by a short...

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Soft tissue

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Soft tissue is all the tissue in the body that is not hardened by the processes of ossification or calcification such as bones and teeth. Soft tissue connects...

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Histology

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used. Hematoxylin and eosin (H&E stain) is one of the most commonly used stains in histology to show the general structure of the tissue. Hematoxylin stains...

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Granuloma

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granuloma is most often an infectious pathogen or a substance foreign to the body, but sometimes the offending antigen is unknown (as in sarcoidosis).[citation...

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Lactotropic cell

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numerous other effects in both sexes. Prolactin cells are acidophilic by hematoxylin & eosin stains and, If these cells undergo neoplastic transformation...

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Kidney

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the specimen using light microscopy with multiple staining techniques (hematoxylin and eosin/H&E, PAS, trichrome, silver stain) on multiple level sections...

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Hepatocyte

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difficult to visualise by light microscopy. The hepatocyte is a cell in the body that manufactures serum albumin, fibrinogen, and the prothrombin group of...

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Goblet cell

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acids within the nucleus and rough endoplasmic reticulum staining with hematoxylin. Mucin within the granules stains pale in routine histology sections...

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Histopathology

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commonly used stain in histology is a combination of hematoxylin and eosin (often abbreviated H&E). Hematoxylin is used to stain nuclei blue, while eosin stains...

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List of parasites of humans

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Lymphatic filariasis Wuchereria bancrofti lymphatic system thick blood smears stained with hematoxylin. tropical and subtropical mosquito, bites at night...

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Atherosclerosis

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disease, or kidney disorders, depending on which body part(s) the affected arteries are located in the body. The exact cause of atherosclerosis is unknown...

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Cysticercus

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is also known as bladder worm. It is filled with fluid, in which the main body of the larva, called scolex (which will eventually form the head of the tapeworm)...

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Neutrophil

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eosinophils. The name neutrophil derives from staining characteristics on hematoxylin and eosin (H&E) histological or cytological preparations. Whereas basophilic...

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Mohs surgery

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tissue between 5 and 10 micrometres using a cryostat, and staining with hematoxylin and eosin (H&E) or other stains (Including Toluidine Blue) Interpretation...

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Spironolactone

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cytoplasmic inclusions surrounded by clear halos in preparations stained with hematoxylin and eosin. In the United States, spironolactone is considered pregnancy...

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Pneumocystis jirovecii

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alveoli, producing an exudate seen as honeycomb/cotton candy appearance on hematoxylin and eosin-stained slides. Drug of choice is trimethoprim/sulfamethoxazole...

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Fibroadenoma

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pattern. Histopathologic image of breast fibroadenoma. Core needle biopsy. Hematoxylin & eosin stain. Histopathologic image of breast fibroadenoma showing proliferation...

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Staining

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be useful. Some complementing stains used alongside Bismark brown are Hematoxylin and Toluidine blue which provide better contrast within the histology...

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