The ear of a 63-year-old man, photographed sixteen days after Mohs surgery to remove a squamous cell carcinoma on the left upper edge of the ear, and three days after removal of the sutures.
MeSH
D015580
[edit on Wikidata]
Mohs surgery, developed in 1938 by a general surgeon, Frederic E. Mohs, is microscopically controlled surgery used to treat both common and rare types of skin cancer. During the surgery, after each removal of tissue and while the patient waits, the tissue is examined for cancer cells. That examination dictates the decision for additional tissue removal. Mohs surgery is the gold standard method for obtaining complete margin control during removal of a skin cancer (complete circumferential peripheral and deep margin assessment - CCPDMA) using frozen section histology.[1] CCPDMA or Mohs surgery allows for the removal of a skin cancer with very narrow surgical margin and a high cure rate.
The cure rate with Mohs surgery cited by most studies is between 97% and 99.8% for primary basal-cell carcinoma, the most common type of skin cancer.[2]: 13 Mohs procedure is also used for squamous cell carcinoma, but with a lower cure rate. Recurrent basal-cell cancer has a lower cure rate with Mohs surgery, more in the range of 94%.[2]: 7 It has been used in the removal of melanoma-in-situ (cure rate 77% to 98% depending on surgeon), and certain types of melanoma (cure rate 52%).[2]: 4 [3]: 211–20
Other indications for Mohs surgery include dermatofibrosarcoma protuberans, keratoacanthoma, spindle cell tumors, sebaceous carcinomas, microcystic adnexal carcinoma, merkel cell carcinoma, Paget's disease of the breast, atypical fibroxanthoma, and leiomyosarcoma.[3]: 193–203 [4] Because the Mohs procedure is micrographically controlled, it provides precise removal of the cancerous tissue, while healthy tissue is spared. Mohs surgery can also be more cost effective than other surgical methods, when considering the cost of surgical removal and separate histopathological analysis. However, Mohs surgery should be reserved for the treatment of skin cancers in anatomic areas where tissue preservation is of utmost importance (face, neck, hands, lower legs, feet, genitals).[4]
^Minton TJ (August 2008). "Contemporary Mohs surgery applications". Current Opinion in Otolaryngology & Head and Neck Surgery. 16 (4): 376–80. doi:10.1097/MOO.0b013e3283079cac. PMID 18626258. S2CID 10668953.
^ abcMikhail, George R.; Mohs, Frederic Edward (1991). Mohs micrographic surgery. Philadelphia: W.B. Saunders. p. 13. ISBN 978-0-7216-3415-9.
^ abGross, Kenneth Gary; Steinman, Howard K.; Rapini, Ronald P. (1999). Mohs Surgery: Fundamentals and Techniques. Saint Louis: Mosby. ISBN 978-0-323-00012-3.
^ abAd Hoc Task Force.; et al. (October 2012). "AAD/ACMS/ASDSA/ASMS 2012 appropriate use criteria for Mohs micrographic surgery: a report of the American Academy of Dermatology, American College of Mohs Surgery, American Society for Dermatologic Surgery Association, and the American Society for Mohs Surgery". Journal of the American Academy of Dermatology. 67 (4): 531–50. doi:10.1016/j.jaad.2012.06.009. PMID 22959232.
Mohssurgery, developed in 1938 by a general surgeon, Frederic E. Mohs, is microscopically controlled surgery used to treat both common and rare types...
Society for MohsSurgery or through one-year Mohssurgery fellowship training programs administered by the American College of MohsSurgery. In 2020, the...
membership organization for Mohs surgeons. The American College of MohsSurgery was established in 1967 by Frederic E. Mohs, a general surgeon based at...
Mohs or MoHS can refer to: Friedrich Mohs, a 19th-century German geologist who developed: Mohs scale, a scale used in materials science to describe hardness...
of Mohssurgery.) Especially in more cosmetically-sensitive areas, and where the clinical diagnosis is reasonably certain, alternatives to surgery may...
margin controlled surgery (CCPDMA) can be performed using a variety of tissue cutting and mounting methods, including Mohssurgery. The frozen section...
Song Ji (2019-08-13). "The efficacy of Mohs micrographic surgery over the traditional wide local excision surgery in the cure of dermatofibrosarcoma protuberans"...
discussions of basal-cell carcinoma and squamous-cell carcinoma. Mohs' micrographic surgery (Mohssurgery) is a technique used to remove the cancer with the least...
laparoscopic surgery laser surgerymohssurgery radiofrequency ablation robotic surgery and other forms of surgery. thoracoscopic surgery One of the first...
pioneered several orthopedic surgeries Frederic E. Mohs, developed the Mohs Micrographic Surgery technique (MMS) aka Mohssurgery in 1938 to remove skin cancer...
radiation therapy; and surgical excision, including Mohssurgery (microscopically controlled surgery used to remove and test cancerous tissue). Escharotics...
cancers, especially skin cancers. There are two forms of CCPDMA surgery: Mohssurgery and surgical excision coupled with margin assessment. Other examples...
contracting Covid again in September 2023). In January 2023, Biden underwent Mohssurgery to remove two basal-cell carcinoma lesions from her face and chest. Biden...
CCPDMA. A special type of CCPDMA is named after a general surgeon, or the Mohssurgery method. Gross examination Frozen section Fixation & Embedding Histopathologic...
Craniofacial surgery Dermatology Endocrinology Family and General Medicine Gastroenterologic surgery Gastroenterology General Practice General surgery Geriatrics...
Mohssurgery has been done with cure rate reported to be 77%. The "double scalpel" peripheral margin controlled excision method approximates the Mohs...
patients may forgo traditional biopsy techniques and instead choose Mohssurgery. There are four main types of skin biopsies: shave biopsy, punch biopsy...
full-thickness burns, surgical wounds, split-thickness graft donor sites, Mohssurgery defects, refractory decubiti, and chronic ulcers. They can also be applied...
Liposuction, or simply lipo, is a type of fat-removal procedure used in plastic surgery. Evidence does not support an effect on weight beyond a couple of months...
tumor margins, as in Mohssurgery, or determination of tumor malignancy, when a tumor is discovered incidentally during surgery. Ultramicrotomy is a method...
procedure. O'Connell, Norman (2013). Bailey & Love's short practice of surgery (26th ed.). Boca Raton: CRC Press. ISBN 978-1444121278. Often used in conjunction...
disadvantage. In a patient whose basal-cell carcinoma was excised with Mohssurgery, the scar of the nasal reconstruction (an 11 mm full-thickness, laterally...
Below is a list of common and eponymous plastic surgery flaps with their classification and common usage. (NB - the terms interpolation flap and pedicle...
basal cell cancer. Essentially, all the prognostic factors that apply to Mohssurgery and standard surgical excision will also apply to EDC.[citation needed]...
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